Kai Zhang^*, Huajun Chen^†, Ye Wang^‡, Lin Yang^§, Chengzhi Zhou^¶, Weiqiang Yin^#, Guangsuo Wang^§, Xinru Mao^**, Jianxing Xiang^**, Bing Li^**, Tengfei Zhang^**, Shihong Fei^*

Oncology Research, Vol.27, No.5, pp. 575-582, 2019, DOI:10.3727/096504018X15344979253618

Abstract RET rearrangement has been proven as an oncogenic driver in patients with lung cancer. However, the prevalence, clinical characteristics, molecular features, and therapeutic options in RET-rearranged patients remain unclear, especially in Chinese lung cancer patients. We retrospectively collected 6,125 Chinese lung cancer patients who have been profiled using next-generation sequencing (NGS). The clinical demographics and molecular features of RET rearrangement-positive patients were analyzed. RET rearrangements were identified in 84 patients with a proportion of 1.4% in our cohort. The median age at diagnosis was 58 years, and it mainly occurred in females with adenocarcinoma histology. KIF5B-RET was the… More >

Chung Wen Hung, Wei Lung Mao, Han Yi Huang

Intelligent Automation & Soft Computing, Vol.25, No.2, pp. 329-341, 2019, DOI:10.31209/2019.100000093

Abstract Nonlinear system modeling and identification is the one of the most important areas in engineering problem. The paper presents the recurrent fuzzy neural network (RFNN) trained by modified particle swarm optimization (MPSO) methods for identifying the dynamic systems and chaotic observation prediction. The proposed MPSO algorithms mainly modify the calculation formulas of inertia weights. Two MPSOs, namely linear decreasing particle swarm optimization (LDPSO) and adaptive particle swarm optimization (APSO) are developed to enhance the convergence behavior in learning process. The RFNN uses MPSO based method to tune the parameters of the membership functions, and it More >

Yu-Cheng Chou¹, Wei-Chieh Liao², Yan-Liang Chen², Ming Chang², Po Ting Lin³

Intelligent Automation & Soft Computing, Vol.25, No.1, pp. 79-90, 2019, DOI:10.31209/2018.100000011

Abstract This paper presents the Distributed Heterogeneous Inspection System (DHIS), which comprises two CUDA workstations and is equipped with CPU distributed computing, CPU concurrent computing, and GPU concurrent computing functions. Thirty-two grayscale images, each with 5,000× 12,288 pixels and simulated defect patterns, were created to evaluate the performances of three system configurations: (1) DHIS; (2) two CUDA workstations with CPU distributed computing and GPU concurrent computing; (3) one CUDA workstation with GPU concurrent computing. Experimental results indicated that: (1) only DHIS can satisfy the time limit, and the average turnaround time of DHIS is 37.65% of More >

Varun Aggarwal¹, Christopher J. Petit², Andrew C. Glatz^3，4, Bryan H. Goldstein⁵, Athar M. Qureshi¹

Congenital Heart Disease, Vol.14, No.1, pp. 110-115, 2019, DOI:10.1111/chd.12709

Abstract The use of prostaglandin‐E1 immediately after birth and subsequent surgical crea‐ tion of the modified Blalock‐Taussig shunt (BTS) shunt have remarkably improved the prognosis and survival of children with congenital heart disease and ductal‐depend‐ ent pulmonary blood flow (PBF). Despite the advancement in surgical techniques, bypass strategies, and postoperative management, significant morbidity and mortal‐ ity after BTS still remain. Patent ductus arteriosus stenting has been shown to be as an acceptable alternative to BTS placement in select infants with ductal‐dependent PBF. Newer procedural techniques and equipment, along with operator experience have all contributed to procedural More >

Tarek A ATIA

BIOCELL, Vol.43, No.4, pp. 253-262, 2019, DOI:10.32604/biocell.2019.08180

Abstract Recurring miscarriage (RM) is a frustrating reproductive complication with variable etiology. Numerous genetic defects have been known to play a crucial role in the etiology of RM. Chromosomal abnormalities are frequently detected, while other genetic defects cannot be diagnosed through routine research, such as cryptic chromosomal anomalies, single nucleotide polymorphism, single-gene defect, and gene copy number variation. Diagnostic laboratories have recently used variable advanced techniques to detect potential genetic abnormalities in couples with RM and/or in products of conception. Here we aim to summarize the known genetic causes of RM, with a focus on the More >

