Zhenhui Cai, Kaiqing Zhou^*, Zhouhua Liao

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 2255-2303, 2025, DOI:10.32604/cmc.2025.067994 - 23 September 2025

Abstract The YOLO (You Only Look Once) series, a leading single-stage object detection framework, has gained significant prominence in medical-image analysis due to its real-time efficiency and robust performance. Recent iterations of YOLO have further enhanced its accuracy and reliability in critical clinical tasks such as tumor detection, lesion segmentation, and microscopic image analysis, thereby accelerating the development of clinical decision support systems. This paper systematically reviews advances in YOLO-based medical object detection from 2018 to 2024. It compares YOLO’s performance with other models (e.g., Faster R-CNN, RetinaNet) in medical contexts, summarizes standard evaluation metrics (e.g.,… More >

Hazem Farah¹, Akram Bennour^1,*, Hama Soltani¹, Mouaaz Nahas², Rashiq Rafiq Marie³, Mohammed Al-Sarem^3,4,*

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3335-3348, 2025, DOI:10.32604/cmc.2025.067226 - 23 September 2025

Abstract This study presents an advanced method for post-mortem person identification using the segmentation of skeletal structures from chest X-ray images. The proposed approach employs the Attention U-Net architecture, enhanced with gated attention mechanisms, to refine segmentation by emphasizing spatially relevant anatomical features while suppressing irrelevant details. By isolating skeletal structures which remain stable over time compared to soft tissues, this method leverages bones as reliable biometric markers for identity verification. The model integrates custom-designed encoder and decoder blocks with attention gates, achieving high segmentation precision. To evaluate the impact of architectural choices, we conducted an… More >

Omar Sabri¹, Bassam Al-Shargabi^2,*, Abdelrahman Abuarqoub²

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 2443-2486, 2025, DOI:10.32604/cmc.2025.066987 - 23 September 2025

Abstract This review comprehensively analyzes advancements in artificial intelligence, particularly machine learning and deep learning, in medical imaging, focusing on their transformative role in enhancing diagnostic accuracy. Our in-depth analysis of 138 selected studies reveals that artificial intelligence (AI) algorithms frequently achieve diagnostic performance comparable to, and often surpassing, that of human experts, excelling in complex pattern recognition. Key findings include earlier detection of conditions like skin cancer and diabetic retinopathy, alongside radiologist-level performance for pneumonia detection on chest X-rays. These technologies profoundly transform imaging by significantly improving processes in classification, segmentation, and sequential analysis across… More >

Sunawar Khan¹, Tehseen Mazhar^1,2,*, Naila Sammar Naz¹, Fahad Ahmed¹, Tariq Shahzad³, Atif Ali⁴, Muhammad Adnan Khan^5,*, Habib Hamam^6,7,8,9

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 2347-2401, 2025, DOI:10.32604/cmc.2025.066932 - 23 September 2025

Abstract Feature selection (FS) plays a crucial role in medical imaging by reducing dimensionality, improving computational efficiency, and enhancing diagnostic accuracy. Traditional FS techniques, including filter, wrapper, and embedded methods, have been widely used but often struggle with high-dimensional and heterogeneous medical imaging data. Deep learning-based FS methods, particularly Convolutional Neural Networks (CNNs) and autoencoders, have demonstrated superior performance but lack interpretability. Hybrid approaches that combine classical and deep learning techniques have emerged as a promising solution, offering improved accuracy and explainability. Furthermore, integrating multi-modal imaging data (e.g., Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Positron… More >

Batyrkhan Omarov^1,2,3,4,*

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 2195-2253, 2025, DOI:10.32604/cmc.2025.064799 - 23 September 2025

Abstract Deep learning now underpins many state-of-the-art systems for biomedical image and signal processing, enabling automated lesion detection, physiological monitoring, and therapy planning with accuracy that rivals expert performance. This survey reviews the principal model families as convolutional, recurrent, generative, reinforcement, autoencoder, and transfer-learning approaches as emphasising how their architectural choices map to tasks such as segmentation, classification, reconstruction, and anomaly detection. A dedicated treatment of multimodal fusion networks shows how imaging features can be integrated with genomic profiles and clinical records to yield more robust, context-aware predictions. To support clinical adoption, we outline post-hoc explainability More >

Khalil Ibrahim Lairedj¹, Zouaoui Chama¹, Amina Bagdaoui¹, Samia Larguech², Younes Menni^3,4,*, Nidhal Becheikh⁵, Lioua Kolsi^6,*, Badr M. Alshammari⁷

