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  • Open Access

    ARTICLE

    Location and Object Aware Model for Parallel Activity Recognition in Multi-Resident Smart Homes

    Hafiz Safdar Sultan1, Labiba Gillani Fahad1, Noshina Tariq2, Noor Zaman Jahnjhi3,4, Mamoona Humayun5,*

    CMC-Computers, Materials & Continua, Vol.87, No.3, 2026, DOI:10.32604/cmc.2026.076379 - 09 April 2026

    Abstract Smart homes enable elderly individuals and people with impairments to live independently through remote monitoring of their activities. Sequences of sensor activations are mapped with their associated labels to recognize different activities. Activity recognition in a multi-resident environment is challenging due to multiple activities performed by different residents in parallel. A novel multi-resident activity recognition approach is proposed to separate the sensor events based on their location. A spatial matrix is generated to capture the spatial and temporal patterns of the activities, and activations of sensors are recorded as binary values. The spatial matrix is More >

  • Open Access

    ARTICLE

    The Influence of Temperature Environment and Polymeric Binder Proportion on the Static/Dynamic Mechanical Properties of Polymer Materials

    Peng Gong1, Tingzheng Yan1, Kang Yang2, Yumei Yue2,*, Shude Ji2,*, Lin Ma3, Yilun Wu1

    Journal of Polymer Materials, Vol.43, No.1, 2026, DOI:10.32604/jpm.2025.074794 - 03 April 2026

    Abstract To comprehensively explore the impact of binder content on the mechanical properties of the Polymer bonded explosive (PBX) substitute material (Polymer-bonded Analogue Explosive (PAE)—it is renowned for its outstanding high-temperature resistance, exceptional mechanical properties, excellent chemical stability, and superior electrical insulation), a series of experiments are meticulously carried out. The dynamic and static mechanical properties, along with the microstructure of PAE, are precisely measured through the Split Hopkinson Pressure Bar (SHPB) test, static compression tests, and Scanning Electron Microscopy (SEM). The dynamic performance test outcomes clearly indicate that both the binder content (2%, 4%, 6%)… More >

  • Open Access

    ARTICLE

    Deep Learning-Based Structural Displacement Identification and Quantification under Target Feature Loss

    Lishuai Zhu1, Guangcai Zhang1,*, Qun Xie1,*, Zhen Peng2, Li Ai3, Ruijun Liang1, Taochun Yang1

    Structural Durability & Health Monitoring, Vol.20, No.2, 2026, DOI:10.32604/sdhm.2025.074620 - 31 March 2026

    Abstract Structural displacement monitoring faces significant challenges under complex environmental conditions due to the loss or degradation of target features, making it difficult for traditional methods to ensure high accuracy and robustness. Therefore, this study proposes a structural displacement identification and quantification method that integrates YOLOv8n with an improved edge-orientation gradient-based template matching algorithm. By combining deep learning techniques with traditional template matching methods, the accuracy and robustness of monitoring are enhanced under adverse conditions such as noise and extremely low illumination. Specifically, in the edge-orientation gradient matching stage, the Canny-Devernay sub-pixel edge detection technique and… More >

  • Open Access

    EDITORIAL

    Advances in Integrated Energy–Water–Environment Systems and Energy Storage Systems

    Antun Pfeifer1,*, Dongran Song2, Mohamed Talaat Moustafa3, Neven Duić1,4

    Energy Engineering, Vol.123, No.4, 2026, DOI:10.32604/ee.2026.079714 - 27 March 2026

    Abstract The energy transition increasingly requires holistic approaches that integrate electricity, heating and cooling, water management, industrial processes, transport, and environmental considerations within coherent system frameworks. Such integration is essential for achieving deep decarbonisation while maintaining reliability, affordability, and resource efficiency across diverse regional and sectoral contexts. This Special Issue of Energy Engineering presents selected contributions from the 2024 Conferences on Sustainable Development of Energy, Water and Environment Systems (SDEWES), reflecting recent advances in modelling, system integration, and technology deployment. The included papers address a broad spectrum of challenges relevant to integrated energy–water–environment systems. These include building-sector… More >

  • Open Access

    ARTICLE

    Potential of Quebracho Tannin to Substitute Urea-Formaldehyde Adhesive in Plywood: Comparative Technical and Environmental Performance

    Belén Rovira1,*, Aude Chabrelie1, Sauro Bianchi2, Frédéric Pichelin1

    Journal of Renewable Materials, Vol.14, No.3, 2026, DOI:10.32604/jrm.2025.02025-0173 - 25 March 2026

    Abstract The construction sector is facing significant challenges in transitioning to a defossilised system. While wood-based products have considerable potential, reliance on adhesives derived from fossil fuels poses significant sustainability concerns. Tannin-based adhesives present a compelling bio-based alternative, offering advantageous bonding properties with the potential to reduce toxicity, minimise fossil resource use, and enhance end-of-life scenarios. Despite extensive research demonstrating the technical potential of tannin-based adhesives, industrial adoption remains limited—partly due to the paucity of studies addressing their environmental impacts. The present study investigates the use of tannin-based adhesives in the production of interior-grade plywood, employing… More >

  • Open Access

    REVIEW

    Bacterial Biorefineries: Transforming Agro-Industrial Waste into Sustainable Solutions for a Circular Bioeconomy

    Sevakumaran Vigneswari1,2,*, Muhammad Shahrul Md Noor3, Fazilah Ariffin3,4, Azila Adnan3,4, Amirah Alias3, Lakshmanan Muthulakshmi5, Hemalatha Murugaiah6, Nor Omaima Harun3,4, Nurul Nadhirah Ruzelan3, Lakshiminarayanan Rajamani2

