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  • Open Access

    ARTICLE

    Exploration of the oxidative-inflammatory potential targets of Coicis Semen in osteoarthritis: Data mining and systematic pharmacology

    QIAO ZHOU2,3,4, JIAN LIU1,2,*, LING XIN1, YANYAN FANG1,2, LEI WAN1,2, DAN HUANG1,2, JIANTING WEN1,2

    BIOCELL, Vol.47, No.7, pp. 1623-1643, 2023, DOI:10.32604/biocell.2023.028331 - 21 June 2023

    Abstract Objective: On the basis of data mining, systematic pharmacology, molecular docking, and experiment validation, the oxidative-inflammatory molecular targets of Coicis Semen in the therapy of osteoarthritis (OA) were explored. Methods: The association rule analysis was effectively applied to highlight the correlation between Coicis Semen and oxidative inflammation indices. The random walk model was subsequently used to evaluate the clinical efficacy of Coicis Semen. Network pharmacology was used to predict network targets. The binding affinity of the active ingredient in Coicis Semen to the key target of OA was also successfully predicted. Results: Coicis Semen showed a significant reduction in oxidative-inflammatory indicators… More >

  • Open Access

    ARTICLE

    Pollination Biology of the Endangered Herbal Medicines Dendrobium chrysotoxum (Orchidaceae)

    Kai Luo1, Yanbing Bai1, Yan Jiang1, Guiling Li1, Min Jia1, Yongguo He1, Zhijun Yao1, Ziwei Xiao1, Xiaoqiong Liu1, Wenjie Liu2, Shanshan Yin1,*, Zesheng Li1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.7, pp. 1975-1986, 2023, DOI:10.32604/phyton.2023.028232 - 29 May 2023

    Abstract Pollination biology studies of the endangered herbal medicines Dendrobium chrysotoxum were conducted in natural pollination conditions using flower observation, pollinator observation and artificial pollination experiments. Populations of D. chrysotoxum with fragrance and nectar were pollinated by Ctenoplectra davidi Valhalla (Hymenoptera: Apidae) species. The floral structure of D. chrysotoxum adapted precisely to its pollinators. Flowers had a low capsule setting (0.17%) under natural conditions. However, compared to open pollination, artificial pollination experiments showed a significant increase in capsule setting, and D. chrysotoxum was cross-compatible and self-compatible, but there was pollinator limitation also. This study will provide important information for the preservation More >

  • Open Access

    ARTICLE

    Evaluation of Pre-Emergence and Post-Emergence Herbicides for Weed Management in Miscanthus sacchariflorus and Miscanthus sinensis

    Bimal Kumar Ghimire1, Chang Yeon Yu2, Seung Hyun Kim1, Ill Min Chung1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.5, pp. 1439-1467, 2023, DOI:10.32604/phyton.2023.023076 - 09 March 2023

    Abstract Miscanthus, is a promising bioenergy crop, considered superior to other bioenergy crops because of its higher water and nutrient use efficiency, cold tolerance, and higher production of biomass. Broadleaf weeds and grass weeds, cause major problems in the Miscanthus field. A field experiment was conducted in 2018 and 2019, to assess the effects of pre-emergence (alachlor and napropamide) and post-emergence herbicides (nicosulfuron, dicamba, bentazon, and glufosinate ammonium) on broadleaf and grass weeds in M. sinensis and M. sacchariflorus fields. The weed control efficiency and phytotoxicity of pre- and post-emergence herbicides were evaluated at 30 days after treatment (DAT) and… More >

  • Open Access

    REVIEW

    Indian medicinal plants are effective in the treatment and management of COVID-19

    SUBHASH CHANDRA1,2, SANTWANA PALAI3, EDINARDO FAGNER FERREIRA-MATIAS4, IVO CAVALCANTE PITA-NETO4, CíCERO LUCAS GOMES-RAMALHO4, EDLANE MARTINS DE ANDRADE4, RAY SILVA DE ALMEIDA5, MARCELLO IRITI6,7,*, HENRIQUE DOUGLAS MELO-COUTINHO5,*

