YAO FANG^1,2,#, FEI XIA^1,#, FEIFEI TIAN³, LEI QU¹, FANG YANG¹, JUAN FANG^1,2, ZHENHONG HU^1,*, HAICHAO LIU^1,*

BIOCELL, Vol.48, No.4, pp. 613-621, 2024, DOI:10.32604/biocell.2024.031539 - 09 April 2024

Abstract Objective: In the realm of Class I pathogens, Burkholderia pseudomallei (BP) stands out for its propensity to induce severe pathogenicity. Investigating the intricate interactions between BP and host cells is imperative for comprehending the dynamics of BP infection and discerning biomarkers indicative of the host cell response process. Methods: mRNA extraction from BP-infected mouse macrophages constituted the initial step of our study. Employing gene expression arrays, the extracted RNA underwent conversion into digital signals. The percentile shift method facilitated data processing, with the identification of genes manifesting significant differences accomplished through the application of the t-test. Subsequently,… More >

Rana Muhammad Zulqarnain¹, Hafiz Khalil ur Rehman², Imran Siddique³, Hijaz Ahmad^4,5, Sameh Askar⁶, Shahid Hussain Gurmani^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 1863-1892, 2024, DOI:10.32604/cmes.2023.031480 - 29 January 2024

Abstract This research is devoted to diagnosing water-borne infectious diseases caused by floods employing a novel diagnosis approach, the Einstein hybrid structure of q-rung orthopair fuzzy soft set. This approach integrates parts of fuzzy logic and soft set theory to develop a robust alternative for disease detection in stressful situations, especially in areas affected by floods. Compared to the traditional intuitionistic fuzzy soft set and Pythagorean fuzzy soft set, the q-rung orthopair fuzzy soft set (q-ROFSS) adequately incorporates unclear and indeterminate facts. The major objective of this investigation is to formulate the q-rung orthopair fuzzy soft… More >

Tariq Abdul Hamid¹, Amr Elmekresh¹, Almas Zulfiquar Parkar², Mohamad Motaz Al Masri¹, Yaser Saeedi¹

Canadian Journal of Urology, Vol.30, No.3, pp. 11562-11567, 2023

Abstract Monkeypox virus (MPV) is a rare zoonotic infection caused by an orthopoxvirus. The sudden outbreak of more than 3000 MPV infection from 50 countries has led the WHO to declare the infection as an “evolving threat of moderate public health concern”. Here, we describe a case series of two cases of the MPV with a similar onset of cutaneous lesions in the genital area but with different progression in 35 and 41-year-old males respectively. Both of our patients were reported heterosexual with a 10-day prior history of unprotected sexual activity with a sex worker. Case… More >

Maxwell Sandberg¹, Wyatt Whitman¹, Janmejay Hingu¹, Parth Thakker¹, Anita Rong², Caleb Bercu², Jacob Greenberg³, Ronald Davis III¹, Ashok Hemal¹, Matvey Tsivian¹

Canadian Journal of Urology, Vol.30, No.4, pp. 11599-11604, 2023

Abstract Introduction: There is an ongoing debate as to the appropriate regimen of antibiotic prophylaxis with transperineal (TP) biopsy. The objective of this study was to report the rate of infection following TP biopsy at a high-volume institution and assess the impact of single dose antibiotics at the time of biopsy versus outpatient antibiotics in preventing postprocedural infections.
Materials and methods: Records of men undergoing TP prostate biopsy from 2012 to 2022 were reviewed. Patients were divided into two groups, those who received single dose intravenous (IV) antibiotics at the time of biopsy (n = 440) and those… More >

FATEMEH HEIDARI^1,2, REIHANEH SEYEDEBRAHIMI^1,2, PIAO YANG³, MOHSEN ESLAMI FARSANI^1,2, SHIMA ABABZADEH^2,4, NASER KALHOR⁵, HAMED MANOOCHEHRI⁶, MOHSEN SHEYKHHASAN^7,*, MARYAM AZIMZADEH^8,9,*

BIOCELL, Vol.47, No.12, pp. 2597-2608, 2023, DOI:10.32604/biocell.2023.043351 - 27 December 2023

Abstract Exosomes are small vesicles that carry molecules from one cell to another. They have many features that make them interesting for research, such as their stability, low immunogenicity, size of the nanoscale, toxicity, and selective delivery. Exosomes can also interact with viruses in diverse ways. Emerging research highlights the significant role of exosomes in viral infections, particularly in the context of diseases like COVID-19, HIV, HBV and HCV. Understanding the intricate interplay between exosomes and the human immune system holds great promise for the development of effective antiviral therapies. An important aspect is gaining clarity More >

