Hoi Lam She^*, Arno A.W. Roest^†, Emmeline E. Calkoen^†, Pieter J. van den Boogaard^‡, Rob J. van der Geest^‡, Mark G. Hazekamp^§, Albert de Roos^‡, Jos J.M. Westenberg^‡

Congenital Heart Disease, Vol.12, No.1, pp. 40-48, 2017

Abstract Purpose. To evaluate the inflow pattern and flow quantification in patients with functional univentricular heart after Fontan’s operation using 4D flow magnetic resonance imaging (MRI) with streamline visualization when compared with the conventional 2D flow approach.
Method. Seven patients with functional univentricular heart after Fontan’s operation and twenty-three healthy controls underwent 4D flow MRI. In two orthogonal two-chamber planes, streamline visualization was applied, and inflow angles with peak inflow velocity (PIV) were measured. Transatrioventricular flow quantification was assessed using conventional 2D multiplanar reformation (MPR) and 4D MPR tracking the annulus and perpendicular to the streamline inflow at… More >

Muhannad Alsyouf, Mohamed Keheila, Michelle Marinone, Allie Blackburn, Andrea Staack

Canadian Journal of Urology, Vol.23, No.1, pp. 8168-8170, 2016

Abstract Patients undergoing InterStim implantation often have comorbidities, which require magnetic resonance imaging (MRI) for diagnosis. Although MRI of the head has been recently approved for use with the InterStim neurostimulator, imaging of other regions remains controversial. We present a case of Achilles tendinitis diagnosed on MRI of the ankle in a patient with an InterStim device. The neurostimulator was deactivated, and using a transmit/receive extremity coil, the left ankle was imaged without any adverse events. At 9 months post-imaging, the patient continued to have good control of symptoms with InterStim, with no negative effects from More >

Chunliu He¹, Jiaqiu Wang², Yuxiang Huang¹, Tongjing Zhu¹, Yuehong Miao¹, Zhiyong Li^1,2*

Molecular & Cellular Biomechanics, Vol.13, No.1, pp. 23-36, 2016, DOI:10.3970/mcb.2016.013.027

Abstract Fibrous cap thickness (FCT) is seen as critical to plaque vulnerability. Therefore, the development of automatic algorithms for the quantification of FCT is for estimating cardiovascular risk of patients. Intravascular optical coherence tomography (IVOCT) is currently the only in vivo imaging modality with which FCT, the critical component of plaque vulnerability, can be assessed accurately. This study was aimed to discussion the correlation between the texture features of OCT images and the FCT in lipid-rich atheroma. Methods: Firstly, a full automatic segmentation algorithm based on unsupervised fuzzy c means (FCM) clustering with geometric constrains was… More >

Gregory J. Diorio¹, Daniel J. Canter^2,3

Canadian Journal of Urology, Vol.22, No.2, pp. 7763-7766, 2015

Abstract For patients with non-muscle invasive bladder cancer, cystoscopy and transurethral resection/vaporization of the bladder tumor plays an integral role in the treatment of a given patient’s bladder cancer. Although considered the current gold standard for tumor detection, traditional or white light cystoscopy has been shown to have its limitations visualizing both small papillary tumors and/or carcinoma in-situ. Current efforts have been directed to closing this gap with data demonstrating that by identifying these previously missed lesions, tumor recurrence and progression rates are reduced, thereby improving patient outcomes.
Narrow Band Imaging, which can be used during… More >

Ali-Reza Sharif-Afshar¹, Tom Feng¹, Steven Koopman¹, Christopher Nguyen², Quanlin Li³, Eugene Shkolyar¹, Rola Saouaf², Hyung L. Kim¹

Canadian Journal of Urology, Vol.22, No.2, pp. 7698-7702, 2015

Abstract Introduction: Hemorrhage induced by prostate biopsy can interfere with the interpretation of prostate magnetic resonance imaging (MRI).
Materials and methods: We reviewed 101 patients who had prostate multiparametric MRI (MP-MRI) and radical prostatectomy.
Results: On MRI obtained within 4 weeks following the biopsy, hemorrhage was seen in 26/36 (72.2%) patients. Patients having a MRI between 4-6 weeks of the biopsy had hemorrhage in 8/14 (57.1%) cases. After 6 weeks, hemorrhage was less common but still present in 24/46 (52%) patients. There were five patients who had prostate MRI prior to biopsy and served as a control… More >