    BIOCELL, Vol.47, No.4, pp. 677-695, 2023, DOI:10.32604/biocell.2023.026081 - 08 March 2023

    Abstract Indian medicinal plants are referred to as the “nectar of life” owing to their phytochemicals and bioactive complexes that are beneficial in treating diseases. Coronavirus disease 2019 (COVID-19) is a global health issue without any proper medication. The indigenous plants of India can be exploited to control the precise signs of SARS-CoV-2. The Ministry of AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) has advised routine usage of medicinal plants for COVID-19. Medicinal plants like Zingiber officinalis, Azadirachta indica, Ocimum sanctum, Nigella sativa, Withania somnifera, Curcuma longa, Piper nigrum, Allium sativum, Tinospora cordifolia, etc. have More >

  • Open Access

    ARTICLE

    Selection of Stable Reference Genes for Quantitative Real-Time PCR on Herbaceous Peony (Paeonia lactiflora Pall.) in Response to Drought Stress

    Zhipeng Sheng, Yuting Luan, Cong Xu, Jun Tao*, Daqiu Zhao*

    Phyton-International Journal of Experimental Botany, Vol.92, No.3, pp. 801-814, 2023, DOI:10.32604/phyton.2023.024953 - 29 November 2022

    Abstract Herbaceous peony (Paeonia lactiflora Pall.), as a high-end cut flower in the international market, has high ornamental and medicinal values. But in Northern China, drought is a major environmental factor influencing the growth and development of P. lactiflora. Quantitative real-time polymerase chain reaction (qRT-PCR) can evaluate gene expression levels under different stress conditions, and stable internal reference is the key for qRT-PCR. At present, there is no systematic screening of internal reference for correcting gene expressions of P. lactiflora in response to drought stress. In this study, 10 candidate genes [ubiquitin (UBQ2), UBQ1, elongation factor 1-α (EF-1α), Histidine (His), eukaryotic… More >

  • Open Access

    ARTICLE

    Structure and Properties of PLA Composite Enhanced with Biomass Fillers from Herbaceous Plants

    Haining Na1,*, Juncheng Huang1, Hongguang Xu2, Fei Liu3, Liangke Xie1, Baoqing Zhu3, Jiuchen Wang2, Jin Zhu1,*

    Journal of Renewable Materials, Vol.11, No.2, pp. 491-503, 2023, DOI:10.32604/jrm.2023.024181 - 22 September 2022

    Abstract PLA composites containing biomass fillers from the three herbaceous plants such as reed, wheat stalk, and coconut fiber with length and diameter at the scale of several millimeters were prepared without using additives. The reinforcement effect on the properties of PLA/biomass filler composites is investigated. The research results show that the PLA/biomass filler composites exhibit good stiffness, flexural strength, and impact toughness. Among the three kinds of biomass fillers, reed reinforced PLA composites show optimal mechanical properties. When filled with 40%–50% reed, the flexural moduli of the composites are over 7000 MPa. Flexural strength retains More > Graphic Abstract

    Structure and Properties of PLA Composite Enhanced with Biomass Fillers from Herbaceous Plants

  • Open Access

    REVIEW

    SOLAR DRYING OF HERBAL WEALTH IN EASTERN HIMALAYA: A REVIEW

    Priyanka Chauhana , Himani Pathaniaa, Shriyaa, Neetikaa, Nidhia, Sakshia, Sheetal Choudharya, Rajesh Kumarb,*, Mamta Sharmaa,c,*, Sameer Rahatekard, Anil Kumare,*

    Frontiers in Heat and Mass Transfer, Vol.18, pp. 1-20, 2022, DOI:10.5098/hmt.18.34