YINGDONG ZHANG^1,2, MING CHU^1,2,*, HONGZHOU LU^3,*

BIOCELL, Vol.47, No.12, pp. 2591-2595, 2023, DOI:10.32604/biocell.2023.030331 - 27 December 2023

Abstract Human immunodeficiency virus (HIV) infection of the central nervous system (CNS) has attracted significant attention because it contributes to severe complications of acquired immunodeficiency syndrome (AIDS) and seriously impairs the life quality of infected patients. In this review, we briefly describe the latent infection of HIV in CNS and focus on the role of the important immune cells, such as T cells, in the formation and maintenance of the HIV reservoir in CNS. This review explores the mechanisms by which T cells enter CNS and establish latent infection of HIV in the CNS. In conclusion, More > Graphic Abstract

XIWEI ZHAO^1,#, JINSONG WANG^1,2,#, YIFAN XU¹, JIAN ZHOU^5,*, LEI HU^1,3,4,*

BIOCELL, Vol.47, No.7, pp. 1431-1438, 2023, DOI:10.32604/biocell.2023.028217 - 21 June 2023

Abstract Atherosclerotic cardiovascular disease (ASCVD) includes a group of disorders of the heart and blood vessels and accounts for major morbidity and premature death worldwide. Periodontitis is a chronic inflammatory disease with the gradual destruction of supporting tissues around the teeth, including gingiva, periodontal ligament, alveolar bone, and cementum. Periodontitis has been found to potentially increase the risk of ASCVD. Generally, oral microorganisms and inflammation are the major factors for periodontitis to the incidence of ASCVD. Recently, evidence has shown that the loss of masticatory function is another important factor of periodontitis to the incidence of More > Graphic Abstract

Shroog Alshomrani^*, Muhammad Arif, Mohammed A. Al Ghamdi

CMC-Computers, Materials & Continua, Vol.75, No.3, pp. 5717-5742, 2023, DOI:10.32604/cmc.2023.038059 - 29 April 2023

Abstract Coronavirus has infected more than 753 million people, ranging in severity from one person to another, where more than six million infected people died worldwide. Computer-aided diagnostic (CAD) with artificial intelligence (AI) showed outstanding performance in effectively diagnosing this virus in real-time. Computed tomography is a complementary diagnostic tool to clarify the damage of COVID-19 in the lungs even before symptoms appear in patients. This paper conducts a systematic literature review of deep learning methods for classifying the segmentation of COVID-19 infection in the lungs. We used the methodology of systematic reviews and meta-analyses (PRISMA) More >

Sobia Nawaz¹, Sidra Rasheed², Wania Sami³, Lal Hussain^4,5,*, Amjad Aldweesh^6,*, Elsayed Tag eldin⁷, Umair Ahmad Salaria^8,9, Mohammad Shahbaz Khan¹⁰

CMC-Computers, Materials & Continua, Vol.75, No.3, pp. 5213-5228, 2023, DOI:10.32604/cmc.2023.037543 - 29 April 2023

Abstract This study is designed to develop Artificial Intelligence (AI) based analysis tool that could accurately detect COVID-19 lung infections based on portable chest x-rays (CXRs). The frontline physicians and radiologists suffer from grand challenges for COVID-19 pandemic due to the suboptimal image quality and the large volume of CXRs. In this study, AI-based analysis tools were developed that can precisely classify COVID-19 lung infection. Publicly available datasets of COVID-19 (N = 1525), non-COVID-19 normal (N = 1525), viral pneumonia (N = 1342) and bacterial pneumonia (N = 2521) from the Italian Society of Medical and… More >

Yeyao Du^1,#, Ye Zhang^2,#, Yang Song¹, Zhuo Zhang¹, Sujie Fan¹, Hanzhu Zhang¹, Piwu Wang^1,*

Phyton-International Journal of Experimental Botany, Vol.92, No.6, pp. 1907-1920, 2023, DOI:10.32604/phyton.2023.027607 - 11 April 2023

Abstract Soybean (Glycine max (Linn.) Merr.) annual leguminous crop is cultivated all over the world. The occurrence of diseases has a great impact on the yield and quality of soybean. In this study, based on the RNA-seq of soybean variety M18, a complete CDS (Coding sequence) GmPR1L of the pathogenesis-related protein 1 family was obtained, which has the ability to resist fungal diseases. The overexpression vector and interference expression vector were transferred into tobacco NC89, and the resistance of transgenic tobacco (Nicotiana tabacum L.) to Botrytis cinerea infection was identified. The results show that: Compared with the control, the activities… More >