Seyed Saeid Dianat¹, H. Ballentine Carter^2,4, Edward M. Schaeffer^2,4, Ulrike M. Hamper^1,2, Jonathan I. Epstein^2,3,4, Katarzyna J. Macura^1,2,4

Canadian Journal of Urology, Vol.22, No.5, pp. 7965-7972, 2015

Abstract Introduction: Purpose of this pilot study was to correlate quantitative parameters derived from the multiparametric magnetic resonance imaging (MP-MRI) of the prostate with results from MRI guided transrectal ultrasound (MRI/TRUS) fusion prostate biopsy in men with suspected prostate cancer.
Materials and methods: Thirty-nine consecutive patients who had 3.0T MP-MRI and subsequent MRI/TRUS fusion prostate biopsy were included and 73 MRI-identified targets were sampled by 177 cores. The pre-biopsy MP-MRI consisted of T2-weighted, diffusion weighted (DWI), and dynamic contrast enhanced (DCE) images. The association of quantitative MRI measurements with biopsy histopathology findings was assessed by Mann-Whitney U-test and… More >

David Leung, Saravanan Krishnamoorthy, Lawrence Schwartz, Chaitanya Divgi

Canadian Journal of Urology, Vol.21, Suppl.2, pp. 42-47, 2014

Abstract instruction: Introduction: In conjunction with biomarkers, imaging is an important component of the diagnostic workup and subsequent management of men with prostate cancer.
instruction: Materials and methods: The relevant literature was retrieved from a search of MEDLINE with appropriate keywords.
instruction: Results: Osseous metastases develop in close to 90% of patients with metastatic prostate cancer, thus making bone scans (single photon, using Tc-99m labeled phosphonates) the mainstay of imaging in advanced prostate cancer. Bone scans are limited by their lack of specificity and an unclear relationship between bone scan changes and disease progression or response to therapy. In… More >

Leonard G. Gomella¹, Daniel P. Petrylak², Bobby Shayegan³

Canadian Journal of Urology, Vol.21, Suppl.2, pp. 1-6, 2014

Abstract instruction: Introduction: Newer approaches to the management of advanced prostate cancer have rapidly evolved. While basic androgen deprivation remains as the first line in newly diagnosed hormone naïve metastatic prostate cancer, the agents used and strategies followed have undergone significant changes. Numerous new agents such as sipuleucel-T, abiraterone, enzalutamide, cabazitaxel and radium-223 have all been approved since 2010 to treat metastatic castration-resistant prostate cancer (CRPC). New imaging techniques to detect advanced disease such as F-18 PET, 11C-choline PET and other modalities are becoming available. The concepts of "bone health" and the management of side effects related… More >

Brian J. Linder¹, Akira Kawashima², David A. Woodrum², Matthew K. Tollefson¹, R. Jeffrey Karnes¹, Brian J. Davis³, Laureano J. Rangel⁴, Bernard F. King², Lance A. Mynderse¹

Canadian Journal of Urology, Vol.21, No.3, pp. 7283-7289, 2014

Abstract Introduction: To evaluate the ability of endorectal coil (e-coil) magnetic resonance imaging (MRI) to identify early prostatic fossa recurrence after radical prostatectomy.
Materials and methods: We identified 187 patients from 2005–2011 who underwent e-coil MRI with dynamic gadolinium-contrast enhancement followed by transrectal ultrasound (TRUS) guided prostatic fossa biopsy for possible local prostate cancer recurrence. For analysis, local recurrence was defined as a negative evaluation for distant metastatic disease with a positive prostatic fossa biopsy, decreased prostate-specific antigen (PSA) following salvage radiation therapy, or increased lesion size on serial imaging.
Results: Local recurrence was identified in 132 patients, with… More >

Daniel A. Wollin¹, Fang-Ming Deng², William C. Huang¹, James S. Babb³, Andrew B. Rosenkrantz³

Canadian Journal of Urology, Vol.21, No.5, pp. 7454-7459, 2014

Abstract Introduction: To compare qualitative and quantitative imaging features from conventional and diffusion-weighted (DW) magnetic resonance imaging (MRI) in detection of metastatic pelvic lymph nodes in bladder cancer patients undergoing cystectomy.
Materials and methods: Thirty-six patients who had undergone cystectomy for bladder cancer with preoperative MRI with DWI sequence prior to surgery were included. Imaging features on conventional and DW-MRI were compared with histopathology at cystectomy.
Results: Nodal features associated with metastatic lymphadenopathy were short axis (AUC = 0.85, p < 0.001; when SA > 5 mm: sensitivity = 88%, specificity = 75%), long axis (AUC =… More >