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  • Open Access

    ARTICLE

    Effect of Patent Ductus Arteriosus on Pulmonary Vascular Disease

    Ranjit Philip1, Jason Nathaniel Johnson1,2, Ronak Naik1, Dai Kimura1,3, Umar Boston1, Sandeep Chilakala1, Benjamin Hendrickson1, Benjamin Rush Waller1, Shyam Sathanandam1

    Congenital Heart Disease, Vol.14, No.1, pp. 37-41, 2019, DOI:10.1111/chd.12702

    Abstract The hemodynamic effects of a patent ductus arteriosus (PDA) are well known including systemic hypoperfusion and volume overload on the left ventricle. This article aims to provide a review of the long-standing effect of a hemodynamically significant PDA on the pulmonary vasculature and the role of cardiac catheterization in preterm infants with a PDA and pulmonary hypertension. More >

  • Open Access

    ARTICLE

    Effect of patent ductus arteriosus on the heart in preterm infants

    Ranjit Philip1, Jeffrey A. Towbin1, Shyam Sathanandam 1, Jason Goldberg1, Thomas Yohannan1, Nithya Swaminathan1, Jason Nathaniel Johnson1,2

    Congenital Heart Disease, Vol.14, No.1, pp. 33-36, 2019, DOI:10.1111/chd.12701

    Abstract There continues to be controversy on the long‐term effects of a patent ductus arte‐ riosus (PDA) and its management. However, the hemodynamic effects of a large PDA in a preterm infant are well known. This article aims to provide insight into the adap‐ tive changes and remodeling effects of a PDA on the myocardium in preterm infants. More >

  • Open Access

    ARTICLE

    Kinematic Analysis and Rock Mass Classifications for Rock Slope Failure at USAID Highways

    Ibnu Rusydy1,3,*, Nafisah Al-Huda1,2, M. Fahmi4, Naufal Effendi4

    Structural Durability & Health Monitoring, Vol.13, No.4, pp. 379-398, 2019, DOI:10.32604/sdhm.2019.08192

    Abstract Rock slope kinematic analysis and rock mass classifications has been conducted at the 17th km to 26th km of USAID (United States Agency for International Development) highway in Indonesia. This research aimed to examine the type of rock slope failures and the quality of rock mass as well. The scan-line method was performed in six slopes by using a geological compass to determine rock mass structure on the rock slope, and the condition of joints such as persistence, aperture, roughness, infilling material, weathering and groundwater conditions. Slope kinematic analysis was performed employing a stereographic projection. The… More >

  • Open Access

    ABSTRACT

    Role of Myocardial Contractions on Coronary Vasoactivity

    Xiao Lu1,*, Ghassan Kassab1

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 84-86, 2019, DOI:10.32604/mcb.2019.07089

    Abstract This article has no abstract. More >

  • Open Access

    ABSTRACT

    Computational Biomechanical Right Ventricle Modeling with Contracting Bands to Improve Ventricle Cardiac Function for Patient with Repaired Tetralogy of Fallot

    Han Yu1, Tal Geva2, Rahul H. Rathod2, Alexander Tang2, Chun Yang3, Zheyang Wu3, Kristen L. Billiar4, Xueying Huang5, Dalin Tang1,*,3

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 56-57, 2019, DOI:10.32604/mcb.2019.07257

    Abstract Computational biomechanical models are widely used in cardiovascular research for better understanding of mechanisms governing disease development, quantitative diagnostic strategies and improved surgical designs with better outcome. Patients with repaired tetralogy of Fallot (TOF) account for the majority of cases with late onset right ventricle (RV) failure. The current surgical approach, which includes pulmonary valve replacement/insertion (PVR), has yielded mixed results. An innovative PVR surgical approach was proposed using active contracting bands to help ventricle to contract and improve RV function measured by ejection fraction [1]. Muscle active contraction caused by sarcomere shortening leads to… More >

  • Open Access

    ABSTRACT

    Autodigestion in Physiological Shock, Organ Dysfunction and Death

    Erik B. Kistler1, Geert W. Schmid-Schönbein2,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 8-8, 2019, DOI:10.32604/mcb.2019.07256

