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  • Open Access

    REVIEW

    Adjuvant radiation treatment after prostatectomy. Where do we stand?

    Mohamed A. Elshaikh1, Dina R. Ibrahim1, Hans Stricker2, James O. Peabody2

    Canadian Journal of Urology, Vol.18, No.2, pp. 5592-5600, 2011

    Abstract Introduction: Prostate cancer is the second most common cause of cancer death in American men. For patients with adverse pathologic features, postoperative radiotherapy to prostate bed after radical prostatectomy has been shown in randomized studies to improve many important clinical endpoints including overall survival. In this review article, we distinguish adjuvant radiation treatment (ART) from salvage radiation treatment (SRT), discuss the evidences for ART and its potential side effects focusing on the debate concerning the optimal timing of post prostatectomy radiation treatment (RT).
    Material and methods: A comprehensive literature search was conducted in MEDLINE including pre-MEDLINE.
    Conclusion: For More >

  • Open Access

    RESIDENT’S CORNER

    Bilateral renal malakoplakia with acute renal failure: a case report and literature review

    Lee A. Richter1,2, Michael Isaacson1,2, Mohan Verghese2, Jayashree Krishnan3

    Canadian Journal of Urology, Vol.18, No.5, pp. 5911-5913, 2011

    Abstract Malakoplakia involving the genitourinary tract is a rare infl ammatory disorder that presents a diagnostic challenge. Renal parenchymal involvement is particularly uncommon. We report a case of bilateral renal malakoplakia that presented with acute renal failure and simulated xanthogranulomatous pyelonephritis (XGP). The etiology, clinical course, and management of malakoplakia are reviewed, emphasizing the distinct characteristics of the disease that lead to its accurate diagnosis. More >

  • Open Access

    RESIDENT’S CORNER

    Hypercreatinemia: think beyond acute kidney injury

    Ankur Gupta1, Mohan Biyani1, Mudit Gupta2, Marc Eric Saltel3

    Canadian Journal of Urology, Vol.18, No.6, pp. 6066-6068, 2011

    Abstract Urinary bladder rupture associated with severe hypercreatinemia is a rare clinical presentation. We herein report a 60-year-old interesting patient who was found to have intraperitoneal bladder rupture and pseudo-renal failure. High rate of suspicion and timely diagnosis is the key in management of this condition, which led to complete recovery in our patient. More >

  • Open Access

    ABSTRACT

    A three dimensional efficient Galerkin mshfree formulation for large deformation analysis of soil slope failure

    Dongdong Wang, Zhuoya Li, Youcai Wu

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.17, No.4, pp. 107-108, 2011, DOI:10.3970/icces.2011.017.107

    Abstract Meshfree methods have experienced substantially fundamental development and various applications. One distinguished advantage for meshfree methods is that they can relieve the mesh tangling burden of FEM and are more suitable for finite deformation analysis. In this work a three dimensional updated Lagrangian Galerkin meshfree formulation with improved computational efficiency is presented to analyze the failure of soil slopes. This nonlinear meshfree formulation is featured by the Lagrangian stabilized conforming nodal integration method where the low cost nature of nodal integration approach is kept and at the same time the numerical stability is obtained as… More >

  • Open Access

    ABSTRACT

    Improved material point method for simulating the zona failure response in piezo-assisted intracytoplasmic sperm injection

    Y. Gan, Z. Chen, S. Montgomery-Smith

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.18, No.2, pp. 59-60, 2011, DOI:10.3970/icces.2011.018.059

    Abstract The material point method (MPM), which is an extension from computational fluid dynamics (CFD) to computational solid dynamics (CSD), is improved for the coupled CFD and CSD simulation of the zona failure response in piezo-assisted intracytoplasmic sperm injection (piezo-ICSI). To evaluate the stresses at any zona material point, a plane stress assumption is made in the local tangent plane of the membrane point, and a simple procedure is proposed to find the effective point connectivity for the orientation of the local tangent plane. With an iterative algorithm in each time step, the original MPM is More >

  • Open Access

    ABSTRACT

    A Case Study of Mud-Weight Design with Finite Element Method for Subsalt Wells

    X.P. Shen, A. Diaz, T. Sheehy ,

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.16, No.3, pp. 73-74, 2011, DOI:10.3970/icces.2011.016.073

    Abstract This paper presents a case study for the design of a mud-weight window (MWW) with three-dimensional (3D) finite-element (FE) tools for subsalt wells. The trajectory of the target well penetrates a 20,000-ft thick salt body.

