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    Comprehensive Network Analysis of the Molecular Regulation Mechanism for Breast Cancer Metastasis

    Shaoguan Huang1, Rong Zhang2, Lizhen Liu3,*

    Oncologie, Vol.23, No.1, pp. 159-171, 2021, DOI:10.32604/Oncologie.2021.012489

    Abstract Breast cancer is one of malignant severe diseases that cause cancer death in women. Although research about the pathogenesis and studies about treatment mechanisms in breast cancer have become clear focuses, we have no clear conclusion yet. Therefore, this research is based on a modular approach to explore key factors and molecular mechanisms that affect breast cancer metastasis. First of all, it is necessary to download breast cancer-related data on the GEO database, and we analyzed the difference between primary tumors and metastatic lesions to obtain differential gene expression profiles. On this basis, a series of bioinformatics analyses were performed… More >

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