Daiki Nobayashi^1,*, Meiya Tanaka², Naoki Tanaka², Riku Nakamura², Kazuya Tsukamoto³, Takeshi Ikenaga¹, Shu Sekigawa⁴, Myung Lee⁵

CMC-Computers, Materials & Continua, Vol.87, No.3, 2026, DOI:10.32604/cmc.2026.077008 - 09 April 2026

Abstract To realize local production and consumption of Spatio-temporal data (STD), it is essential to address two key challenges: (1) maintaining data locality by retaining and distributing STD close to their generation area, and (2) enabling application execution on heterogeneous and resource-constrained devices through a lightweight and portable execution platform. To address these challenges, we developed a Floating Cyber-Physical System (F-CPS) that retains both STD and the functions required to process and use the STD within a specific area. In the F-CPS, the STD Retention System directly distributes STD from the generation location and maintains the… More >

Giada Faraco^*, Andrea Vincenzo De Nunzio, Nicola Ivan Giannoccaro^*, Arcangelo Messina

Structural Durability & Health Monitoring, Vol.20, No.2, 2026, DOI:10.32604/sdhm.2025.075327 - 31 March 2026

Abstract Damage detection and localization analysis have gained increasing importance over the years, due to the growing number of catastrophic events and the associated risks that small, undetected cracks in structures may evolve into severe failures if not identified in time. In this context, vibration-based methods have been extensively investigated for structural damage detection. Among them, one of the most widely used approaches since its introduction is the curvature method. It has been successfully employed in numerous studies, consistently providing reliable results. However, the use of second-order or higher-order derivatives can be challenging when dealing with… More >

Ana Luisa Arantes Chaves^1,*, Marco Tulio Mendes Ferreira²

Phyton-International Journal of Experimental Botany, Vol.95, No.3, 2026, DOI:10.32604/phyton.2026.077185 - 31 March 2026

Abstract Holocentric chromosomes, characterized by kinetochore activity distributed along almost their entire length, have attracted growing interest in cytogenetics and evolutionary biology, particularly because of their adaptive significance. This review provides a historical overview of research on holocentricity, from the earliest microscopic observations to recent advances made possible by modern molecular and cytogenetic techniques. We discuss the main hypotheses concerning the origin and evolution of holocentric chromosomes, emphasizing their multiple independent origins across diverse lineages, as well as the potential selective pressures underlying their maintenance and diversification. In addition, we examine the principal methods used for More >

Eshita Dhar^1,2, Muhammad Ashad Kabir³, Divyabharathy Ramesh Nadar⁴, Li-Jen Kuo⁵, Jitendra Jonnagaddala^6,7, Yaoru Huang¹, Mohy Uddin^8,*, Shabbir Syed-Abdul^1,2,9,*

Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2026.074385 - 23 March 2026

Abstract Objectives: Decisions regarding CT after nCCRT for locally advanced rectal cancer (LARC) are challenging due to limited evidence guiding treatment. This study aimed to (i) evaluate the predictive performance of machine learning (ML) models in patients treated with neoadjuvant concurrent chemoradiotherapy (nCCRT) alone vs. those receiving nCCRT plus chemotherapy (CT), (ii) identify features associated with treatment improvement, and (iii) derive ML-based thresholds for treatment response. Methods: This retrospective study included 409 patients with LARC treated at three affiliated hospitals of Taipei Medical University. Patients were categorised into two groups: nCCRT alone followed by surgery (n =… More >

Vincenzo Montanarella¹, Marcelo Guerrero^2,3, David Filho^2,3, Júlia German-Cortés¹, Giacomoluciano Vitelli¹, Magalí Sureda¹, Carlos Pavón Regaña¹, Roser Ferrer^1,4, Simó Schwartz^1,4, Esteban Durán-Lara^2,3, Fernanda Andrade^1,5,*, Diana Rafael^1,6,*

Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2026.074061 - 23 March 2026

Abstract Despite remarkable advances in nanomedicine, localized delivery of advanced cancer therapeutics remains underexploited. Advanced therapies based on biopharmaceuticals, immunotherapy, or gene therapy have revolutionized oncology. Yet, their systemic administration is often associated with limitations such as poor site-specific accumulation, instability, and systemic toxicity. Hydrogels/macrogels offer the ability to encapsulate, protect, and release biomolecules in situ with sustained and stimulus-responsive profiles, addressing key translational gaps. This review provides a focused synthesis of the last five years of hydrogel-based research for cancer therapy, with emphasis on peptides, antibodies, immunotherapeutic agents, and gene delivery systems. We discuss design principles,… More > Graphic Abstract