    Abstract A longstanding question in research on organ failure after physiological shock (such as trauma, burns, sepsis, surgery and medical emergencies) is the underlying mechanism for a progressive loss of cell and tissue functions. Our systematic analysis of this problem has served to identify digestive enzymes as key players [1, 2]. After synthesis and discharge from the pancreas, the digestive enzymes are usually contained inside the lumen of the small intestine where they break down food every day. Escape of the digestive enzymes out of the lumen of the intestine is kept to a minimum by… More >

  • Open Access

    ABSTRACT

    A Failure-Predicting Intelligent PYTHON (IP) Code for Monitoring A Crack of Irregular Shape in A Pipe#

    Jeffrey T. Fong1,*, Pedro V. Marcal2, Robert Rainsberger3, N. A. Heckert1, J. J. Filliben1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.21, No.2, pp. 45-45, 2019, DOI:10.32604/icces.2019.05432

    Abstract When a small crack is detected in a pressure vessel or piping, we can estimate the fatigue life of the vessel or piping by applying the classical law of fracture mechanics for crack growth if we are certain that the crack growth exponent is correct and the crack geometry is a simple plane. Unfortunately, for an ageing vessel or piping, the degradation will change the crack growth exponent, and the crack will advance not in a simple planar fashion. To validate the crack growth exponent for an ageing vessel or piping with a crack of… More >

  • Open Access

    ARTICLE

    Evaluation of Mechanical Properties of Cross-Laminated Timber with Different Lay-ups Using Japanese Larch

    Yingchun Gong1,#,*, Fenglu Liu2,#, Zhaopeng Tian1, Guofang Wu1, Haiqing Ren1, Cheng Guan2

    Journal of Renewable Materials, Vol.7, No.10, pp. 941-956, 2019, DOI:10.32604/jrm.2019.07354

    Abstract Japanese larch is one of the main plantation tree species in China. A lack of engineered wood products made by Japanese larch , limits its application in wood structures. In this study, based on optimum process para meters, such as pressure (1.2 MPa), adhesive spread rate (200 g/m 2 ) and adhesive (one component polyurethane), the mechanical properties of Japanese larch made cross laminated timber ( with different lay ups were evaluated by means of the static method . Results of this study show ed that variations in lay ups significant ly affected the mechanical… More >

  • Open Access

    ARTICLE

    Evaluation of the Out-of-Plane Shear Properties of Cross-Laminated Timber

    Yin Yang1, Xiaoyan Cao1, Zhiqiang Wang1,*, Zhijun Liang1, Jianhui Zhou2,*

    Journal of Renewable Materials, Vol.7, No.10, pp. 957-965, 2019, DOI:10.32604/jrm.2019.07558

    Abstract The out-of-plane shear properties of cross-laminated timber (CLT) substantially influence the overall mechanical properties of CLT. Various testing methods and theories related to these properties have recently been developed. The effects of the number of layers (three and five layers) and testing method (short-span three- and four-point bending tests) on the out-of-plane shear properties of CLT were evaluated. The out-of-plane shear strength values were calculated based on different theories for comparison. The failure mode in the short-span four-point bending (FPB) method was mainly the rolling shear (RS) failure in the cross layers, indicating that the More >

  • Open Access

    ABSTRACT

    Modelling of Progressive Failures in Quasi-Brittle Media Via a Temporal Stress-Redistribution Mechanism

    Jinxing Liu

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.21, No.1, pp. 8-8, 2019, DOI:10.32604/icces.2019.04952

    Abstract A new method is proposed to simulate progressive failure processes in heterogeneous brittle materials such as concrete, ceramics, rocks etc., by considering the time-dependence of stress redistributions induced by local breakages. Two mechanisms of stress redistribution are incorporated into the proposed model in order to account for the influence of each local breakage on the remaining specimen: (1) One is the immediate release of internal forces in the breaking element, which is assumed to happen within an infinitesimal time when compared with the characteristic time of external loadings. The release of such internal forces is… More >

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