Yu Sun^1,2,*, Qiyuan Gao³, Xiaofan Du³, Zhao Gu³

CMC-Computers, Materials & Continua, Vol.61, No.3, pp. 1365-1375, 2019, DOI:10.32604/cmc.2019.06294

Abstract In this advanced age, when smart phones are the norm, people utilize social networking, online shopping, and even private information storage through smart phones. As a result, identity authentication has become the most critical security activity in this period of the intelligent craze. By analyzing the shortcomings of the existing authentication methods, this paper proposes an identity authentication method based on the behavior of smartphone users. Firstly, the sensor data and touch-screen data of the smart phone users are collected through android programming. Secondly, the eigenvalues of this data are extracted and sent to the More >

Viviane Timmermann¹, Kevin Vincent², Joakim Sundnes¹, Andrew D. McCulloch^2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 133-133, 2019, DOI:10.32604/mcb.2019.07311

Abstract Heterogeneous mechanical dyskinesis has been implicated in arrhythmogenic phenotypes. Strain-induced perturbations to cardiomyocyte electrophysiology (EP) may trigger arrhythmias via a variety of mechano-electric feedback (MEF) mechanisms. While the role of stretch-activated ionic currents (SACs) has been investigated intensively using computational models, experimental studies have shown that mechanical strain can also trigger intra- and inter-cellular calcium waves. To investigate whether the inherent strain dependence of myofilament calcium affinity may promote arrhythmogenic intra- and inter-cellular calcium waves under conditions of pathologic mechanical heterogeneity, we coupled a mathematical model of excitation-contraction coupling (ECC) in rabbit ventricular myocytes to… More >

Jun Wu^1,*, Kui Hu¹, Yiwei Cheng², Ji Wang¹, Chao Deng^2,*, Yuanhan Wang³

Structural Durability & Health Monitoring, Vol.13, No.3, pp. 317-329, 2019, DOI:10.32604/sdhm.2019.05571

Abstract Residual useful life (RUL) prediction is a key issue for improving efficiency of aircraft engines and reducing their maintenance cost. Owing to various failure mechanism and operating environment, the application of classical models in RUL prediction of aircraft engines is fairly difficult. In this study, a novel RUL prognostics method based on using ensemble recurrent neural network to process massive sensor data is proposed. First of all, sensor data obtained from the aircraft engines are preprocessed to eliminate singular values, reduce random fluctuation and preserve degradation trend of the raw sensor data. Secondly, three kinds More >

Yimeng Zhai¹, Aidong Deng^1,*, Jing Li^1,2, Qiang Cheng¹, Wei Ren³

Journal on Artificial Intelligence, Vol.1, No.1, pp. 19-27, 2019, DOI:10.32604/jai.2019.05817

Abstract In order to acquire the degradation state of rolling bearings and achieve predictive maintenance, this paper proposed a novel Remaining Useful Life (RUL) prediction of rolling bearings based on Long Short Term Memory (LSTM) neural net-work. The method is divided into two parts: feature extraction and RUL prediction. Firstly, a large number of features are extracted from the original vibration signal. After correlation analysis, the features that can better reflect the degradation trend of rolling bearings are selected as input of prediction model. In the part of RUL prediction, LSTM that making full use of More >

Xiaorong Zhao¹, Hongjin Zhu¹, Peizhong Shi¹, Chunpeng Ge², Xiufang Qian^1,*, Honghui Fan¹, Zhongjun Fu¹

CMC-Computers, Materials & Continua, Vol.60, No.1, pp. 133-145, 2019, DOI:10.32604/cmc.2019.05661

Abstract With the rapid development of ultra-wideband communications, the design requirements of CMOS radio frequency integrated circuits have become increasingly high. Ultra-wideband (UWB) low noise amplifiers are a key component of the receiver front end. The paper designs a high power gain (S₂₁) and low noise figure (NF) common gate (CG) CMOS UWB low noise amplifier (LNA) with an operating frequency range between 3.1 GHz and 10.6 GHz. The circuit is designed by TSMC 0.13 μm RF CMOS technology. In order to achieve high gain and flat gain as well as low noise figure, the circuit uses… More >