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  • Open Access

    ABSTRACT

    Mechano-Electric Feedback and Arrhythmogenic Current Generation in A Computational Model of Coupled Myocytes

    Viviane Timmermann1, Kevin Vincent2, Joakim Sundnes1, Andrew D. McCulloch2,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 133-133, 2019, DOI:10.32604/mcb.2019.07311

    Abstract Heterogeneous mechanical dyskinesis has been implicated in arrhythmogenic phenotypes. Strain-induced perturbations to cardiomyocyte electrophysiology (EP) may trigger arrhythmias via a variety of mechano-electric feedback (MEF) mechanisms. While the role of stretch-activated ionic currents (SACs) has been investigated intensively using computational models, experimental studies have shown that mechanical strain can also trigger intra- and inter-cellular calcium waves. To investigate whether the inherent strain dependence of myofilament calcium affinity may promote arrhythmogenic intra- and inter-cellular calcium waves under conditions of pathologic mechanical heterogeneity, we coupled a mathematical model of excitation-contraction coupling (ECC) in rabbit ventricular myocytes to… More >

  • Open Access

    ARTICLE

    Ensemble Recurrent Neural Network-Based Residual Useful Life Prognostics of Aircraft Engines

    Jun Wu1,*, Kui Hu1, Yiwei Cheng2, Ji Wang1, Chao Deng2,*, Yuanhan Wang3

    Structural Durability & Health Monitoring, Vol.13, No.3, pp. 317-329, 2019, DOI:10.32604/sdhm.2019.05571

    Abstract Residual useful life (RUL) prediction is a key issue for improving efficiency of aircraft engines and reducing their maintenance cost. Owing to various failure mechanism and operating environment, the application of classical models in RUL prediction of aircraft engines is fairly difficult. In this study, a novel RUL prognostics method based on using ensemble recurrent neural network to process massive sensor data is proposed. First of all, sensor data obtained from the aircraft engines are preprocessed to eliminate singular values, reduce random fluctuation and preserve degradation trend of the raw sensor data. Secondly, three kinds More >

  • Open Access

    ARTICLE

    Remaining Useful Life Prediction of Rolling Bearings Based on Recurrent Neural Network

    Yimeng Zhai1, Aidong Deng1,*, Jing Li1,2, Qiang Cheng1, Wei Ren3

    Journal on Artificial Intelligence, Vol.1, No.1, pp. 19-27, 2019, DOI:10.32604/jai.2019.05817

    Abstract In order to acquire the degradation state of rolling bearings and achieve predictive maintenance, this paper proposed a novel Remaining Useful Life (RUL) prediction of rolling bearings based on Long Short Term Memory (LSTM) neural net-work. The method is divided into two parts: feature extraction and RUL prediction. Firstly, a large number of features are extracted from the original vibration signal. After correlation analysis, the features that can better reflect the degradation trend of rolling bearings are selected as input of prediction model. In the part of RUL prediction, LSTM that making full use of More >

  • Open Access

    ARTICLE

    A High Gain, Noise Cancelling 3.1-10.6 GHz CMOS LNA for UWB Application

    Xiaorong Zhao1, Hongjin Zhu1, Peizhong Shi1, Chunpeng Ge2, Xiufang Qian1,*, Honghui Fan1, Zhongjun Fu1

    CMC-Computers, Materials & Continua, Vol.60, No.1, pp. 133-145, 2019, DOI:10.32604/cmc.2019.05661

    Abstract With the rapid development of ultra-wideband communications, the design requirements of CMOS radio frequency integrated circuits have become increasingly high. Ultra-wideband (UWB) low noise amplifiers are a key component of the receiver front end. The paper designs a high power gain (S21) and low noise figure (NF) common gate (CG) CMOS UWB low noise amplifier (LNA) with an operating frequency range between 3.1 GHz and 10.6 GHz. The circuit is designed by TSMC 0.13 μm RF CMOS technology. In order to achieve high gain and flat gain as well as low noise figure, the circuit uses… More >

  • Open Access

    ARTICLE

    Optimal Building Frame Column Design Based on the Genetic Algorithm

    Tao Shen1,*, Yukari Nagai1, Chan Gao2

    CMC-Computers, Materials & Continua, Vol.58, No.3, pp. 641-651, 2019, DOI:10.32604/cmc.2019.04885