    The numerical solution of the MWW for the target wellbore consists two parts: the shear failure gradient (SFG) and the fracture gradient (FG). Because the pore pressure and material distributions are nonuniform, the calculations of SFG and FG must be performed with submodeling techniques for a given depth point at a smaller local scale. A numerical scheme has been proposed… More >

  • Open Access

    ARTICLE

    Elasto-Plastic Analysis of Structural Problems Using Atomic Basis Functions

    V. Kozulić1, B. Gotovac1

    CMES-Computer Modeling in Engineering & Sciences, Vol.80, No.3&4, pp. 251-274, 2011, DOI:10.3970/cmes.2011.080.251

    Abstract The numerical model for the elasto-plastic analysis of prismatic bars subjected to torsion is developed. The functions implemented in this model are Fup basis functions which belong to the class of atomic functions. The collocation method is used to form a system of equations in which the differential equation of the problem is satisfied in collocation points of closed domain, while boundary conditions are satisfied exactly at the domain boundary. The propagation of plastic zones in the cross-section is monitored by applying the incremental-iterative procedure until failure. An approximate solution of arbitrary accuracy is attained More >

  • Open Access

    ARTICLE

    Improved Material Point Method for Simulating the Zona Failure Response in Piezo-Assisted Intracytoplasmic Sperm Injection

    Y. Gan1, Z. Chen2,3, S. Montgomery-Smith4

    CMES-Computer Modeling in Engineering & Sciences, Vol.73, No.1, pp. 45-76, 2011, DOI:10.3970/cmes.2011.073.045

    Abstract The material point method (MPM), which is an extension from computational fluid dynamics (CFD) to computational solid dynamics (CSD), is improved for the coupled CFD and CSD simulation of the zona failure response in piezo-assisted intracytoplasmic sperm injection (piezo-ICSI). To evaluate the stresses at any zona material point, a plane stress assumption is made in the local tangent plane of the membrane point, and a simple procedure is proposed to find the effective point connectivity for the orientation of the local tangent plane. With an iterative algorithm in each time step, the original MPM is More >

  • Open Access

    ARTICLE

    Recent Developments on Thermo-Mechanical Simulations of Ductile Failure by Meshfree Method

    B. Ren1,2, J. Qian1, X. Zeng1, A. K. Jha3, S. Xiao4, S. Li1,5

    CMES-Computer Modeling in Engineering & Sciences, Vol.71, No.3, pp. 253-278, 2011, DOI:10.3970/cmes.2011.071.253

    Abstract Ductile failure is a complex multi-scale phenomenon evolved from the micro-voids to macro-crack. There are three main failure mechanisms behinds a ductile failure: adiabatic shear band (ASB), spall fracture, and crack. Since this type of thermo-mechanical phenomena involves large deformation and large scale plastic yielding, a meshfree method has intrinsic advantages in solving this kind of problems over the conventional finite element method. In this paper, the numerical methodologies including multi-physics approach for ASB, parametric visibility condition for crack propagation, and multi-scale approach to determine spall strength in simulating ductile failure have been reviewed. A More >

  • Open Access

    ARTICLE

    Dynamic Failure Behavior of Nanocrystalline Cu at Atomic Scales

    A. M. Dongare1,2, A. M. Rajendran3, B. LaMattina4, M. A. Zikry1, D. W. Brenner1

    CMC-Computers, Materials & Continua, Vol.24, No.1, pp. 43-60, 2011, DOI:10.3970/cmc.2011.024.043

    Abstract Large-scale molecular dynamics (MD) simulations are used to investigate the effects of microstructure and loading conditions on the dynamic failure behavior of nanocrystalline Cu. The nucleation, growth, and coalescence of voids is investigated for the nanocrystalline metal with average grain sizes ranging from 6 nm to 12 nm (inverse Hall-Petch regime) for conditions of uniaxial expansion at constant strain rates ranging from 4x107 s - 1 to 1010 s - 1. MD simulations suggest that the evolution of voids can be described in two stages: The first stage corresponds to the nucleation of voids and… More >

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