Yu Xiao1,2,#, Jianping Jiang3,#, Yan Chen1,4, Yi Huang1, Changyuan Wei1,*
Oncologie, Vol.24, No.4, pp. 729-742, 2022, DOI:10.32604/oncologie.2022.026118
Abstract Background: Immunotherapy is becoming a powerful approach in the treatment of breast cancer. However, high
response rates in the majority of breast cancer patients have yet to be achieved. Materials and Methods: Based on public
data sources, we identified 22 genes that are correlated with PD-1 expression as well as differentially expressed between
tumor tissues and normal tissues, and high expression of all the key genes was correlated with a superior survival outcome.
Using the least absolute shrinkage and selection operator Cox regression model, a risk score was constructed. Results: A
multivariate Cox analysis showed that the constructed risk score… More >
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