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  • Open Access

    EDITORIAL

    Introduction to the Special Issue on Modeling and Simulation of Fluid Flows in Fractured Porous Media: Current Trends and Prospects

    Qian Yin1,2,3, Yujing Jiang2,3,*, Richeng Liu1,3

    CMES-Computer Modeling in Engineering & Sciences, Vol.126, No.2, pp. 437-441, 2021, DOI:10.32604/cmes.2021.015432 - 21 January 2021

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Image Steganography in Spatial Domain: Current Status, Techniques, and Trends

    Adeeb M. Alhomoud*

    Intelligent Automation & Soft Computing, Vol.27, No.1, pp. 69-88, 2021, DOI:10.32604/iasc.2021.014773 - 07 January 2021

    Abstract This research article provides an up-to-date review of spatial-domain steganography. Maintaining the communication as secure as possible when transmitting secret data through any available communication channels is the target of steganography. Currently, image steganography is the most developed field, with several techniques are provided for different image formats. Therefore, the general image steganography including the fundamental concepts, the terminology, and the applications are highlighted in this paper. Further, the paper depicts the essential characteristics between information hiding and cryptography systems. In addition, recent well-known techniques in the spatial-domain steganography, such as LSB and pixel value More >

  • Open Access

    ARTICLE

    A Hybrid Deep Learning Model for COVID-19 Prediction and Current Status of Clinical Trials Worldwide

    Shwet Ketu*, Pramod Kumar Mishra

    CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 1896-1919, 2021, DOI:10.32604/cmc.2020.012423 - 26 November 2020

    Abstract Infections or virus-based diseases are a significant threat to human societies and could affect the whole world within a very short time-span. Corona Virus Disease-2019 (COVID-19), also known as novel coronavirus or SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus-2), is a respiratory based touch contiguous disease. The catastrophic situation resulting from the COVID-19 pandemic posed a serious threat to societies globally. The whole world is making tremendous efforts to combat this life-threatening disease. For taking remedial action and planning preventive measures on time, there is an urgent need for efficient prediction models to confront the COVID-19 outbreak.… More >

  • Open Access

    RESIDENT’S CORNER

    Wunderlich syndrome secondary to cyst rupture and concurrent anticoagulation

    Clarissa M. Gurbani1, Vincent Khor2, Jeffrey J. Leow1, Melissa H.W. Tay3, Yew-Lam Chong1

    Canadian Journal of Urology, Vol.27, No.3, pp. 10270-10272, 2020

    Abstract Wunderlich syndrome (WS) is a rare triad of flank pain, flank mass and hypovolemic shock and is classically attributed to angiomyolipomata or neoplasms. Treatment is guided by clinical severity: conservative, selective arterial embolization, or nephrectomy. We report an atypical case of a 69-year old man with a pre-existing 9 cm left renal tumor who developed WS secondary to anticoagulation and simple cyst rupture from his contralateral kidney, complicated by abdominal compartment syndrome with hemodynamic instability despite inotropic support and robust resuscitation. Early recognition and source control via radical nephrectomy were essential in securing a positive More >

  • Open Access

    ARTICLE

    The current state of continence in Canada: a population representative epidemiological survey

    Christina Shaw1, Jacky Cahill2, Adrian Wagg1,2

    Canadian Journal of Urology, Vol.27, No.4, pp. 10300-10305, 2020

    Abstract Introduction: Data on the prevalence of lower urinary tract symptoms (LUTS) and urinary incontinence (UI) in Canada are dated. This study aims to describe the current prevalence of LUTS and UI, to assess the state of knowledge of these conditions, the treatment for them and the treatment experience of symptomatic persons.
    Materials and methods: A nationally representative adult (≥ 18 years) sample was surveyed using a questionnaire based on the EPIC study. The margin of error associated with this probability-based sample was +/-3.1%, 19 times out of 20.
    Results: Of the 1000 people contacted (52% female, 48% male),… More >

  • Open Access

    ARTICLE

    Endostar, an Antiangiogenesis Inhibitor, Combined With Chemoradiotherapy for Locally Advanced Cervical Cancer

    Heming Lu*†1, Yuying Wu‡1, Xu Liu, Huixian Huang, Hailan Jiang, Chaohua Zhu, Yuping Man§, Zhaohong Chen, Xianfeng Long, Qiang Pang, Luxing Peng, Xianglong Li, Junzhao Gu, Shan Deng, Ligang Xing*

    Oncology Research, Vol.28, No.9, pp. 929-944, 2020, DOI:10.3727/096504021X16318716607908

