J. E. Sebold¹, L. A. Lacerda², J. A. M. Carrer³

CMES-Computer Modeling in Engineering & Sciences, Vol.103, No.2, pp. 111-137, 2014, DOI:10.3970/cmes.2014.103.111

Abstract This work is concerned with the development of the so-called Whitney and Nédélec edge finite element method for the solution of the time-harmonic Maxwell equations. Initially, the second order time harmonic Maxwell systems, as well as their variational formulation, are presented. In the sequence, Whitney and Nédélec element spaces, whose functions present continuous tangential components along the interface are built of adjacent elements. Then, numerical experiments validate the performance of Whitney and Nédélec first order elements in a two-dimensional domain. The discrete dispersion relation for the elements shows that the numerical phase velocity can be More >

S,erson L. Gonzaga de Oliveira¹, Jéssica Renata Nogueira¹, João Manuel R. S. Tavares²

CMES-Computer Modeling in Engineering & Sciences, Vol.100, No.1, pp. 31-57, 2014, DOI:10.3970/cmes.2014.100.031

Abstract Triangulations and tetrahedrizations are important geometrical discretization procedures applied to several areas, such as the reconstruction of surfaces and data visualization. Delaunay and Voronoi tessellations are discretization structures of domains with desirable geometrical properties. In this work, a systematic review of algorithms with linear-time behaviour to generate 2D/3D Delaunay and/or Voronoi tessellations is presented. More >

Andrea Morelli, Dario Puppi, Federica Chiellini^*

Journal of Renewable Materials, Vol.1, No.2, pp. 83-112, 2013, DOI:10.7569/JRM.2012.634106

Abstract Polymers, particularly those susceptible to undergoing biodegradation under physiological environments, can be considered the materials of choice for biomedical applications such as tissue engineering, regenerative medicine, and controlled and targeted drug delivery. The development of these relatively new fi elds of biomedical research represents the driving force towards the exploitation of renewable resources for the obtainment of biobased polymeric biomaterials. This perspective article reports on the biomedical applications of three major categories of biobased polymeric materials obtained from renewable resources, namely, polysaccharides, proteins and polyesters of natural origins. Particular emphasis is given to biobased polymers More >

Idalba A. Hidalgo A.^∗, Felipe Sojo^†, Francisco Arvelo^†, Marcos A. Sabino^∗,‡

Molecular & Cellular Biomechanics, Vol.10, No.2, pp. 85-105, 2013, DOI:10.3970/mcb.2013.010.085

Abstract The electrospinning technique is a method used to produce nano and microfibers using the influence of electrostatic forces. Porous three dimensional networks of continuous and interconnected fibers as scaffolds were obtained from a poly (lactic acid) solution. The concentration of the polymeric solution, 12.5% m/w, as well as the conditions of voltage (V=11kV) and tip-metallic collector distance (H=13cm) were established to develop these scaffolds through the electrospinning process. The characteristics of the scaffolds, such as fiber diameter, sintering and the biomimetics of the characteristics of a native extra cellular matrix were verified by Scanning Electron More >

J. Sladek¹, P. Stanak¹, Z-D. Han², V. Sladek¹, S.N. Atluri²

CMES-Computer Modeling in Engineering & Sciences, Vol.92, No.5, pp. 423-475, 2013, DOI:10.3970/cmes.2013.092.423

Abstract A review is presented for analysis of problems in engineering & the sciences, with the use of the meshless local Petrov-Galerkin (MLPG) method. The success of the meshless methods lie in the local nature, as well as higher order continuity, of the trial function approximations, high adaptivity and a low cost to prepare input data for numerical analyses, since the creation of a finite element mesh is not required. There is a broad variety of meshless methods available today; however the focus is placed on the MLPG method, in this paper. The MLPG method is… More >

Mohammad Izadifar^a,b,*, Xiongbiao Chen^a,b

Frontiers in Heat and Mass Transfer, Vol.3, No.4, pp. 1-7, 2012, DOI:10.5098/hmt.v3.4.3004

Abstract Heat can be potentially used for accelerating biodegradation of implanted tissue engineered scaffolds. Cyclic and continuous radio frequency (RF) heating was applied to implanted chitosan and alginate scaffolds at 4 applied voltages, 3 frequencies, and 2 thermally conditioning environments. A 3D finite element model was developed to simulate the RF treatment. A uniform RF heating was achieved at the scaffold top. For alginate, voltage was the only significant RF heating factor while both frequency and voltage significantly affected RF heating of chitosan. Less temperature gradient across the scaffold was achieved at a conditioning environment at More >

BIOCELL, Vol.36, Suppl.S, pp. 1-14, 2012

Abstract This article has no abstract. More >

RANA IMANI¹, SHAHRIAR HOJJATI EMAMI¹, HOSSEIN FAKHRZADEH², NAFISEH BAHEIRAEI¹, ALI M SHARIFI^{* 2,3,4}

BIOCELL, Vol.36, No.1, pp. 37-45, 2012, DOI:10.32604/biocell.2012.36.037

Abstract The ultimate goal of tissue engineering is to design and fabricate functional human tissues that are similar to natural cells and are capable of regeneration. Preparation of cell aggregates is one of the important steps in 3D tissue engineering technology, particularly in organ printing. Two simple methods, hanging drop (HD) and conical tube (CT) were utilized to prepare cell aggregates. The size and viability of the aggregates obtained at different initial cell densities and pre-culture duration were compared. The proliferative ability of the cell aggregates and their ability to spread in culture plates were also… More >

Deli Gao¹, Zhen Dong¹, Hui Zhang¹

CMES-Computer Modeling in Engineering & Sciences, Vol.89, No.2, pp. 111-122, 2012, DOI:10.3970/cmes.2012.089.111

Abstract The bottom hole pendulum assembly is a type of bottom hole assembly (BHA) for controlling the hole deviation, and has been widely used in drilling engineering. Generally, the ability of the drill bit to penetrate laterally, is different from its ability to penetrate axially, so that the drill bit has an anisotropy which affects the hole-deviation-control characteristics of the BHA. The tilt angle and the side force of the drill bit are obtained by a BHA analysis based on the method of weighted residuals. Thus, the effective drilling force can be determined using the rock-bit… More >

R. Khanna^1,2, D. R. Katti¹, K. S. Katti¹

CMES-Computer Modeling in Engineering & Sciences, Vol.87, No.6, pp. 530-556, 2012, DOI:10.3970/cmes.2012.087.530

Abstract Here we report a new in situ nanoindentation technique developed to evaluate the composite mechanical behavior of cell-biomaterial construct under physiological conditions over the time scale of bone nodule generation. Using this technique, mechanical behavior of osteoblast cell-substrate interfaces on tissue engineered materials (chitosan-polygalacturonic acid-nanohydroxyapatite (CPH) films) is investigated. Mechanical behavior of cells in the elastic regime over the time scale of cell adhesion (1 day), proliferation (4 days), development (8 days) and maturation (22 days) of bone nodules is evaluated. Our results indicate that the elastic properties of flat cells are higher (indicating stiffer… More >