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  • Open Access

    ARTICLE

    Incidence, genomic diversity, and evolution of strawberry mottle virus in China

    LINGJIAO FAN, CHENGYONG HE, MENGMENG WU, DEHANG GAO, ZHENFEI DONG, SHENGFAN HOU, ZEKUN FENG, HONGQING WANG*

    BIOCELL, Vol.45, No.4, pp. 1137-1151, 2021, DOI:10.32604/biocell.2021.015396

    Abstract Strawberry mottle virus (SMoV) is one of the most common viruses infecting strawberries, causing losses to fruit yield and quality. In this study, 165 strawberry leaf samples were collected from six provinces of China, 46 of which tested positive for SMoV. The complete genome sequences of 11 SMoV isolates were obtained from Liaoning (DGHY3, DGHY16-2, DGHY17, DGHY20-2, DGHY21, DGHY26-2), Shandong (SDHY1, SDHY5, SDHY31-2, SDHY33-2), and Beijing (BJMX7). The RNA1 and RNA2 nucleotide identities between the 11 Chinese isolates were 95.4–99.3% and 96.3–99.6%, respectively, and they shared 78.4–96.6% and 84.8–93.5% identities with the available SMoV isolates in GenBank. Recombination analysis revealed… More >

  • Open Access

    ARTICLE

    Épidémiologie des tumeurs neuroendocrines intestinales *
    Epidemiology of Neuroendrocine Intestinal Tumours

    C. Lepage

    Oncologie, Vol.21, No.2, pp. 113-117, 2019, DOI:10.3166/onco-2019-0051

    Abstract Little is known about the epidemiology of digestive neuroendocrine tumours (NETs). NETs remain a rare cancer, representing 1% of all digestive cancers. In France, incidence rates are estimated to around 1.1/100,000 inhabitants in males and 0.9/100,000 in females. The incidence rates got increased over time, with probably more than 1,000 new cases per year in France. Because of their relatively good prognosis, NETs are the second more prevalent digestive cancer after colorectal cancer. Most digestive NETs are well-differentiated (WDNETs); poorly differentiated neuroendocrine carcinomas (PDNEC) account for less than 20% of the cases in most of the series. Among bowel-NETs, the… More >

  • Open Access

    ARTICLE

    Emotional and Behavioral Problems of Left-Behind Children in Impoverished Rural China: A Comparative Cross-Sectional Study of First Grade Junior High School

    Yuming Zhou1, Chunxia Zhao2, Fan He1, Xiaobo Tian2, Yi Zheng1,*, Jing Sun3,*

    International Journal of Mental Health Promotion, Vol.23, No.1, pp. 1-13, 2021, DOI:10.32604/IJMHP.2020.013093

    Abstract Objective: To investigate the prevalence of emotional and behavioral problems and related factors of left-behind children in impoverished rural China (mainly in the first grade of junior high school). Methods: A cross-sectional survey of rural households in 27 poverty-stricken counties in 12 provinces across China was conducted using the Strengths and Difficulties Questionnaire (SDQ). Results: The prevalence of emotional and behavioral problems in left-behind children was 11.7%, and that of non-left-behind children was 8.9%. There was statistical difference between the two groups (P < 0.01). There are no differences between the two groups in terms of the various factors of… More >

  • Open Access

    ARTICLE

    Percutaneous Closure of Patent Foramen Ovale and Secundum Atrial Septal Defects with the GORE® CARDIOFORM Septal Occluder: Incidence and Implications of Device Wire Frame Fracture

    Biagio Castaldi1,*, Giulio Cabrelle1, Massimo Padalino2, Vladimiro Vida2, Ornella Milanesi1, Giovanni Di Salvo1

    Congenital Heart Disease, Vol.15, No.5, pp. 347-360, 2020, DOI:10.32604/CHD.2020.012750

    Abstract Background: Trans-catheter closure has become the treatment of choice for patent foramen ovale (PFO) and ostium secundum atrial septal defects (ASD). A wide variety of devices are commercially available, however, concerns have been raised about the risk of cardiac erosion associated with stiff/rigid devices. The GORE® CARDIOFORM Septal Occluder (GSO) is a double-disc, soft and conformable device with no reported incidence of cardiac erosions. However, wire frame fracture (WFF) have been reported. Aim: To assess the incidence and clinical significance of WFF after GSO implantation in paediatric patients. Methods: Seventy-seven consecutive patients were enrolled. Periprocedural and follow-up assessments included clinical,… More >

  • Open Access

    ARTICLE

    Atrial Septal Defect in Children: The Incidence and Risk Factors for Diagnosis

    Gustaf Tanghöj1,*, Anna Lindam2, Petru Liuba3,4, Gunnar Sjöberg5, Estelle Naumburg1

    Congenital Heart Disease, Vol.15, No.5, pp. 287-299, 2020, DOI:10.32604/CHD.2020.011977

    Abstract Objective: Secundum atrial septal defect (ASD II) is a common congenital heart defect, and interatrial communications among preterm children is even more common. The objective of this study was to calculate the incidence of ASD II in children, with assessment to gestational age at birth. Further, to assess maternal, prenatal and postnatal risk factors associated with ASD II among children of different gestational age at birth. Design: This national registry based retrospective incidence study was supplemented with a national case-control study, using the Swedish Register of Congenial Heart Disease, Swedish Medical Birth Register and Statistics Sweden. All children, 0–18 years… More >