    Abstract This phase II randomized clinical trial aimed to assess the efficacy and toxicity of Endostar, an antiangiogenesis inhibitor, combined with concurrent chemoradiotherapy (CCRT) for locally advanced cervical cancer (LACC). Patients with LACC were randomly assigned to either CCRT plus Endostar (CCRT+E arm) or CCRT alone (CCRT arm). All patients received pelvic intensity-modulated radiation therapy (IMRT) and brachytherapy. Weekly cisplatin was administered concurrently with IMRT. Patients in the CCRT+E arm also received concurrent Endostar every 3 weeks for two cycles. The primary endpoint was progression-free survival (PFS) and acute toxicities. The exploratory endpoint was the impact… More >

  • Open Access

    ARTICLE

    Two polymorphisms in methylenetetrahydrofolate reductase gene (C677T and A1298C) frequently associated with recurrent spontaneous abortion show no association in Saudi women

    AFRAH ALKHURIJI1, ATEKAH ABDULLAH MOHAMMED ALRAQIBAH1, AMAAL AWAD ALHARBI1, ZENEB BABAY2, FATIMAH BASIL AL-MUKAYNIZI3, ARWA ALTHOMALI3, SONYA S. ABDEL-RAZEQ4, ARJUMAND S. WARSY5

    BIOCELL, Vol.44, No.4, pp. 613-621, 2020, DOI:10.32604/biocell.2020.09652 - 24 December 2020

    Abstract Methylenetetrahydrofolate reductase (MTHFR) deficiency is the most common genetic cause of hyperhomocysteinemia, which has been implicated in the etiology of recurrent spontaneous abortion (RSA). This study was designed to investigate the association between two single nucleotide polymorphisms (SNP) (rs1801133 [C677T] and rs1801131 [A1298C]) in the MTHFR gene and RSA, in Saudis. These two SNPs were selected as these polymorphisms have a different effect on the activity and stability of the enzyme, and significantly diverse effects have been reported in relation to the association with RSA. Ethical approval was acquired from the IRB at King Saud… More >

  • Open Access

    REVIEW

    The Effect of Carnitine Supplementation on Left Ventricular Function: Lessons from Current Evidence and Insights for Future Studies

    Rohit S. Loomba1,2, Enrique G. Villarreal3,*, Riddhi Patel1, Samantha Udarbe1, Vincent Dorsey1, Kristen Nelson-McMillan1,4, Saul Flores5,6

    Congenital Heart Disease, Vol.15, No.6, pp. 447-455, 2020, DOI:10.32604/CHD.2020.012927 - 02 November 2020

    Abstract Introduction: In children, data on the effects on carnitine supplementation and myocardial function are limited. A few studies have investigated the relationship between serum carnitine levels in the setting of depressed cardiac function and have demonstrated possible benefits. As such, this systematic review and meta-analyses aimed to assess the effects carnitine supplementation on left ventricular function. Materials and Methods: A systematic review of the literature was performed to identify full text manuscripts in English. PubMed, EMBASE, and the Cochrane databases were queried. Studies were included with data from pediatric patients, that used carnitine supplementation and included preand… More >

  • Open Access

    ARTICLE

    A Subsynchronous Oscillation Suppression Method Based on Self-Adaptive Auto Disturbance Rejection Proportional Integral Control of Voltage Source Converter Based Multi-Terminal Direct Current System with Doubly-Fed Induction Generator-Based Wind Farm Access

    Miaohong Su1, Haiying Dong1,2,*, Kaiqi Liu1, Weiwei Zou1

    Energy Engineering, Vol.117, No.6, pp. 439-452, 2020, DOI:10.32604/EE.2020.011805 - 16 October 2020

    Abstract A subsynchronous oscillation suppression strategy based on self-adaptive auto disturbance rejection proportional integral controller is proposed for doublyfed induction generator-based wind farm integrated into grid through voltage source converter based multi-terminal direct current. In this strategy, the nonlinear PI controller is constructed by fal function to replace the traditional linear PI controller, and then the tracking differentiator is used to arrange the appropriate transition process in combination with the idea of active disturbance rejection control, and the self-adaptive auto disturbance rejection proportional integral controller is designed. By applying the controller to the inner loop of the… More >

  • Open Access

    ARTICLE

    Combining Trend-Based Loss with Neural Network for Air Quality Forecasting in Internet of Things

    Weiwen Kong1, Baowei Wang1,2,3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.2, pp. 849-863, 2020, DOI:10.32604/cmes.2020.012818 - 12 October 2020

    Abstract Internet of Things (IoT) is a network that connects things in a special union. It embeds a physical entity through an intelligent perception system to obtain information about the component at any time. It connects various objects. IoT has the ability of information transmission, information perception,andinformationprocessing.Theairqualityforecastinghasalways been an urgent problem, which affects people’s quality of life seriously. So far, many air quality prediction algorithms have been proposed, which can be mainly classifed into two categories. One is regression-based prediction, the other is deep learning-based prediction. Regression-based prediction is aimed to make use of the classical… More >

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