    Abstract Building structure is like the skeleton of the building, it bears the effects of various forces and forms a supporting system, which is the material basis on which the building depends. Hence building structure design is a vital part in architecture design, architects often explore novel applications of their technologies for building structure innovation. However, such searches relied on experiences, expertise or gut feeling. In this paper, a new design method for the optimal building frame column design based on the genetic algorithm is proposed. First of all, in order to construct the optimal model More >

  • Open Access

    ARTICLE

    Delay-dependent Stability of Recurrent Neural Networks with Time-varying Delay

    Guobao Zhanga,b, Jing-Jing Xionga,b, Yongming Huanga,b, Yong Lua,b,c, Ling Wanga,b

    Intelligent Automation & Soft Computing, Vol.24, No.3, pp. 541-551, 2018, DOI:10.31209/2018.100000021

    Abstract This paper investigates the delay-dependent stability problem of recurrent neural networks with time-varying delay. A new and less conservative stability criterion is derived through constructing a new augmented Lyapunov-Krasovskii functional (LKF) and employing the linear matrix inequality method. A new augmented LKF that considers more information of the slope of neuron activation functions is developed for further reducing the conservatism of stability results. To deal with the derivative of the LKF, several commonly used techniques, including the integral inequality, reciprocally convex combination, and free-weighting matrix method, are applied. Moreover, it is found that the obtained More >

  • Open Access

    ARTICLE

    The 745.5 issue in code-based, adult congenital heart disease population studies: Relevance to current and future ICD-9-CM and ICD-10-CM studies

    Fred H. Rodriguez III1,2,3,4, Georges Ephrem1,2, Jennifer F. Gerardin1,2, Cheryl Raskind-Hood5, Carol Hogue5, Wendy Book1,2

    Congenital Heart Disease, Vol.13, No.1, pp. 59-64, 2018, DOI:10.1111/chd.12563

    Abstract Objective: Although the ICD-9-CM code 745.5 is widely used to indicate the presence of a secundum atrial septal defect (ASD), it is also used for patent foramen ovale (PFO) which is a normal variant and for “rule-out” congenital heart disease (CHD). The ICD-10-CM code Q21.1 perpetuates this issue. The objective of this study was to assess whether code 745.5 in isolation or in combination with unspecified CHD codes 746.9 or 746.89 miscodes for CHD, and if true CHD positives decrease with age.
    Design: Echocardiograms of patients with an ICD-9-CM code of 745.5 in isolation or in combination… More >

  • Open Access

    EDITORIAL

    Preface: Innovations and Current Trends in Computational Cardiovascular Modeling and Beyond: Molecular, Cellular, Tissue and Organ Biomechanics with Clinical Applications

    Dalin Tang1,2,*, Zhiyong Li1

    CMES-Computer Modeling in Engineering & Sciences, Vol.116, No.2, pp. 109-113, 2018, DOI:10.31614/cmes.2018.04201

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Eddy Current Analyses by Domain Decomposition Method Using Double-Double Precision

    Mizuma Takehito1,*, Takei Amane1

    CMES-Computer Modeling in Engineering & Sciences, Vol.116, No.3, pp. 349-363, 2018, DOI:10.31614/cmes.2018.01714

    Abstract A matrix equation solved in an eddy current analysis, A-ϕ method based on a domain decomposition method becomes a complex symmetric system. In general, iterative method is used as the solver. Convergence of iterative method in an interface problem is improved by increasing an accuracy of a solution of an iterative method of a subdomain problem. However, it is difficult to improve the convergence by using a small convergence criterion in the subdomain problem. Therefore, authors propose a method to introduce double-double precision into the interface problem and the subdomain problem. This proposed method improves More >

  • Open Access

    REVIEW

    What is the current role of partial nephrectomy for T2 tumors?

    Bruno Nahar, Mark L. Gonzalgo

    Canadian Journal of Urology, Vol.24, No.2, pp. 8698-8704, 2017

    Abstract Introduction: To review oncological and functional outcomes for partial nephrectomy in the setting of T2 tumors.
    Materials and methods: We performed a comprehensive literature review on partial nephrectomy for T2 tumors, focusing on major primary series reporting oncological and functional outcomes, as well as complication rates in the last 10 years.
    Results: Recent series have reported comparable oncological outcomes between partial nephrectomy and radical nephrectomy for ≥ T2 tumors. However, most of these studies are retrospective in design with small sample sizes. With regard to functional outcomes, partial nephrectomy outperforms radical nephrectomy. However, outcomes are dependent on the… More >

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