Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (125)
  • Open Access

    REVIEW

    The role of mesenchymal stem cell-derived exosomes in tumor progression

    CARL RANDALL HARREL1, VALENTIN DJONOV2, ANA VOLAREVIC3, DRAGICA PAVLOVIC4, VLADISLAV VOLAREVIC4,5,*

    BIOCELL, Vol.47, No.8, pp. 1757-1769, 2023, DOI:10.32604/biocell.2023.028567

    Abstract Exosomes derived from mesenchymal stem cells (MSC-Exos) are nano-sized extracellular vesicles enriched with bioactive molecules, such as microRNAs, enzymes, cytokines, chemokines, immunomodulatory, trophic, and growth factors. These molecules regulate the survival, phenotype, and function of malignant and tumor-infiltrated immune cells. Due to their nano-size and bilayer lipid envelope, MSC-Exos can easily bypass biological barriers and may serve as drug carriers to deliver chemotherapeutics directly into the tumor cells. Here, we summarize current knowledge regarding molecular mechanisms responsible for MSC-Exos-dependent modulation of tumor progression and discuss insights regarding the therapeutic potential of MSC-Exos in the treatment of malignant diseases. More > Graphic Abstract

    The role of mesenchymal stem cell-derived exosomes in tumor progression

  • Open Access

    ARTICLE

    Multi Head Deep Neural Network Prediction Methodology for High-Risk Cardiovascular Disease on Diabetes Mellitus

    B. Ramesh, Kuruva Lakshmanna*

    CMES-Computer Modeling in Engineering & Sciences, Vol.137, No.3, pp. 2513-2528, 2023, DOI:10.32604/cmes.2023.028944

    Abstract Major chronic diseases such as Cardiovascular Disease (CVD), diabetes, and cancer impose a significant burden on people and healthcare systems around the globe. Recently, Deep Learning (DL) has shown great potential for the development of intelligent mobile Health (mHealth) interventions for chronic diseases that could revolutionize the delivery of health care anytime, anywhere. The aim of this study is to present a systematic review of studies that have used DL based on mHealth data for the diagnosis, prognosis, management, and treatment of major chronic diseases and advance our understanding of the progress made in this rapidly developing field. Type 2… More > Graphic Abstract

    Multi Head Deep Neural Network Prediction Methodology for High-Risk Cardiovascular Disease on Diabetes Mellitus

  • Open Access

    ARTICLE

    Towards Intelligent Detection and Classification of Rice Plant Diseases Based on Leaf Image Dataset

    Fawad Ali Shah1, Habib Akbar1, Abid Ali2,3, Parveen Amna4, Maha Aljohani5, Eman A. Aldhahri6, Harun Jamil7,*

    Computer Systems Science and Engineering, Vol.47, No.2, pp. 1385-1413, 2023, DOI:10.32604/csse.2023.036144

    Abstract The detection of rice leaf disease is significant because, as an agricultural and rice exporter country, Pakistan needs to advance in production and lower the risk of diseases. In this rapid globalization era, information technology has increased. A sensing system is mandatory to detect rice diseases using Artificial Intelligence (AI). It is being adopted in all medical and plant sciences fields to access and measure the accuracy of results and detection while lowering the risk of diseases. Deep Neural Network (DNN) is a novel technique that will help detect disease present on a rice leave because DNN is also considered… More >

  • Open Access

    ARTICLE

    Deep Transfer Learning Based Detection and Classification of Citrus Plant Diseases

    Shah Faisal1, Kashif Javed1, Sara Ali1, Areej Alasiry2, Mehrez Marzougui2, Muhammad Attique Khan3,*, Jae-Hyuk Cha4,*

    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 895-914, 2023, DOI:10.32604/cmc.2023.039781

    Abstract Citrus fruit crops are among the world’s most important agricultural products, but pests and diseases impact their cultivation, resulting in yield and quality losses. Computer vision and machine learning have been widely used to detect and classify plant diseases over the last decade, allowing for early disease detection and improving agricultural production. This paper presented an automatic system for the early detection and classification of citrus plant diseases based on a deep learning (DL) model, which improved accuracy while decreasing computational complexity. The most recent transfer learning-based models were applied to the Citrus Plant Dataset to improve classification accuracy. Using… More >

  • Open Access

    ARTICLE

    Spatial Correlation Module for Classification of Multi-Label Ocular Diseases Using Color Fundus Images

    Ali Haider Khan1,2,*, Hassaan Malik2, Wajeeha Khalil3, Sayyid Kamran Hussain4, Tayyaba Anees5, Muzammil Hussain2

    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 133-150, 2023, DOI:10.32604/cmc.2023.039518

