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  • Open Access

    ARTICLE

    Efficient Numerical Scheme for the Solution of HIV Infection CD4+ T-Cells Using Haar Wavelet Technique

    Rohul Amin1, Şuayip Yüzbası2,*, Shah Nazir3

    CMES-Computer Modeling in Engineering & Sciences, Vol.131, No.2, pp. 639-653, 2022, DOI:10.32604/cmes.2022.019154

    Abstract In this paper, Haar collocation algorithm is developed for the solution of first-order of HIV infection CD4+ T-Cells model. In this technique, the derivative in the nonlinear model is approximated by utilizing Haar functions. The value of the unknown function is obtained by the process of integration. Error estimation is also discussed, which aims to reduce the error of numerical solutions. The numerical results show that the method is simply applicable. The results are compared with Runge-Kutta technique, Bessel collocation technique, LADM-Pade and Galerkin technique available in the literature. The results show that the Haar technique is easy, precise and… More >

  • Open Access

    ARTICLE

    COVID-19 Severity Prediction Using Enhanced Whale with Salp Swarm Feature Classification

    Nebojsa Budimirovic1, E. Prabhu2, Milos Antonijevic1, Miodrag Zivkovic1, Nebojsa Bacanin1,*, Ivana Strumberger1, K. Venkatachalam3

    CMC-Computers, Materials & Continua, Vol.72, No.1, pp. 1685-1698, 2022, DOI:10.32604/cmc.2022.023418

    Abstract Computerized tomography (CT) scans and X-rays play an important role in the diagnosis of COVID-19 and pneumonia. On the basis of the image analysis results of chest CT and X-rays, the severity of lung infection is monitored using a tool. Many researchers have done in diagnosis of lung infection in an accurate and efficient takes lot of time and inefficient. To overcome these issues, our proposed study implements four cascaded stages. First, for pre-processing, a mean filter is used. Second, texture feature extraction uses principal component analysis (PCA). Third, a modified whale optimization algorithm is used (MWOA) for a feature… More >

  • Open Access

    ARTICLE

    Transcriptome Profiling of Barley Cultivar Hua 30 MDEC in Response to Agrobacterium Infection

    Yingbo Li1,2,#, Ting He1,2,#, Guimei Guo1,2, Hongwei Xu1,2, Yingjie Zong1,2, Shuwei Zhang1,2, Ruiju Lu1,2, Longhua Zhou1,2,*, Chenghong Liu1,2,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.6, pp. 1153-1164, 2022, DOI:10.32604/phyton.2022.019520

    Abstract Agrobacterium-mediated transformation has been widely used in plants. However, the mechanism in plant cells’ response to Agrobacterium infection was very complex. The mechanism of the determinants in host cell remains obscure, especially in barley, which is recalcitrant for Agrobacterium-mediated transformation. In the present study, microspore-derived embryogenic calli (MDEC) from barley elite cultivar were employed as unique subjects to characterize the mechanisms during the Agrobacterium infection process. Hua 30 MDEC can be successfully infected by Agrobacterium. RNA-sequencing at different infection points (0, 2, 6, 12, 24 hpi) was performed. The average expressional intensity of the whole genomics increased from 0 to… More >

  • Open Access

    ARTICLE

    Should we continue breastfeeding after SARS-CoV-2 infection or mRNA vaccination?

    FEI CHEN1,*, CHUN LUAN1, ZICHUN WEI1, DECHEN CAI1, ZHIWEN CUI1, YUYANG LI1, HAO WU2, XIAOXIA ZHANG1, XIAOLI WU2

    BIOCELL, Vol.46, No.6, pp. 1425-1433, 2022, DOI:10.32604/biocell.2022.019868

    Abstract The coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has posed a potential threat to infant health. The World Health Organization recommended that the benefits of breastfeeding far outweigh the potential risk of transmission, but there is no denying that the current evidence is insufficient. Moreover, although the COVID-19 mRNA vaccine has played an effective role in protection against infection, individuals have increasing concerns about the safety of breastfeeding after vaccination, and which have caused some breastfeeding women to postpone vaccination or stop breastfeeding early. Thus, in this review, we provide an in-depth… More >

  • Open Access

    ARTICLE

    Acute exacerbation of chronic obstructive pulmonary disease was associated with respiratory syncytial virus infection and the upregulation of TLR3

    LING GONG1, HUAJUN YANG1, YING HUANG2, ZHU LI1, JIN NIE3, MENG YE4, PENG XIE5, DAISHUN LIU2,*

    BIOCELL, Vol.46, No.4, pp. 1025-1032, 2022, DOI:10.32604/biocell.2022.018248

    Abstract Respiratory syncytial virus (RSV) infection is known as a risk factor for chronic obstructive pulmonary disease (COPD). RSV infection induces the upregulation of Toll-like receptor 3 (TLR3). This study aimed to investigate the association of TLR3 with RSV induced acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Serum/sputum samples from AECOPD patients, stable chronic obstructive pulmonary disease (SCOPD) patients, and healthy controls were collected. Nested PCR was used to detect RSV. The lung function parameters were assessed by blood gas and lung function analysis. The expression levels of inflammatory factors in sputum and serum samples were determined by enzyme-linked immunosorbent… More >

