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  • Open Access

    REVIEW

    Changes in Phyto-Chemical Status upon Viral Infections in Plant: A Critical Review

    Tehmina Bahar1,*, Adeeba Mahboob Qureshi1, Fasiha Qurashi1,2, Muniba Abid1, Misbah Batool Zahra1, Muhammad Saleem Haider1

    Phyton-International Journal of Experimental Botany, Vol.90, No.1, pp. 75-86, 2021, DOI:10.32604/phyton.2020.010597 - 20 November 2020

    Abstract Most damaging plant diseases have been caused by viruses in the entire world. In tropical and subtropical areas, the damage caused by plant virus leads to great economic and agricultural losses. Single stranded DNA viruses (geminiviruses) are the most perilous pathogens which are responsible for major diseases in agronomic and horticultural crops. Significantly begomoviruses and mastreviruses are the biggest genus of plant infecting viruses, transmitted though Bemisia tabaci and members of Cicadellidae respectively. Plants possesses some naturally existing chemicals term as phyto-chemicals which perform important functions in the plant. Some antioxidant enzymes are used by plants for… More >

  • Open Access

    ARTICLE

    Hospital-specific antibiograms and antibiotic prophylaxis for prostate biopsies: a reexamination of AUA recommendations

    Mark Mann1, Brian P. Calio1, James Ryan Mark1, Raju Chelluri2, Erich Hufnagel3, Adam Reese4, Costas D. Lallas1, Edouard J. Trabulsi1, Thenappan Chandrasekar1, Patrick J. Shenot1, Ethan Halpern5, Leonard G. Gomella1

    Canadian Journal of Urology, Vol.27, No.1, pp. 10099-10104, 2020

    Abstract Introduction: To assess whether standard American Urological Association (AUA) and other recommendations for prostate biopsy prophylaxis provide sufficient coverage of common urinary organisms responsible for post biopsy infections by comparing local antibiograms in Philadelphia-area hospitals.
    Materials and methods: De-identified culture results derived from antibiograms were collected from six academic and community hospitals in the Philadelphia region. Analysis specifically focused on four major bacterial causes of urinary tract infection following prostate biopsy (Escherichia coli (E. coli), Klebsiella pneumoniae, Proteus mirabilis and Enterococcus faecalis) along with commonly recommended antibiotics including fluoroquinolones (FQ’s), trimethoprim/sulfamethoxazole, ceftriaxone, and gentamicin.
    Results: Bacterial sensitivities to… More >

  • Open Access

    ARTICLE

    Intermittent catheterization and urinary tract infection in multiple sclerosis patients

    Lauren E. Corona1, Nadia R. Sion2, Anne P. Cameron1, Paholo G. Barboglio Romo1, John T. Stoffel1

    Canadian Journal of Urology, Vol.27, No.4, pp. 10294-10299, 2020

    Abstract Introduction: We sought to investigate whether starting clean intermittent catheterization (CIC) for multiple sclerosis (MS) patients with lower urinary tract symptoms (LUTS) and elevated post-void residual (PVR) would improve urinary quality of life (QoL) and decrease risk of urinary tract infection (UTI).
    Materials and methods: We retrospectively reviewed an institutional database for MS patients with PVR > 100 mL and obstructive LUTS. Patients were categorized by subsequent choice of treatment: CIC versus medical treatment. Outcomes compared over 1-year follow up included incidence of UTI, urinary QoL, emergency room visits, and adherence to therapy.
    Results: Between 2014 and 2017,… More >

  • Open Access

    HOW I DO IT

    Next-generation DNA sequencing for infected genitourinary implants: How I do it

    Paul H. Chung, Joon Yau Leong, Seth Teplitsky, Patrick J. Shenot, Akhil K. Das, Leonard G. Gomella

    Canadian Journal of Urology, Vol.27, No.5, pp. 10418-10423, 2020

    Abstract Infection of artificial urinary sphincters or inflatable penile prostheses is one of the most devastating complications after prosthetic surgery and can have a significant impact on a quality of life. Patients undergoing revision surgery with or without device replacement may have increased risk for infection when compared to initial primary surgery. As such, surgeons may utilize traditional culture results to direct antimicrobial therapy for these patients. Unfortunately, culture results can be inconclusive in up to one-third of the time even in the setting of active device infection. Next-generation sequencing (NGS) of DNA is an emerging More >

  • Open Access

    COMMENTARY

    Do antibiotics cause AUS infections?

    Jack M. Zuckerman

    Canadian Journal of Urology, Vol.27, No.6, pp. 10443-10443, 2020

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Are postoperative antibiotics necessary after artificial urinary sphincter insertion?

