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  • Open Access

    ARTICLE

    Voxel-based Analysis of Electrostatic Fields in Virtual-human Model Duke using Indirect Boundary Element Method with Fast Multipole Method

    S. Hamada1

    CMES-Computer Modeling in Engineering & Sciences, Vol.102, No.5, pp. 407-424, 2014, DOI:10.3970/cmes.2014.102.407

    Abstract The voxel-based indirect boundary element method (IBEM) combined with the Laplace-kernel fast multipole method (FMM) is capable of analyzing relatively large-scale problems. A typical application of the IBEM is the electric field analysis in virtual-human models such as the model called Duke provided by the foundation for research on information technologies in society (IT’IS Foundation). An important property of voxel-version Duke models is that they have various voxel sizes but the same structural feature. This property is useful for examining the O(N) and O(D2) dependencies of the calculation times and the amount of memory required by More >

  • Open Access

    ARTICLE

    Lactobacillus for preventing recurrent urinary tract infections in women: meta-analysis

    Peter M. Grin1,2, Paulina M. Kowalewska3, Waleed Alhazzani1, Alison E. Fox-Robichaud1,2

    Canadian Journal of Urology, Vol.20, No.1, pp. 6607-6614, 2013

    Abstract Introduction: Urinary tract infections (UTIs) are the most common infections affecting women, and often recur. Lactobacillus probiotics could potentially replace low dose, long term antibiotics as a safer prophylactic for recurrent UTI (rUTI). This systematic review and meta-analysis was performed to compile the results of existing randomized clinical trials (RCTs) to determine the efficacy of probiotic Lactobacillus species in preventing rUTI.
    Materials and methods: MEDLINE and EMBASE were searched from inception to July 2012 for RCTs using a Lactobacillus prophylactic against rUTI in premenopausal adult women. A random-effects model meta-analysis was performed using a pooled risk ratio,… More >

  • Open Access

    ARTICLE

    Percutaneous cryoablation for recurrent low grade renal cell carcinoma after failed nephron-sparing surgery

    Matthew A. Morgan1, Nathan R. Roberts2, Laura A. Pino1, Edouard J. Trabulsi2,3, Daniel B. Brown1,3, Leonard G. Gomella2,3, Costas D. Lallas2,3

    Canadian Journal of Urology, Vol.20, No.5, pp. 6933-6937, 2013

    Abstract Introduction: Partial nephrectomy has a 3%-4% incidence of local treatment failure. This study is to present a series of percutaneous cryoablation for locally recurrent renal cell carcinoma after partial nephrectomy.
    Materials and methods: Five consecutive patients were referred to our quaternary center’s multidisciplinary Small Renal Mass (SRM) Center for assessment after failure of partial nephrectomy. Tumor size and location was noted. CT-guided cryoablation was performed using an argon/helium-based system (Healthtronics, Austin, Texas, USA). Patients were admitted overnight for observation. Patients were followed with serial imaging, laboratory tests and examination at our SRM Center. Tumor size, location, and… More >

  • Open Access

    REVIEW

    Ureteral diverticulum: a review of the current literature

    Louise C. McLoughlin, Niall F. Davis, Catherine Dowling, Molly P. Eng, Richard E. Power

    Canadian Journal of Urology, Vol.20, No.5, pp. 6893-6896, 2013

    Abstract Introduction: Ureteral diverticulum is a rare urological condition with only 45 cases described in the literature. These previously reported cases vary in their presentation, diagnosis and management and there is no consensus in the literature on the best diagnostic tool available. We describe our experience on diagnosing and managing this condition in two patients and provide a descriptive review of the current literature on ureteral diverticulum.
    Materials and methods: A Medline search was performed to identify all reported cases of ureteral diverticulum. Key words used were: ureteral diverticulum; abortive bifid ureter; congenital diverticulum; acquired diverticulum. We also… More >

  • Open Access

    ARTICLE

    Rigid Biobased Building Blocks: Current Developments and Outlook

    Daan S. van Es

    Journal of Renewable Materials, Vol.1, No.1, pp. 61-72, 2013, DOI:10.7569/JRM.2012.634108

    Abstract In this perspectives paper we will look at the state-of-the-art in rigid renewable building blocks for biobased materials, with a focus on two types of carbohydrate-based difunctional monomers, i.e.,isohexides and furan- 2,5-dicarboxylic acid (FDCA). More >

