YANAN MA¹, SHANSHAN WANG^2,*, HUIGUO DING^1,*

BIOCELL, Vol.48, No.3, pp. 463-471, 2024, DOI:10.32604/biocell.2024.048244

Abstract Background: Hepatocellular carcinoma (HCC) is a common malignant tumor with poor prognosis and high mortality worldwide. Although cystathionine-gamma-lyase (CSE) plays an important role in the development of multiple tumors, the clinical implication and potential mechanisms of CSE in HCC development remain elusive. Methods: In our study, the CSE expression in HCC was analyzed in Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) datasets and further confirmed by RT-qPCR and immunohistochemistry assays in HCC samples. Furthermore, the associations between CSE expression and HCC malignancy as well as survival were analyzed in GSE14520 and validated in HCC patients. Finally, the… More >

PEI QIN^#, MIAO LIU^#, XIN WANG, JIANHUA MA^*

BIOCELL, Vol.48, No.3, pp. 513-523, 2024, DOI:10.32604/biocell.2023.045640

Abstract Background: L-dopa (Levodopa) is well known for managing PD (Parkinson’s disease); however, its prolonged use caused dyskinesia (LID). Due to the varied presentation of LID, effective treatment options are scarce. Flavonoids reported their neuroprotective activity by ameliorating acetylcholinesterase, monoamine oxidase, and neuroinflammation. Kaempferol is another flavonoid bearing these potentials. Aim: To evaluate neuroprotective activity of kaempferol in dyskinetic rats. Methods: PD was developed in Sprague-Dawley rats by injecting combination of L-ascorbic acid (10 µL) + 6-OHDA (12 µg) in medial forebrain bundle to induce neuronal damage in substantial nigra (SNr). LID was induced by administrating combination of L-dopa (20 mg/kg)… More > Graphic Abstract

Nikola Stosic^**, Ian K. Smith, Ahmed Kovacevic

Frontiers in Heat and Mass Transfer, Vol.3, No.2, pp. 1-7, 2012, DOI:10.5098/hmt.v3.2.3003

Abstract Due to fast rotation of screw compressor rotors, temperature is uniform in the rotor cross section and temperature field is a function of the axial coordinate only. Apart of that the rotors in one cross section the rotors are simultaneously heated by hot gas on one side while cooled at another side by cold gas. As a result of identification of the main modes of heat transfer both in the rotors and between the rotors and their surroundings and the relative significance of each, a novel procedure is suggested to cool the rotors by injection of minute quantities of a… More >

Frantisek Kavicka^a,*, Jana Dobrovska^b, Karel Stransky^a, Bohumil Sekanina^a, Josef Stetina^a

Frontiers in Heat and Mass Transfer, Vol.3, No.2, pp. 1-9, 2012, DOI:10.5098/hmt.v3.2.3002

Abstract Corundo-baddeleyit material (CBM) – EUCOR – is a heat- and wear-resistant material even at extreme temperatures. This article introduces an original numerical model of solidification and cooling of this material in a non-metallic mold. The second, cooperating model of chemical heterogeneity and its application on EUCOR samples prove that the applied method of measuring the chemical heterogeneity provides the detailed quantitative information on the material structure and makes it possible to analyze the solidification process. The verification of both numerical models was conducted on a real cast 350 x 200 x 400 mm block. More >

Milind S. Patil^a,*, Ramchandra S. Jahagirdar^b, Eknath R. Deore^a,†

Frontiers in Heat and Mass Transfer, Vol.3, No.3, pp. 1-5, 2012, DOI:10.5098/hmt.v3.3.3008

Abstract Convection heat loss inevitably occurs in receivers of high concentrating solar concentrators. All the concentrators are need to be tack during the operation and hence the position of the receiver is changing continually. The angle of the receiver axis will then play an important role in the heat loss. Few researches were reported for the hemispherical cavity receivers numerically. The paper presented here is an experimental investigation natural convection heat loss from hemispherical cavity receiver. Cavity receiver of diameter 540 mm was tested. It is observed that the heat loss was minimum for 90° and maximum for 0°. More >

Mohammad Izadifar^a,b,*, Xiongbiao Chen^a,b

Frontiers in Heat and Mass Transfer, Vol.3, No.4, pp. 1-7, 2012, DOI:10.5098/hmt.v3.4.3004

Abstract Heat can be potentially used for accelerating biodegradation of implanted tissue engineered scaffolds. Cyclic and continuous radio frequency (RF) heating was applied to implanted chitosan and alginate scaffolds at 4 applied voltages, 3 frequencies, and 2 thermally conditioning environments. A 3D finite element model was developed to simulate the RF treatment. A uniform RF heating was achieved at the scaffold top. For alginate, voltage was the only significant RF heating factor while both frequency and voltage significantly affected RF heating of chitosan. Less temperature gradient across the scaffold was achieved at a conditioning environment at <30°C. Surrounding tissue was insignificantly… More >

Deyong Shang^1,2, Xi Zhang¹, Fengqi Liang¹, Chunde Zhai¹, Hang Yang¹, Yanqi Niu^1,2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 2027-2041, 2024, DOI:10.32604/cmes.2023.045750

Abstract When the amphibious vehicle navigates in water, the angle of the anti-wave plate and the position of the center of gravity greatly influence the navigation characteristics. In the relevant research on reducing the navigation resistance of amphibious vehicles by adjusting the angle of the anti-wave plate, there is a lack of scientific selection of parameters and reasonable research of simulation results by using mathematical methods, and the influence of the center of gravity position on navigation characteristics is not considered at the same time. To study the influence of the combinations of the angle of the anti-wave plate and the… More >

Sheng Lan¹, Fei Yang^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.09077

Abstract Non-autoclaved concrete pipe piles are gaining attention as an environmentally friendly alternative to autoclaved concrete pipe piles. The purpose of this study was to investigate the changes in the impact resistance of a non-autoclaved concrete pipe pile with the addition of rubber. To this end, various volume fractions of rubber particles were used to replace the fine sand in the non-autoclaved pipe pile concrete (0%, 5%, 10% and 15%). Additionally, the axial impact resistance of rubber modified non-autoclaved concrete pipe pile was studied from the concrete materials and pipe pile components through quasi-static, dynamic compression and splitting tensile tests and… More >

Yangao Hu^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.3, pp. 1-1, 2023, DOI:10.32604/icces.2023.09773

Abstract This paper investigates the effects of graphene oxide (GO), notch depth, rebar, and load on the resistivity of cement paste and mortar. The electrical conductivity of GO/cement composite reaches its maximum value when the GO content is 0.03%, which is approximately 50% higher compared to the composite without GO. The resistivity of GO/cement composite shows significant changes with increasing load from 0 to 40 kN. The gauge factor for compressive loading varies from about 26 to 73 for different GO contents. Moreover, the resistivity variation with the notch depth in GO/cement is found to be much greater than that in… More >

Tianyu Zhou¹, Liang Hao¹, Xin Xu^2,3, Meng Si^2,3, Lian Zhang^2,3,*

Energy Engineering, Vol.121, No.1, pp. 145-168, 2024, DOI:10.32604/ee.2023.042798

Abstract This paper discussed the experimental results of the performance of an organic Rankine cycle (ORC) system with an ultra-low temperature heat source. The low boiling point working medium R134a was adopted in the system. The simulated heat source temperature (SHST) in this work was set from 39.51°C to 48.60°C by the simulated heat source module. The influence of load percentage of simulated heat source (LPSHS) between 50% and 70%, the rotary valve opening (RVO) between 20% and 100%, the resistive load between 36 Ω and 180 Ω or the no-load of the generator, as well as the autumn and winter… More >