    Journal of Renewable Materials, Vol.14, No.3, 2026, DOI:10.32604/jrm.2025.02025-0148 - 25 March 2026

    Abstract The escalating accumulation of agro-industrial waste—exceeding 350 million tons annually from post-harvest residues, food processing, and aquaculture—poses serious environmental threats, including greenhouse gas emissions, groundwater contamination, and excessive landfill usage. Although conventional treatment methods such as composting, incineration, and recycling offer partial mitigation, they often fall short of delivering scalable, circular solutions. Microbial biorefineries have emerged as a transformative approach, enabling the conversion of diverse biomass streams into high-value renewable materials. Through microbial fermentation, agricultural and municipal waste can be repurposed into functional outputs such as nanocellulose, biochar, and biocompatible compounds with applications in packaging, More > Graphic Abstract

    Bacterial Biorefineries: Transforming Agro-Industrial Waste into Sustainable Solutions for a Circular Bioeconomy

  • Open Access

    REVIEW

    HBx Protein in Hepatitis B Virus-Related Hepatocellular Carcinoma: Pathogenic Mechanisms and Emerging Interventions

    Chung-Che Tsai1,#, Chih-Hung Lin2,#, Katherine Lin3,4, Jia Hong Hubert Chen4,5, Ying Jie Celia Chen4,5, Ilyssa Ting-Ying Chang3,4, Hsu-Hung Chang6, Jin-Yin Chang7, Tin-Yi Chu8, Po-Chih Hsu4,8,*, Chan-Yen Kuo8,*

    BIOCELL, Vol.50, No.3, 2026, DOI:10.32604/biocell.2025.073698 - 23 March 2026

    Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, most commonly driven by chronic hepatitis B virus (HBV) infection. The HBV X protein (HBx) plays a central role in hepatocarcinogenesis by regulating transcription, signal transduction, epigenetic modification, and interactions with noncoding RNAs. This review summarizes current advances in HBx-mediated signaling pathways and mutation-specific functions, highlighting its potential as a prognostic biomarker and therapeutic target, and providing insights for future strategies in HCC treatment and HBV eradication. Activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), cAMP response element binding protein/activating transcription factor More > Graphic Abstract

    HBx Protein in Hepatitis B Virus-Related Hepatocellular Carcinoma: Pathogenic Mechanisms and Emerging Interventions

  • Open Access

    REVIEW

    Exploring the Latest Developments in Natural Killer (NK) Cell-Based Therapies for Diffuse Intrinsic Pontine Glioma (DIPG)

    Kawaljit Kaur*

    BIOCELL, Vol.50, No.3, 2026, DOI:10.32604/biocell.2025.073340 - 23 March 2026

    Abstract Diffuse intrinsic pontine glioma (DIPG) is a pediatric brainstem tumor with a very poor prognosis, characterized by immunosuppressive tumor microenvironment (TME) that limits immune infiltration, including a significant reduction in circulating natural killer (NK) cells. This drop in NK cell levels and activity may promote tumor growth and immune evasion, making NK cells a promising target for immunotherapy. NK cells can attack and eliminate DIPG tumor cells, including glioma stem cells, while counteracting certain immune evasion strategies. Although the DIPG microenvironment and blood-brain barrier present challenges, NK cell-based therapies have shown encouraging tumor control and… More >

  • Open Access

    REVIEW

    Advances in Metabolic Reprogramming and Immune Regulatory Mechanisms in Lung Cancer

    Xiaomeng Li1,2, Xuejiao Li2, Hongbo Wu1,*, Rui Li1,*

    Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2026.076176 - 23 March 2026

    Abstract Lung cancer remains the leading cause of cancer-related mortality worldwide, primarily driven by metabolic reprogramming and immune evasion mechanisms within tumor cells. To adapt to the nutrient-deprived tumor microenvironment (TME), lung cancer cells undergo profound metabolic reprogramming, characterized by enhanced glycolysis (the Warburg effect), increased glutamine dependency (mediated by GLS1), and accelerated lipid synthesis (involving enzymes such as FASN). These metabolic alterations not only remodel the TME but also dampen antitumor immune responses by promoting immunosuppressive cell populations (e.g., Tregs and M2 macrophages) and inhibiting effector functions of CD8+ T cells and natural killer (NK) cells.… More >

  • Open Access

    REVIEW

    Understanding the Tumor Microenvironmental Mechanisms Driving Immunotherapy Resistance in Colorectal Cancer Liver Metastases

    Candela Cives-Losada1,2, Cristiana Soldani2, Michela Anna Polidoro2, Barbara Franceschini2, Ana Lleo3,4, Marcello Di Martino1,5, Matteo Donadon1,5,*

    Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2025.074093 - 23 March 2026

    Abstract Colorectal cancer (CRC) is the second deadliest cancer worldwide, being the presence of metastasis, mainly in the liver, a major contributor to high mortality rates in affected patients. The tumor microenvironment (TME)—comprised of interacting endothelial, stromal, and immune cells—plays a critical role in creating a supportive niche for tumor cell colonization and immune evasion and, thus, the establishment of metastases. The liver’s intrinsic nature further facilitates the development of immune tolerance, mediated by regulatory T cells, myeloid-derived suppressor cells, and soluble factors such as anti-inflammatory cytokines, which together dampen antitumor immune responses. This immunosuppressive milieu More > Graphic Abstract

    Understanding the Tumor Microenvironmental Mechanisms Driving Immunotherapy Resistance in Colorectal Cancer Liver Metastases

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