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  • Open Access

    REVIEW

    Melatonin and its protective role against male reproductive toxicity induced by heavy metals, environmental pollutants, and chemotherapy: A review

    TIECHENG SUN1,#, LINGLI SONG1,#, JING MA2,#, HONG YU1, SHANJIE ZHOU1, SHUSONG WANG2, LI TIAN1,3,*

    BIOCELL, Vol.44, No.4, pp. 479-485, 2020, DOI:10.32604/biocell.2020.011675 - 24 December 2020

    Abstract Melatonin, as a ubiquitous indoleamine hormone, is synthesized primarily by the pineal gland. It has diverse biological effects through quite complex mechanisms. More recently, studies have focused on the mechanism of melatonin in anti-reproductive toxicity/damage. Since melatonin possesses strong antioxidant and anti-apoptotic properties, researchers have examined its potential role in protecting against male reproductive toxicity/damage, which may be induced by chemotherapy or environmental toxicants and can lead to male infertility. In this article, recent progress regarding the protective effects of melatonin on male reproductive toxicity/damage is reviewed. More >

  • Open Access

    ARTICLE

    Effects of Melatonin on Growth, Physiology and Gene Expression in Rice Seedlings Under Cadmium Stress

    Xiachen Lv1,#, Yunxia Fang1,#, Lantian Zhang1, Weiyi Zhang1, Ling Xu1, Jingjin Han1, Bailing Jin2, Xian Zhang1, Xiaoqin Zhang1,*, Dawei Xue1,*

    Phyton-International Journal of Experimental Botany, Vol.88, No.2, pp. 91-100, 2019, DOI:10.32604/phyton.2019.06622

    Abstract Melatonin (MLT) is a hormonal substance found in many organisms and can improve plant stress resistance. In this study, the japonica rice variety Y32 and indica rice variety NJ6 were cultivated in hydroponics under different concentrations of CdCl2 at the two-leaf stage. The growth, physiological and biochemical responses of the seedlings and the expression of cadmium (Cd)-related genes under exogenous melatonin (MLT) treatment were assessed. The results indicated that Cd stress destroyed the dynamic balance between reactive oxygen species (ROS) production and removal, resulting in ROS accumulation, membrane lipid peroxidation, and impaired growth and development. Following the… More >

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