Leonard G. Gomella1, Xiaolong S. Liu1, Edouard J. Trabulsi1, Wm. Kevin Kelly2, Ronald Myers2, Timothy Showalter3, Adam Dicker3, Richard Wender4
Canadian Journal of Urology, Vol.18, No.5, pp. 5875-5883, 2011
Abstract Introduction: Prostate cancer presents a global public health dilemma. While screening with prostate specific antigen (PSA) has led to more men diagnosed with prostate cancer than in previous years, the potential for negative effects from over-diagnosis and treatment cannot be ignored.
Materials and methods: We reviewed Medline for recent articles that discuss clinical trials, evidence based recommendations and guidelines from major medical organizations in the United States and worldwide concerning prostate cancer screening.
Results: Results from the European Randomized Screening for Prostate Cancer (ERSPC), the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, and Göteborg Swedish trials… More >