    Abstract Solar dryers have proven to be one of the best environmentally friendly approaches for drying purpose of medicinal plants and agricultural crops. Use of solar radiations in drying purpose of plant parts has proven economically as well as environmentally responsible and sensible application. Plants are the treasure of nature with hidden medicinal properties to treat diseases. Plant material should be processed properly for extraction of medicinal molecules in terms drying to decrease the manufacturing loss and to increase the standard of product. Cognizances of ethnobotanical knowledge on plant wealth are extremely beneficial in utilization and… More >

  • Open Access

    ARTICLE

    Topical Application of Houttuynia cordata Thunb Ethanol Extracts Increases Tumor Infiltrating CD8+ /Treg Cells Ratio and Inhibits Cutaneous Squamous Cell Carcinoma in vivo

    Lipeng Gao1,2,#, Rongyin Gui1,#, Xinnan Zheng1, Yingxue Wang1, Yao Gong1, Tim Hua Wang1, Jichuang Wang3, Junyi Huang1,2, Xinhua Liao1,2,*

    Oncologie, Vol.24, No.3, pp. 565-577, 2022, DOI:10.32604/oncologie.2022.022454 - 19 September 2022

    Abstract Houttuynia cordata Thunb (HCT) is a medicinal and edible herb that has beneficial effects on various diseases due to its diuretic, anti-inflammatory, anti-oxidative, anti-microbial, anti-viral, anti-cancer and anti-diabetic properties. Most reports of its anti-cancer activity were conducted in vitro, and its effects on cutaneous squamous cell carcinoma (SCC) have not been investigated yet. Using DMBA/TPA induced SCC mice model, we found that topical treatment by HCT, as well as its bioactive ingredient monomer, efficiently inhibited tumor growth. Mechanistically, tumor infiltrating CD4+ , Foxp3+ T regulatory cells (Tregs) were significantly reduced and CD8+ /Treg cells ratio was largely increased More >

  • Open Access

    ARTICLE

    Chinese Herbal Prescription QYSL Prevents Progression of Lung Cancer by Targeting Tumor Microenvironment

    Yang Chen1,#, Huan Wu2,#, Annan Jiao3, Jiabing Tong4, Jie Zhu5, Mei Zhang1, Zegeng Li4,*, Ping Li1,*

    Oncologie, Vol.24, No.2, pp. 295-307, 2022, DOI:10.32604/oncologie.2022.022116 - 29 June 2022

    Abstract Objectives: Lung cancer is a common and malignant tumor in adults and ranks first in the incidence and mortality of the top five malignant tumors in China. Our previous studies have shown that QYSL prescription can balance lung cancer mice Th1/Th2 and inhibit tumor cell immune escape. Here, we examined the effects of QYSL on lung cancer associated macrophage and the potential associated mechanism. Methods: C57BL/6 mice were injected with Lewis lung cancer cells and treated with QYSL. FACS, RT-PCR, and western blot were used to examined the effect of QYSL on tumor immune microenvironment. Results: We… More >

  • Open Access

    ARTICLE

    Age-Related Alterations in DNA Methylation and APETALA2 (AP2) Levels in Herbaceous Peony (Paeonia lactiflora Pall.)

    Yanqing Wu1,2, Jiao Liu1, Yuhan Tang2, Daqiu Zhao2, Jun Tao1,2,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.9, pp. 2005-2016, 2022, DOI:10.32604/phyton.2022.021062 - 13 May 2022

    Abstract The ornamental and commercial values of herbaceous peony (Paeonia lactiflora Pall.) are directly related to its flower pattern. However, the molecular mechanisms underlying the type formation of P. lactiflora flowers have not been studied in great detail. Previous studies identified, using integrated multipleomics analysis, revealed that APETALA2 (AP2) is an important candidate gene that modulates type formation of P. lactiflora flowers. To further reveal the expression mechanism of AP2 in P. lactiflora petals, we examined the profile of AP2 expression in the inner and outer petals of ‘ZiFengyu’ at various developmental stages using qRT-PCR and BSP+Miseq methylation analysis. Based on our data,… More >

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