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.2, pp. 2419-2443, 2025, DOI:10.32604/cmes.2025.069396 - 31 August 2025

Abstract Brain tumor segmentation from Magnetic Resonance Imaging (MRI) supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans, making it a crucial yet challenging task. Supervised models such as 3D U-Net perform well in this domain, but their accuracy significantly improves with appropriate preprocessing. This paper demonstrates the effectiveness of preprocessing in brain tumor segmentation by applying a pre-segmentation step based on the Generalized Gaussian Mixture Model (GGMM) to T1 contrast-enhanced MRI scans from the BraTS 2020 dataset. The Expectation-Maximization (EM) algorithm is employed to estimate parameters for four tissue classes, generating a More >

Majid Harouni^1,*, Vishakha Goyal¹, Gabrielle Feldman¹, Sam Michael², Ty C. Voss¹

CMC-Computers, Materials & Continua, Vol.85, No.1, pp. 331-366, 2025, DOI:10.32604/cmc.2025.067915 - 29 August 2025

Abstract Semantic segmentation plays a foundational role in biomedical image analysis, providing precise information about cellular, tissue, and organ structures in both biological and medical imaging modalities. Traditional approaches often fail in the face of challenges such as low contrast, morphological variability, and densely packed structures. Recent advancements in deep learning have transformed segmentation capabilities through the integration of fine-scale detail preservation, coarse-scale contextual modeling, and multi-scale feature fusion. This work provides a comprehensive analysis of state-of-the-art deep learning models, including U-Net variants, attention-based frameworks, and Transformer-integrated networks, highlighting innovations that improve accuracy, generalizability, and computational More >

Shaoyong Hong¹, Bo Yang², Yan Chen², Hao Quan³, Shan Liu⁴, Minyi Tang^5,*, Jiawei Tian^6,*

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.1, pp. 1091-1112, 2025, DOI:10.32604/cmes.2025.066165 - 31 July 2025

Abstract 3D medical image reconstruction has significantly enhanced diagnostic accuracy, yet the reliance on densely sampled projection data remains a major limitation in clinical practice. Sparse-angle X-ray imaging, though safer and faster, poses challenges for accurate volumetric reconstruction due to limited spatial information. This study proposes a 3D reconstruction neural network based on adaptive weight fusion (AdapFusionNet) to achieve high-quality 3D medical image reconstruction from sparse-angle X-ray images. To address the issue of spatial inconsistency in multi-angle image reconstruction, an innovative adaptive fusion module was designed to score initial reconstruction results during the inference stage and… More >

Rachana Poongodan¹, Dayanand Lal Narayan², Deepika Gadakatte Lokeshwarappa³, Hirald Dwaraka Praveena⁴, Dae-Ki Kang^5,*

CMC-Computers, Materials & Continua, Vol.84, No.3, pp. 5751-5772, 2025, DOI:10.32604/cmc.2025.066314 - 30 July 2025

Abstract In recent decades, brain tumors have emerged as a serious neurological disorder that often leads to death. Hence, Brain Tumor Segmentation (BTS) is significant to enable the visualization, classification, and delineation of tumor regions in Magnetic Resonance Imaging (MRI). However, BTS remains a challenging task because of noise, non-uniform object texture, diverse image content and clustered objects. To address these challenges, a novel model is implemented in this research. The key objective of this research is to improve segmentation accuracy and generalization in BTS by incorporating Switchable Normalization into Faster R-CNN, which effectively captures the… More >

Sameera V Mohd Sagheer^1,*, Meghana K H², P M Ameer³, Muneer Parayangat⁴, Mohamed Abbas⁴

CMC-Computers, Materials & Continua, Vol.84, No.3, pp. 4259-4297, 2025, DOI:10.32604/cmc.2025.063726 - 30 July 2025

Abstract Integrating multiple medical imaging techniques, including Magnetic Resonance Imaging (MRI), Computed Tomography, Positron Emission Tomography (PET), and ultrasound, provides a comprehensive view of the patient health status. Each of these methods contributes unique diagnostic insights, enhancing the overall assessment of patient condition. Nevertheless, the amalgamation of data from multiple modalities presents difficulties due to disparities in resolution, data collection methods, and noise levels. While traditional models like Convolutional Neural Networks (CNNs) excel in single-modality tasks, they struggle to handle multi-modal complexities, lacking the capacity to model global relationships. This research presents a novel approach for… More >