Thi-Loan Nguyen^1,2,*, Huy-Nam Chu³, The-Thanh Hua³, Trung-Nghia Phung², Van-Hung Le^3,*

CMC-Computers, Materials & Continua, Vol.87, No.2, 2026, DOI:10.32604/cmc.2026.076732 - 12 March 2026

Abstract To support the process of grasping objects on a tabletop for the blind or robotic arm, it is necessary to address fundamental computer vision tasks, such as detecting, recognizing, and locating objects in space, and determining the position of the grasping information. These results can then be used to guide the visually impaired or to execute grasping tasks with a robotic arm. In this paper, we collected, annotated, and published the benchmark TQU-GraspingObject dataset for testing, validation, and evaluation of deep learning (DL) models for detecting, recognizing, and localizing grasping objects in 2D and 3D… More >

Zhengyu Wu¹, Kejun Kang², Yixiu Liu^3,*, Chenpu Li³

CMC-Computers, Materials & Continua, Vol.87, No.2, 2026, DOI:10.32604/cmc.2026.075593 - 12 March 2026

Abstract Binary segmentation tasks in computer vision exhibit diverse appearance distributions and complex boundary characteristics. To address the limited generalization and adaptability of existing models across heterogeneous tasks, we propose Abel-Net, an Aggregated Bilateral Edge Localization Network designed as a universal framework for multi-task binary segmentation. Abel-Net integrates global and local contextual cues to enhance feature learning and edge precision. Specifically, a multi-scale feature pyramid fusion strategy is implemented via an Aggregated Skip Connection (ASC) module to strengthen feature adaptability, while the Edge Dual Localization (EDL) mechanism performs coarse-to-fine refinement through edge-aware supervision. Additionally, Edge Attention More >

Wenchao Shi¹, Tao Wei², Chuan Yang³, Qichao Fan³, Hongxi Liu⁴, Bin Shao^5,*, Peng Jing^4,*

CMC-Computers, Materials & Continua, Vol.87, No.2, 2026, DOI:10.32604/cmc.2026.075293 - 12 March 2026

Abstract Enhancing the strength of nanotwinned aluminum (Al) is essential for the development of next-generation high-end chip technology. To better understand the detwinning behavior of nanotwinned Al under conditions with no resolved shear stress acting on the twin boundaries, we conducted molecular dynamics simulations of uniaxial tensile deformation in nanotwinned single-crystal Al at room temperature. Detwinning is observed only when the twin boundary spacing is 7.01 Å. At larger spacings, twin boundaries remain parallel to the loading direction, with no rotation or bending, indicating negligible migration. Detwinning is triggered by localized stress from dislocation interactions, with More >

Gilberto Chéchile Toniolo¹, Nuria Jornet^1,*, Jady Rojas¹, Natalia Tejedor¹, Santiago Carrara¹, Alicia Maccagno², Teresa Brufau¹

Canadian Journal of Urology, Vol.33, No.1, pp. 93-103, 2026, DOI:10.32604/cju.2026.069182 - 28 February 2026

Abstract Background: Low-dose rate (LDR) prostate brachytherapy is a recommended treatment of localized prostate cancer in current guidelines. The study aimed to determine biochemical relapse-free survival (BRFS) in patients treated with dynamic real-time low-dose rate (LDR) brachytherapy using Iodine 125 (I¹²⁵). Methods: We retrospectively reviewed 499 patients with localized prostate cancer treated with I¹²⁵ LDR real-time brachytherapy between 2003 and 2021. The mean patient age was 65 years (range: 45–84 years). Based on the National Comprehensive Cancer Network (NCCN) risk classification, 230 patients (46.1%) were categorized as low risk, 235 (47.1%) as intermediate risk, and 34 (6.8%)… More >

Jonathon Carll^1,2,3,*, Jacinta Bonaddio¹, Dixon Woon^1,4,5, Marlon Perera^1,4,5,6, Nathan Lawrentschuk^2,3,5,6, Thilakavathi Chengodu^1,3

Canadian Journal of Urology, Vol.33, No.1, pp. 21-34, 2026, DOI:10.32604/cju.2025.068908 - 28 February 2026

Abstract Prostate-specific membrane antigen (PSMA) is a surface membrane antigen that is highly overexpressed in prostate cancer, with heterogenous expression throughout the natural history of the disease. This has generated significant interest as a potential biomarker for use in early diagnosis and treatment of prostate cancer. We reviewed the literature surrounding PSMA and its current clinical applications in diagnosing and managing early prostate cancer that is confined to the prostate and local lymph nodes. A search on PubMed, Medline, and Web of Science was performed using the following keywords: “PSMA”, “Prostate Specific Membrane Antigen”, “Prostate cancer”,… More >