  • Open Access

    ARTICLE

    The Mathematical Model for Streptococcus suis Infection in Pig-Human Population with Humidity Effect

    Inthira Chaiya1, Kamonchat Trachoo1, Kamsing Nonlaopon2, Din Prathumwan2,*

    CMC-Computers, Materials & Continua, Vol.71, No.2, pp. 2981-2998, 2022, DOI:10.32604/cmc.2022.021856

    Abstract In this paper, we developed a mathematical model for Streptococcus suis, which is an epidemic by considering the moisture that affects the infection. The disease is caused by Streptococcus suis infection found in pigs which can be transmitted to humans. The patients of Streptococcus suis were generally found in adults males and the elderly who contacted pigs or who ate uncooked pork. In human cases, the infection can cause a severe illness and death. This disease has an impact to the financial losses in the swine industry. In the development of models for this disease, we have divided the population… More >

  • Open Access

    ARTICLE

    A Novel COVID-19 Prediction Model with Optimal Control Rates

    Ashraf Ahmed1, Yousef AbuHour2,*, Ammar El-Hassan1

    Intelligent Automation & Soft Computing, Vol.32, No.2, pp. 979-990, 2022, DOI:10.32604/iasc.2022.020726

    Abstract The Corona (COVID-19) epidemic has triggered interest in many fields of technology, medicine, science, and politics. Most of the mathematical research in this area focused on analyzing the dynamics of the spread of the virus. In this article, after a review of some current methodologies, a non-linear system of differential equations is developed to model the spread of COVID-19. In order to consider a wide spectrum of scenarios, we propose a susceptible-exposed-infected-quarantined-recovered (SEIQRS)-model which was analyzed to determine threshold conditions for its stability, and the number of infected cases that is an infected person will transmit on a virus to,… More >

  • Open Access

    ARTICLE

    Analyzing the Implications of COVID-19 Pandemic through an Intelligent-Computing Technique

    Abhishek Kumar Pandey1, Jehad F. Al-Amri2, Ahmad F. Subahi3, Rajeev Kumar4,*, Raees Ahmad Khan1

    Computer Systems Science and Engineering, Vol.41, No.3, pp. 959-974, 2022, DOI:10.32604/csse.2022.021443

    Abstract The outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 virus or COVID-19) disease was declared pandemic by the World Health Organization (WHO) on March 11, 2020. COVID-19 has already affected more than 211 nations. In such a bleak scenario, it becomes imperative to analyze and identify those regions in Saudi Arabia that are at high risk. A preemptive study done in the context of predicting the possible COVID-19 hotspots would facilitate in the implementation of prompt and targeted countermeasures against SARS-CoV-2, thus saving many lives. Working towards this intent, the present study adopts a decision making based methodology of… More >

  • Open Access

    ARTICLE

    Proteome-wide screening for the analysis of protein targeting of Chlamydia pneumoniae in endoplasmic reticulum of host cells and their possible implication in lung cancer development

    YANYAN LI1, SHAHANAVAJ KHAN2,3,4, ANIS AHMAD CHAUDHARY5, HASSAN AHMED RUDAYNI5, ABDUL MALIK2, ASHWAG SHAMI6

    BIOCELL, Vol.46, No.1, pp. 87-95, 2022, DOI:10.32604/biocell.2022.016509

    Abstract Available reports have confirmed a link between bacterial infection and the progression of different types of cancers, including colon, lungs, and prostate cancer. Here we report the Chlamydia pneumonia proteins targeting in endoplasmic reticulum (ER) using in-silico approaches and their possible role in lung cancer etiology. We predicted 48 proteins that target human ER, which may be associated with protein folding and protein-protein interactions during infection. The results showed C. pneumoniae proteins targeting human ER and their implications in lung cancer growth. These targeted proteins may be involved in competitive interactions between host and bacterial proteins, which may change the… More >

  • Open Access

    REVIEW

    Dengue virus infection: A review of advances in the emerging rapid detection methods

    MUBASHIR HUSSAIN1, ZEESHAN ALI1, BIN LIU2, JIANGUO DAI1, XIAOLONG LIU1, JUNCHEN ZHU1, YONGJUN TANG1

    BIOCELL, Vol.46, No.1, pp. 61-74, 2022, DOI:10.32604/biocell.2022.016392

    Abstract Dengue virus infections are increasing worldwide generally and in Asia, Central and South America and Africa, particularly. It poses a serious threat to the children population. The rapid and accurate diagnostic systems are essentially required due to lack of effective vaccine against dengue virus and the progressive spread of the dengue virus infection. The recent progress in developing micro- and nano-fabrication techniques has led to low cost and scale down the biomedical point-of-care devices. Starting from the conventional and modern available methods for the diagnosis of dengue infection, this review examines several emerging rapid and point-of-care diagnostic devices that hold… More >

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