  • Open Access

    REVIEW

    The current role of percutaneous biopsy of renal masses

    Abhijith Dev Mally, Bishoy Gayed, Timothy Averch, Benjamin Davies

    Canadian Journal of Urology, Vol.19, No.3, pp. 6243-6249, 2012

    Abstract Introduction: There has been an increased incidence of small renal masses with a majority incidentally discovered in elderly patients or patients with several comorbidities. The historic role of renal biopsy has been limited due to initial concerns about accuracy and safety. This review analyses the current role of percutaneous renal biopsy.
    Materials and methods: A comprehensive literature review of PubMed and MEDLINE for reports of percutaneous needle core biopsy and fine needle aspiration of renal tumors that were published from 1977 to 2012.
    Results: With the adoption of new biopsy techniques, there is a very low risk of… More >

  • Open Access

    REVIEW

    Salvage therapy for locally recurrent prostate cancer after radiation

    David M. Marcus1,5, Daniel J. Canter2,5, Ashesh B. Jani1,2,5, Ryan W. Dobbs2, David M. Schuster3, Bradley C. Carthon4,5, Peter J. Rossi1,2,5

    Canadian Journal of Urology, Vol.19, No.6, pp. 6534-6541, 2012

    Abstract Introduction: External beam radiotherapy (EBRT) is widely utilized as primary therapy for clinically localized prostate cancer. For patients who develop locally recurrent disease after EBRT, local salvage therapy may be indicated. The primary modalities for local salvage treatment in this setting include radical prostatectomy, cryotherapy, and brachytherapy. To date, there is little data describing outcomes and toxicity associated with each of these salvage modalities.
    Materials and methods: A review of the literature was performed to identify studies of local salvage therapy for patients who had failed primary EBRT for localized prostate cancer. We focused on prospective trials… More >

  • Open Access

    ARTICLE

    Genetic variations in the interleukin-21 gene and the risk of recurrent idiopathic spontaneous miscarriage

    Safia Messaoudi1, Ghada M. Al-Khateeb2, Maryam Dendana1, Mai S. Sater2, Khaled B. Jazia3, Mounia Nouira4, Wassim Y. Almawi2, Touhami Mahjoub1

    European Cytokine Network, Vol.22, No.2, pp. 123-126, 2011, DOI:10.1684/ecn.2011.0287

    Abstract Objectives. Insofar as recurrent spontaneous miscarriage (RSM) is linked with dysregulated immunity and inflammatory changes, and given the pro-inflammatory role of interleukin-21 (IL-21), we examined the association between IL-21 polymorphisms and RSM. Methods and results. IL-21 rs2055979, rs13143866, rs9992580, and rs4833837 were genotyped in 235 cases of RSM and 235 controls. Regression analysis was employed in assessing the contribution of IL-21 variants to the overall RSM risk. Higher minor allele and genotype frequencies of rs2055979 and rs13143866, but not rs9992580 or rs4833837, were seen in RSM patients than in the controls. IL-21 haplotype [rs9992580/rs4833837/rs2055979/rs13143866] analysis More >

  • Open Access

    RESIDENT’S CORNER

    Presentation of bladder leiomyoma concurrent with transitional cell carcinoma

    Zurab Davili1, Zahi Makhuli1, Christopher Hartman1, Rong Rong2

    Canadian Journal of Urology, Vol.18, No.1, pp. 5560-5563, 2011

    Abstract We report a case of a 46-year-old male who presented to the outpatient urology clinic with an incidental bladder mass. Office cystoscopy revealed two synchronous tumors of different morphology. Endoscopic resection was performed to remove the smaller, papillary tumor, of which pathology revealed Ta, Grade 1 urothelial carcinoma. A second open resection was performed to remove the second tumor, a benign leiomyoma. More >

  • Open Access

    REVIEW

    Current status of pelvic lymph node dissection in prostate cancer: the New York PLND nomogram

    Amir Kazzazi, Bob Djavan

    Canadian Journal of Urology, Vol.18, No.2, pp. 5585-5591, 2011

    Abstract Introduction: Controversy persists concerning the role of pelvic lymph node dissection (PLND) in patients with clinically localized prostate cancer undergoing radical prostatectomy. The aim of this review is to critically evaluate the current status on PLND in prostate cancer.
    Methods: A review of the literature was performed concerning radical prostatectomy and PLND with respect to oncological outcome, associated complications, nodal yield, indications and minimal number of nodes required.
    Results: PLND is still the modality of choice for detecting lymph node metastasis in prostate cancer. Current imaging techniques are not accurate enough for detecting nodal metastases. Extended PLND has… More >

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