    Abstract To prevent irreversible damage to one’s eyesight, ocular diseases (ODs) need to be recognized and treated immediately. Color fundus imaging (CFI) is a screening technology that is both effective and economical. According to CFIs, the early stages of the disease are characterized by a paucity of observable symptoms, which necessitates the prompt creation of automated and robust diagnostic algorithms. The traditional research focuses on image-level diagnostics that attend to the left and right eyes in isolation without making use of pertinent correlation data between the two sets of eyes. In addition, they usually only target one or a few different… More >

  • Open Access

    ARTICLE

    Medical Image Fusion Based on Anisotropic Diffusion and Non-Subsampled Contourlet Transform

    Bhawna Goyal1,*, Ayush Dogra2, Rahul Khoond1, Dawa Chyophel Lepcha1, Vishal Goyal3, Steven L. Fernandes4

    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 311-327, 2023, DOI:10.32604/cmc.2023.038398

    Abstract The synthesis of visual information from multiple medical imaging inputs to a single fused image without any loss of detail and distortion is known as multimodal medical image fusion. It improves the quality of biomedical images by preserving detailed features to advance the clinical utility of medical imaging meant for the analysis and treatment of medical disorders. This study develops a novel approach to fuse multimodal medical images utilizing anisotropic diffusion (AD) and non-subsampled contourlet transform (NSCT). First, the method employs anisotropic diffusion for decomposing input images to their base and detail layers to coarsely split two features of input… More >

  • Open Access

    ARTICLE

    Plant Leaf Diseases Classification Using Improved K-Means Clustering and SVM Algorithm for Segmentation

    Mona Jamjoom1, Ahmed Elhadad2, Hussein Abulkasim3,*, Safia Abbas4

    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 367-382, 2023, DOI:10.32604/cmc.2023.037310

    Abstract Several pests feed on leaves, stems, bases, and the entire plant, causing plant illnesses. As a result, it is vital to identify and eliminate the disease before causing any damage to plants. Manually detecting plant disease and treating it is pretty challenging in this period. Image processing is employed to detect plant disease since it requires much effort and an extended processing period. The main goal of this study is to discover the disease that affects the plants by creating an image processing system that can recognize and classify four different forms of plant diseases, including Phytophthora infestans, Fusarium graminearum,… More >

  • Open Access

    ARTICLE

    Image Generation of Tomato Leaf Disease Identification Based on Small-ACGAN

    Huaxin Zhou1,2, Ziying Fang3, Yilin Wang4, Mengjun Tong1,2,*

    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 175-194, 2023, DOI:10.32604/cmc.2023.037342

    Abstract Plant diseases have become a challenging threat in the agricultural field. Various learning approaches for plant disease detection and classification have been adopted to detect and diagnose these diseases early. However, deep learning entails extensive data for training, and it may be challenging to collect plant datasets. Even though plant datasets can be collected, they may be uneven in quantity. As a result, the problem of classification model overfitting arises. This study targets this issue and proposes an auxiliary classifier GAN (small-ACGAN) model based on a small number of datasets to extend the available data. First, after comparing various attention… More >

  • Open Access

    ARTICLE

    Statistical Time Series Forecasting Models for Pandemic Prediction

    Ahmed ElShafee1, Walid El-Shafai2,3, Abeer D. Algarni4,*, Naglaa F. Soliman4, Moustafa H. Aly5

    Computer Systems Science and Engineering, Vol.47, No.1, pp. 349-374, 2023, DOI:10.32604/csse.2023.037408

    Abstract COVID-19 has significantly impacted the growth prediction of a pandemic, and it is critical in determining how to battle and track the disease progression. In this case, COVID-19 data is a time-series dataset that can be projected using different methodologies. Thus, this work aims to gauge the spread of the outbreak severity over time. Furthermore, data analytics and Machine Learning (ML) techniques are employed to gain a broader understanding of virus infections. We have simulated, adjusted, and fitted several statistical time-series forecasting models, linear ML models, and nonlinear ML models. Examples of these models are Logistic Regression, Lasso, Ridge, ElasticNet,… More >

  • Open Access

    ARTICLE

    Probability Based Regression Analysis for the Prediction of Cardiovascular Diseases

    Wasif Akbar1, Adbul Mannan2, Qaisar Shaheen3,*, Mohammad Hijji4, Muhammad Anwar5, Muhammad Ayaz6

    CMC-Computers, Materials & Continua, Vol.75, No.3, pp. 6269-6286, 2023, DOI:10.32604/cmc.2023.036141

    Abstract Machine Learning (ML) has changed clinical diagnostic procedures drastically. Especially in Cardiovascular Diseases (CVD), the use of ML is indispensable to reducing human errors. Enormous studies focused on disease prediction but depending on multiple parameters, further investigations are required to upgrade the clinical procedures. Multi-layered implementation of ML also called Deep Learning (DL) has unfolded new horizons in the field of clinical diagnostics. DL formulates reliable accuracy with big datasets but the reverse is the case with small datasets. This paper proposed a novel method that deals with the issue of less data dimensionality. Inspired by the regression analysis, the… More >

Displaying 21-30 on page 3 of 125. Per Page