    Benjamin M. Dropkin1, Jeremiah D. Dallmer2, Leah P. Chisholm2, Niels V. Johnsen1, Roger R. Dmochowski1, Douglas F. Milam1, Melissa R. Kaufman1

    Canadian Journal of Urology, Vol.27, No.6, pp. 10437-10442, 2020

    Abstract Introduction: We sought to explore whether patients discharged without antibiotics after artificial urinary sphincter (AUS) insertion were more likely to require device explantation for infection or erosion compared to patients discharged with antibiotics at our institution and compared to patients in other large, contemporary series.
    Materials and methods: AUS insertions performed at our institution between 2013 and 2017 were retrospectively reviewed to determine demographics, comorbidities, and perioperative and medium-term outcomes. Patients were grouped based on 1) known risk factors for infectious complications or erosion and 2) postoperative antibiotic prescription status. Patients were placed in Group 1 if… More >

  • Open Access

    ARTICLE

    Phytohormonal and metabolism analysis of Brassica rapa L. ssp. pekinensis with different resistance during Plasmodiophora brassicae infection

    MEI LAN#, JINGFENG HU#, HONGLI YANG, LIQIN ZHANG, XUEZHONG XU, JIANGMING HE*

    BIOCELL, Vol.44, No.4, pp. 751-767, 2020, DOI:10.32604/biocell.2020.012954 - 24 December 2020

    Abstract Clubroot of Chinese cabbage (Brassica rapa L. ssp. pekinensis), caused by the obligate parasite Plasmodiophora brassicae, accounts for serious yield losses. The aim of our study was to explore the phytohormone levels and metabolome changes in the roots of resistant and susceptible B. rapa genotypes at a late stage of infection, i.e., 28 days post-infection. Both genotypes showed decreased auxin levels after P. brassicae infection except for indole-3-acetic acid. Overall, the susceptible genotype had higher auxin and cytokinin levels after infection, with the exception of trans-zeatin and 3- indolebutyric acid as compared to the resistant genotype. Jasmonic acid levels declined… More >

  • Open Access

    ARTICLE

    Managing the Adult Congenital Heart Disease Patient in the COVID-19 Pandemic—A New York Perspective

    Jodi L. Feinberg1, Frank Cecchin1,2, Arianna Gonzalez1, Emily Johnson2, Dan G. Halpern1,*

    Congenital Heart Disease, Vol.15, No.3, pp. 141-146, 2020, DOI:10.32604/CHD.2020.012039 - 15 July 2020

    Abstract Adults with congenital heart disease (ACHD) are likely at increased risk for complications of COVID-19. ACHD centers should prepare to deliver routine cardiac care and support for patients with COVID-19 safely at home, as the number of COVID-19 infections worldwide continues to increase. This brief report aims to share the strategies we have used in our ACHD program to manage and treat our patients during this global health crisis at one of the initial epicenters of the pandemic in New York City, and offer suggestions for preparation for ACHD clinicians. More >

  • Open Access

    ARTICLE

    Detection of new antibiotic resistance gene profile in Escherichia coli associated with avian leukosis virus infection from broiler chickens

    HAIFENG WANG1,2,*, JUAN GUO1, LIJING ZHENG1, SHUYING LIU1, ZHERONG WANG1, HONGXUAN HE2

    BIOCELL, Vol.44, No.2, pp. 217-224, 2020, DOI:10.32604/biocell.2020.09051 - 27 May 2020

    Abstract The Escherichia coli (E. coli) is prevailing worldwide, but the epidemiology of E. coli infections feature regional distribution characteristics to some extent. E. coli, as a zoonotic pathogen, can be transferred from animals to humans through food chain or via contact with wounds, causing a public health risk. We reported the swelling of proventriculus and tracheal bleeding following the death in two broiler chickens (Gallus gallus domesticus) from Beijing, China. To investigate whether a virus was involved in the infection, Madin Darby Bovine Kidney (MDCK) cells were co-cultured with supernatants of proventriculus, trachea and spleen homogenates. The avian leucosis virus… More >

  • Open Access

    ARTICLE

    Safflower (Carthamus Tinctorius L.) a Potential Source of Drugs against Cryptococcal Infections, Malaria and Leishmaniasis

    Aknur Turgumbayeva1,2, Gulbaram Ustenova1, Ubaidilla Datkhayev1, Khairolla Rahimov3, Silvijus Abramavicius4,5, Agile Tunaityte4,*, Kairat Zhakipbekov1,6, Kaldanay Kozhanova1, Saken Tulemissov7, OzikhanUstenova8, Gulmira Datkayeva9, Edgaras Stankevicius1,10

    Phyton-International Journal of Experimental Botany, Vol.89, No.1, pp. 137-146, 2020, DOI:10.32604/phyton.2020.07665 - 01 March 2020

    Abstract In this research we present that Carthamus Tinctorius L. (gen. Asteraceae, otherwise known as Safflower) (Fig. 1) may contain agents active in Cryptococcal infections, malaria and Leishmaniasis, as treatment options are becoming scarce due to drug resistance development. Phytochemistry and pharmacological activities (antimicrobial, antimalarial, antileishmanial) of C. tinctorius L. were analyzed. The composition of volatile oil of safflower dried flowers was analyzed by gas chromatography-mass spectrophotometry with flame ionization detector (GC-FID) and in vitro sensitivity assays were performed to assess biological activity. 8 known and 3 unknown compounds were detected in the extract (Fig. 1). Then the More >

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