K.W. Luczynski¹, A. Dejaco¹, O. Lahayne¹, J. Jaroszewicz², W.Swieszkowski², C. Hellmich¹

CMES-Computer Modeling in Engineering & Sciences, Vol.87, No.6, pp. 505-529, 2012, DOI:10.3970/cmes.2012.087.505

Abstract A 71 volume-% macroporous tissue engineering scaffold made of poly-l-lactide (PLLA) with 10 mass-% of pseudo-spherical tri-calcium phosphate (TCP) inclusions (exhibiting diameters in the range of several nanometers) was microCT-scanned. The corresponding stack of images was converted into regular Finite Element (FE) models consisting of around 100,000 to 1,000,000 finite elements. Therefore, the attenuation-related, voxel-specific grey values were converted into TCP-contents, and the latter, together with nanoindentation tests,entered a homogenization scheme of the Mori-Tanaka type, as to deliver voxel-specific (and hence, finite element-specific) elastic properties. These FE models were uniaxially loaded, giving access to the… More >

G. Mattei^1,2, A. Tirella^1,2, A. Ahluwalia^1,2

CMES-Computer Modeling in Engineering & Sciences, Vol.87, No.6, pp. 483-504, 2012, DOI:10.3970/cmes.2012.087.483

Abstract Biological function is intricately linked with structure. Many biological structures are characterised by functional spatially distributed gradients in which each layer has one or more specific functions to perform. Reproducing such structures is challenging, and usually an experimental trial-and-error approach is used. In this paper we investigate how the gravitational sedimentation of discrete solid particles (secondary phase) within a primary fluid phase with a time-varying dynamic viscosity can be used for the realisation of stable and reproducible continuous functionally graded materials (FGMs). Computational models were used to simulate the distribution of a particle phase in… More >

T. Fu, C.P. Wang, B. Hou, X.D. Zhu, Z.F. Zhou, K.Y. Li, J. Lu

The International Conference on Computational & Experimental Engineering and Sciences, Vol.20, No.3, pp. 91-92, 2011, DOI:10.3970/icces.2011.020.091

Abstract Structural steels are widely used in engineering fields. Generally, they have the advantage of lower prices due to less precious alloy elements contained; however, their properties, especially the surface properties are inferior to high alloy steels. Surface engineering are of importance in improving surface properties of steels, and even a 'new' surface layer with high performances can be produced by surface technologies on low cost structural steels with ordinary properties.
The researches of last decade have shown that surface nanocrystallization (SNC) can markedly improve surface mechanical properties of metallic materials and accelerate thermal diffusion of N,… More >

Hana Chang^*, Melissa L. Knothe Tate^∗,†,‡

Molecular & Cellular Biomechanics, Vol.8, No.4, pp. 297-318, 2011, DOI:10.3970/mcb.2011.008.297

Abstract In the preceding study (Part A), we showed that prescribed seeding conditions as well as seeding density can be used to subject multipotent stem cells (MSCs) to volume changing stresses and that changes in volume of the cell are associated with changes in shape, but not volume, of the cell nucleus. In the current study, we aim to control the mechanical milieu of live cells using these prescribed seeding conditions concomitant to delivery of shape changing stresses via fluid flow, while observing adaptation of the cytoskeleton, a major cellular transducer that modulates cell shape, stiffness… More >

Joshua A. Zimmermann^*, Melissa L. Knothe Tate^∗,†,‡

Molecular & Cellular Biomechanics, Vol.8, No.4, pp. 275-296, 2011, DOI:10.3970/mcb.2011.008.275

Abstract Shape and fate are intrinsic manifestations of form and function at the cell scale. Here we hypothesize that seeding density and protocol affect the form and function of live embryonic murine mesenchymal stem cells (MSCs) and their nuclei. First, the imperative for study of live cells was demonstrated in studies showing changes in cell nucleus shape that were attributable to fixation per se. Hence, we compared live cell and nuclear volume and shape between groups of a model MSC line (C3H10T1/2) seeded at, or proliferated from 5,000 cells/cm2 to one of three target densities to… More >

Ziya Aktas¹, Semih Cetin²

CMES-Computer Modeling in Engineering & Sciences, Vol.76, No.2, pp. 133-162, 2011, DOI:10.3970/cmes.2011.076.133

Abstract The knowledge society has been developed and shaped by amazing improvements during the last two decades. On that development and improvement, social sciences such as psychology or anthropology have also had significant impact as much as real sciences like medicine or engineering, in particular, Information Technology or Information and Communications Technology. The new trends and explosion of knowledge due to Internet and Web technologies have radically changed the way we structure business and its main building block, i.e. "knowledge". Though information/knowledge system development efforts have been regarded formerly as mere information technology activities, now we… More >

A. Gakwaya¹, H. Sharifi², M. Guillot¹, M. Souli³, F. Erchiqui⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.73, No.3, pp. 209-266, 2011, DOI:10.3970/cmes.2011.073.209

Abstract A mechanical computer aided design and engineering system can be used to reduce the design-to-manufacture cycle time in metal forming process. Such a system could be built upon a solid modeling geometry engine and an efficient finite element (FE) solver. The maintenance of a high-quality mesh throughout the analysis is an essential feature of an efficient finite element simulation of large strain metal forming problems. In this paper, a mesh adaptation technique employing the Arbitrary Lagrangian-Eulerian formulation (ALE) is applied to some industrial metal forming problems. An ACIS boundary representation of the solid model is… More >

P.D.Gosling^1,2, L. Zhang²

CMES-Computer Modeling in Engineering & Sciences, Vol.71, No.3, pp. 203-252, 2011, DOI:10.3970/cmes.2011.071.203

Abstract The analysis of a continuum membrane by means of a discrete network of cables or bars is an efficient and readily tractable approach to the solution of a complex mechanics problem. However, is so doing, compromises are made in the quality of the approximation of the strain field. It is shown in this paper that the original form of the cable-analogy continuum triangle formulation is degraded by an inherent assumption of small strains in the underlying equations, in which the term ßmall" is shown to be "negligibly small". A revised version of this formulation is… More >

A.A.Bayramov¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.15, No.1, pp. 19-26, 2010, DOI:10.3970/icces.2010.015.019

Abstract As we know, anthropogenic activities of Power Engineering create wastewater and air pollution, lead to aerosol attenuation of solar radiation and to growth of entropy on the Earth and, as result, climate change. The human Power activities disturb heat and entropy balance and impair ecology. Also, this leads to greenhouse effect and, as result, to climate change. Wastewater in river and sea basins as well as air pollution can influence an exchange of energy between sunlight on the Earth and long-wave radiation leaving in space.
In the paper the role of nanomaterials pollution in Power Engineering More >

M.K. Kang¹, E.H. Kim¹, M.S. Rim¹, I. Lee^1,2

CMES-Computer Modeling in Engineering & Sciences, Vol.64, No.3, pp. 227-250, 2010, DOI:10.3970/cmes.2010.064.227

Abstract An engineering model for predicting the behavior of shape memory alloy (SMA) wire is presented in this study. Piecewise linear relations between stress and strain at a given temperature are assumed and the mixture rule of Reuss bounds is applied to get the elastic modulus of the SMAs in the mixed phase. Critical stresses and strains of the start and finish of the phase transformation are calculated at a given temperature by means of a linear constitutive equation and a stress-temperature diagram. Transformation conditions based on the critical stresses are translated in terms of critical More >