Hitoshi Takamatsu^*1, Ken-ichi Yamamoto^*1, Nahoko Tomonobu^*, Hitoshi Murata^*, Yusuke Inoue^†, Akira Yamauchi^‡, I Wayan Sumardika^*§, Youyi Chen^*, Rie Kinoshita^*, Masahiro Yamamura^¶, Hideyo Fujiwara^#, Yosuke Mitsui^{*, **}, Kota Araki^*††, Junichiro Futami^‡‡, Ken Saito^§§, Hidekazu Iioka^§§, I Made Winarsa Ruma^§, Endy Widya Putranto^¶¶, Masahiro Nishibori^##, Eisaku Kondo^§§, Yasuhiko Yamamoto^***, Shinichi Toyooka^††, Masakiyo Sakaguchi^*

Oncology Research, Vol.27, No.6, pp. 713-727, 2019, DOI:10.3727/096504018X15433161908259

Abstract The fertile stroma in pancreatic ductal adenocarcinomas (PDACs) has been suspected to greatly contribute to PDAC progression. Since the main cell constituents of the stroma are fibroblasts, there is crosstalking(s) between PDAC cells and surrounding fibroblasts in the stroma, which induces a fibroblast proliferation burst. We have reported that several malignant cancer cells including PDAC cells secrete a pronounced level of S100A11, which in turn stimulates proliferation of cancer cells via the receptor for advanced glycation end products (RAGE) in an autocrine manner. Owing to the RAGE⁺ expression in fibroblasts, the extracellular abundant S100A11 will affect More >

Liliana Aguilar^∗, Salvador W. Nava-Díaz, Gabriel Chavira^†

Computer Systems Science and Engineering, Vol.34, No.5, pp. 297-303, 2019, DOI:10.32604/csse.2019.34.297

Abstract Natural ventilation is a component that provides a positive impact in the quality of air conditions in indoor environments, especially in non-industrial buildings. The maintenance of a continuous entrance of outside air through windows provides to the indoor a feasible and affordable manner to regulate and sustain low standards in theVOC (Volatile Organic Compounds). The technology and the Human Computer-Interaction have contributed to the creation of Intelligent Environments (EI) that provides to humans being a positive and non-intrusive responsiveness of the environment to improve their quality of life in daily activities. The Decision Trees for… More >

Erna Qi^1,∗, Min Deng²

Computer Systems Science and Engineering, Vol.34, No.4, pp. 237-248, 2019, DOI:10.32604/csse.2019.34.237

Abstract The application of computer technology, especially the emergence of some statistical software and graphic presentation technology, has enabled many areas of research that require a large amount of data analysis. This paper discusses the relationship between R&D investment and corporate financial performance, and further studies the effect of environmental regulations on this relationship through these technologies. The unbalanced panel data of listed companies from 2007 to 2016 were used as a sample, and then corresponding regression modelswere established through logical reasoning. Empirical analysis has found that there is an inverted U-shaped relationship between R&D investment… More >

Xueling Nie^1,∗, Xinlu Zou¹, Dishi Zhu²

Computer Systems Science and Engineering, Vol.34, No.4, pp. 207-214, 2019, DOI:10.32604/csse.2019.34.207

Abstract There are disadvantages such as lack of resources and experience in college students’ entrepreneurship and the current research belong to the investigation and research, lacking the prediction simulation model research. Based on the theory of individual learning and the theory of complex systems, this study analyzes the mechanism of college students’ entrepreneurial process through dynamic learning theory, establishes the model of college students’ entrepreneurial subject, studies the different learning styles of college students, and discusses the influence of environmental dynamics on college students’ chance recognition. Through simulation and practice analysis, it is concluded that college More >

Gregory Reimonn¹, Taofeng Lu¹, Neeti Gandhi², Wan-Ting Chen^1,*

Journal of Renewable Materials, Vol.7, No.12, pp. 1251-1268, 2019, DOI:10.32604/jrm.2019.08055

Abstract Microplastic pollution represents a side-effect stemming from a global plastic waste mismanagement problem and includes degraded particles or mass produced plastic particles less than 5 mm in largest dimension. The small nature of microplastics gives this area of pollution different environmental concerns than general plastic waste in the environment. The biological toxicity of particles, their internal components, and their surface level changes all present opportunities for these particles to adversely affect the environment around them. Thus, it is necessary to review the current literature surrounding this topic and identify areas where the study of microplastic More >

Guangyu Zhu¹, Yuan Wei¹, Qi Yuan^1,*, Ge Yan², Jian Yang²

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 55-56, 2019, DOI:10.32604/mcb.2019.05730

Abstract This article has no abstract. More >

Muyi Guo¹, Yan Cai¹, Zhiyong Li^1,2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 49-49, 2019, DOI:10.32604/mcb.2019.05727

Abstract Observational studies have identified angiogenesis from the adventitial vasa vasorum and intraplaque hemorrhage (IPH) as critical factors in atherosclerotic plaque progression and destabilization. Here we propose a mathematical model incorporating intraplaque neovascularization and hemodynamic calculation for the quantitative evaluation of atherosclerotic plaque hemorrhage. An angiogenic microvasculature based on histology of a patient’s carotid plaque is generated by two-dimensional nine-point model of endothelial cell migration. Three key cells (endothelial cells, smooth muscle cells and macrophages) and three key chemicals (vascular endothelial growth factors, extracellular matrix and matrix metalloproteinase) are involved in the intraplaque angiogenesis model, and… More >

Yuankun Yan^1,*, Yan Kong¹, Zhangjie Fu^1,2

Journal of Information Hiding and Privacy Protection, Vol.1, No.3, pp. 143-155, 2019, DOI:10.32604/jihpp.2019.07772

Abstract Nowadays, emergency accidents could happen at any time. The accidents occur unpredictably and the accidents requirements are diversely. The accidents happen in a dynamic environment and the resource should be cooperative to solve the accidents. Most methods are focusing on minimizing the casualties and property losses in a static environment. However, they are lack in considering the dynamic and unpredictable event handling. In this paper, we propose a representative environmental model in representation of emergency and dynamic resource allocation model, and an adaptive mathematical model based on Genetic Algorithm (GA) to generate an optimal set More >

Wen Zhao, Dongxing Mao^*, Zaixiu Jiang

Sound & Vibration, Vol.53, No.1, pp. 37-46, 2019, DOI:10.32604/sv.2019.04368

Abstract In order to analyze the effect of the background flow on the sound prediction of fine-scale turbulence noise, the sound spectra from static and flow environments are compared. It turns out that, the two methods can obtain similar predictions not only at 90 deg to the jet axis but also at mid- and high frequencies in other directions. The discrepancies of predictions from the two environments show that the effect of the jet flow on the sound propagation is related to low frequencies in the downstream and upstream directions. It is noted that there is More >

Lei Chu, H. M. K. Darshika Hennayake, Haijun Sun*

Phyton-International Journal of Experimental Botany, Vol.88, No.3, pp. 261-267, 2019, DOI:10.32604/phyton.2019.07791

Abstract Intensive practices in forest soils result in dramatic nitrogen (N) losses, particularly ammonia (NH₃) volatilization, to adjacent environmental areas. A soil column experiment was conducted to evaluate the effect of bamboo biochar on NH₃ volatilization from tea garden and bamboo forest soils. The results showed that biochar amendment effectively reduced NH₃ volatilization from tea garden and bamboo forest soil by 79.2% and 75.5%, respectively. The soil pH values increased by 0.53-0.61 units after biochar application. The NH₄⁺-N and total N of both soils were 13.8-29.7% and 34.0-41.9% higher under the biochar treatments than under the control treatment, More >