  • Open Access

    ARTICLE

    Incidence, Risk Factors, and Outcomes of Hyperferritinemia after Pediatric Cardiac Surgery with Cardiopulmonary Bypass: A Retrospective Study

    Shengwen Guo, Yuanyuan Tong, Liting Bai, Peiyao Zhang, Xin Duan*, Jinping Liu*

    Congenital Heart Disease, Vol.15, No.5, pp. 275-285, 2020, DOI:10.32604/CHD.2020.011894

    Abstract Objective: Serum ferritin has been identified as a prognostic marker in patients with a variety of diseases. In the present study we aim to determine the prevalence of risk factors and outcomes for hyperferritinemia in children undergoing cardiac surgery with cardiopulmonary bypass for congenital heart defects. Methods: The serum ferritin levels of 457 children between the ages of twentyeight days and three years undergoing cardiopulmonary bypass surgery between June 1, 2017 and June 1, 2018 were analyzed. The prevalence of early postoperative hyperferritinemia was investigated; hyperferritinemia was defined as a ferritin level ≥250 ng/ml. Multivariable regression models including candidate risk… More >

  • Open Access

    ARTICLE

    Structure-Preserving Dynamics of Stochastic Epidemic Model with the Saturated Incidence Rate

    Wasfi Shatanawi1, 2, 3, Muhammad Shoaib Arif4, *, Ali Raza4, Muhammad Rafiq5, Mairaj Bibi6, Javeria Nawaz Abbasi6

    CMC-Computers, Materials & Continua, Vol.64, No.2, pp. 797-811, 2020, DOI:10.32604/cmc.2020.010759

    Abstract The structure-preserving features of the nonlinear stochastic models are positivity, dynamical consistency and boundedness. These features have a significant role in different fields of computational biology and many more. Unfortunately, the existing stochastic approaches in literature do not restore aforesaid structure-preserving features, particularly for the stochastic models. Therefore, these gaps should be occupied up in literature, by constructing the structure-preserving features preserving numerical approach. This writing aims to describe the structure-preserving dynamics of the stochastic model. We have analysed the effect of reproduction number in stochastic modelling the same as described in the literature for deterministic modelling. The usual explicit… More >

  • Open Access

    ARTICLE

    Incidence, morphology, and progression of bicuspid aortic valve in pediatric and young adult subjects with coexisting congenital heart defects

    Talha Niaz1, Joseph T. Poterucha1, Jonathan N. Johnson1,2, Cecilia Craviari1, Thomas Nienaber1, Jared Palfreeman1, Frank Cetta1,2, Donald J. Hagler1,2

    Congenital Heart Disease, Vol.12, No.3, pp. 261-269, 2017, DOI:10.1111/chd.12429

    Abstract Background: Bicuspid aortic valve (BAV) occurs both as an isolated cardiac lesion and in association with congenital heart defects (CHD). Their aim was to identify the incidence and morphology of BAV in patients with coexisting CHD and compare their disease progression to patients with isolated BAV.
    Methods: The Mayo Clinic echocardiography database was retrospectively analyzed to identify pediatric and young adult patients (≤22 years) who were diagnosed with BAV from 1990 to 2015. The morphology of BAV was determined from the echocardiographic studies before any intervention.
    Results: Overall, 1010 patients with BAV were identified, 619 (61%) with isolated BAV and… More >

  • Open Access

    ARTICLE

    Increased incidence of infective endocarditis in patients with ventricular septal defect

    Phong Teck Lee, Felix Maverick Uy, Jie Sheng Foo, Ju Le Tan

    Congenital Heart Disease, Vol.13, No.6, pp. 1005-1011, 2018, DOI:10.1111/chd.12667

    Abstract Background: Ventricular septal defect (VSD) is one of the most common congenital heart anomalies in childhood and there is an increasing prevalence of VSDs in the adult population. The long‐term risk of infective endocarditis (IE) is of concern. The aim of this study was to clarify and compare the incidence of IE in adults with re‐ paired and unrepaired VSDs.
    Methods: Patients with VSDs were identified using the Adult Congenital Heart Disease registry at the National Heart Centre Singapore. Patients were divided into Group 1 (repaired VSD) and Group 2 (unrepaired VSDs). The electronic medical re‐ cords were searched for… More >

  • Open Access

    ARTICLE

    Incidence and factors influencing the spontaneous closure of Fontan fenestration

    Sudheer R. Gorla1, Nataley K. Jhingoeri1, Abhishek Chakraborty1, Kishore R. Raja1, Ashish Garg1, Satinder Sandhu1, Eliot R. Rosenkranz2, Sethuraman Swaminathan1

    Congenital Heart Disease, Vol.13, No.5, pp. 776-781, 2018, DOI:10.1111/chd.12652

    Abstract Introduction: The Fontan operation is the final stage of single ventricle palliation in patients with complex congenital heart disease. Fenestration in the Fontan conduit, providing an atrial level right to left shunt, has been shown to reduce early postoperative morbidity. However, there is limited data on the long‐term fate of this fenestration. The aim of this study is to define the rate of spontaneous closure of the fenestration in the Fontan conduit and factors predictive of the fate of the fenestration.
    Methods: This was a retrospective study reviewing the medical records of the patients who underwent fenestrated Fontan operation at… More >

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