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  • Open Access

    ARTICLE

    Geometric Confinement Influences Cellular Mechanical Properties I -- Adhesion Area Dependence

    Judith Su, Xingyu Jiang, Roy Welsch, George M. Whitesides§, Peter T. C. So

    Molecular & Cellular Biomechanics, Vol.4, No.2, pp. 87-104, 2007, DOI:10.3970/mcb.2007.004.087

    Abstract Interactions between the cell and the extracellular matrix regulate a variety of cellular properties and functions, including cellular rheology. In the present study of cellular adhesion, area was controlled by confining NIH 3T3 fibroblast cells to circular micropatterned islands of defined size. The shear moduli of cells adhering to islands of well defined geometry, as measured by magnetic microrheometry, was found to have a significantly lower variance than those of cells allowed to spread on unpatterned surfaces. We observe that the area of cellular adhesion influences shear modulus. Rheological measurements further indicate that cellular shear… More >

  • Open Access

    ARTICLE

    Mechanical Properties of Carbon Nanotubes Using Molecular Dynamics Simulations with the Inlayer van der Waals Interactions

    W.H. Chen1, H.C. Cheng2, Y.C. Hsu3

    CMES-Computer Modeling in Engineering & Sciences, Vol.20, No.2, pp. 123-146, 2007, DOI:10.3970/cmes.2007.020.123

    Abstract The evaluation of the fundamental mechanical properties of single/multi-walled carbon nanotubes(S/MWCNTs) is of great importance for their industrial applications. The present work is thus devoted to the determination of various mechanical properties of S/MWCNTs using molecular dynamics (MD) simulations. The study first focuses on the exploration of the effect of the weak inlayer van der Waals (vdW) atomistic interactions on the mechanical properties of S/MWCNTs. Secondly, in addition to the zig-zag and armchair types of CNTs, the hybrid type of MWCNTs that comprise a zig-zag outer tube and an inner armchair tube is also analyzed.… More >

  • Open Access

    ARTICLE

    Nanomechanical Properties of Electrospun PLGA Nanofibers

    X. Xin1, M. Hussain1, J. Mao1

    Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 187-188, 2006, DOI:10.32604/mcb.2006.003.187

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    The Effect of Processing Temperature on Mechanical Properties of Novel Silk Fibroin and Chitosan Blend Scaffolds for Musculoskeletal Regeneration

    C. N. Rios1, J. N. Augustine1, A. B. Mathur1

    Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 173-174, 2006, DOI:10.32604/mcb.2006.003.173

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Finite Element modeling of Nomex® honeycomb cores : Failure and effective elastic properties

    L. Gornet1, S. Marguet2, G. Marckmann3

    CMC-Computers, Materials & Continua, Vol.4, No.2, pp. 63-74, 2006, DOI:10.3970/cmc.2006.004.063

    Abstract The purpose of the present study is to determine the components of the effective elasticity tensor and the failure properties of Nomex® honeycomb cores. In order to carry out this study, the NidaCore software, a program dedicated to Nomex®Cores predictions, has been developed using the Finite Element tool Cast3M-CEA. This software is based on periodic homogenization techniques and on the modelling of structural instability phenomena. The homogenization of the periodic microstructure is realized thanks to a strain energy approach. It assumes the mechanical equivalence between the microstructures of a RVE and a similar homogeneous macroscopic volume.… More >

  • Open Access

    ARTICLE

    A New Fast Multipole Boundary Element Method for Large Scale Analysis of Mechanical Properties in 3D Particle-Reinforced Composites

    Haitao Wang1, Zhenhan Yao1

    CMES-Computer Modeling in Engineering & Sciences, Vol.7, No.1, pp. 85-96, 2005, DOI:10.3970/cmes.2005.007.085

    Abstract This paper addresses a new boundary element method (BEM) for the numerical analysis of mechanical properties in 3D particle-reinforced composites. The BEM is accelerated by a new version fast multipole method (FMM) in order to perform large scale simulation of a representative volume element (RVE) containing up to several hundred randomly distributed elastic spherical particles on only one personal computer. The maximum number of degrees of freedom (DOF) reaches more than 300,000. Efficiency of the developed new version fast multipole BEM code is evaluated compared with other conventional solutions for BEM. The effects of micro-structural More >

  • Open Access

    ARTICLE

    Estimation of the Mechanical Properties of Amorphous Metal with a Dispersed Nano-crystalline Particle by Molecular Dynamics Simulation

    R. Matsumoto, M. Nakagaki

    CMES-Computer Modeling in Engineering & Sciences, Vol.10, No.3, pp. 187-198, 2005, DOI:10.3970/cmes.2005.010.187

    Abstract Large-scale molecular dynamics simulations of tensile deformation of amorphous metals containing a nano-crystalline particle were performed in order to clarify the effects of particle size and crystal volume fraction on the deformation mechanism and strength. It became clear that particle size has very little effect, while crystal volume fraction has a substantial influence. Elastic modulus and flow stress intensify as crystal volume fraction increases. Furthermore, the stress in the crystal phase continues to increase, even after yielding in the amorphous phase. Consequently, work-hardening effects appear, preventing localization of plastic deformation. Thus, the dispersed nano-crystalline particles… More >

  • Open Access

    ARTICLE

    Bone and Joints Modelling with Individualized Geometric and Mechanical Properties Derived from Medical Images

    M.C. Ho Ba Tho1

    CMES-Computer Modeling in Engineering & Sciences, Vol.4, No.3&4, pp. 489-496, 2003, DOI:10.3970/cmes.2003.004.489

    Abstract The objective of the paper is to address the methodology developed to model bone and joints with individualised geometric and material properties from medical image data. An atlas of mechanical properties of human bone has been investigated demonstrating individual differences. From these data, predictive relationships have been established between mechanical properties and quantitative data derived from measurements on medical images. Subsequently, geometric and numerical models of bones with individualised geometrical and mechanical properties have been developed from the same source of image data. The advantages of this modelling technique are its ability to study the More >

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