T. C. Theoharides^1,2,3, D. Kempuraj¹, S. Vakali¹, G. R. Sant⁴

Canadian Journal of Urology, Vol.15, No.6, pp. 4410-4414, 2008

Abstract Objectives: Interstitial cystitis/Painful bladder syndrome (IC/PBS) is a chronic bladder condition of unknown etiology and pathogenesis. However, there is evidence of bladder surface mucosal and glycosaminoglycans (GAG) dysfunction in IC/PBS and GAG replacement therapy has been used to treat the condition. The results of an open label, uncontrolled study of a dietary supplement designed to improve GAG mucopolysaccharides integrity (glucosamine sulfate, sodium hyaluronate and chondroitin sulfate) and reduce bladder wall inflammation (quercetin, rutin) are presented herein.
Methods: Two hundred fifty two IC/PBS patients (25 men, 227 women; 18-69 years old), who had failed other treatments, took four… More >

Lori M. Dulabon¹, Amar Singh¹, Frank Vogel², Alireza Moinzadeh¹

Canadian Journal of Urology, Vol.14, No.3, pp. 3588-3591, 2007

Abstract We report a case of a 19-year-old female who presented with right flank pain and microscopic hematuria.Three years earlier, she sustained a stab wound to the right flank and was managed conservatively. After being diagnosed with an enhancing renal mass using computed tomography (CT) scan, duplex ultrasound and angiography were performed revealing an intrarenal pseudoaneurysm. Endovascular coils were successfully employed to selectively embolize the pseudoaneurysm. More >

Joel M. H. Teichman¹, Robert Moldwin²

Canadian Journal of Urology, Vol.14, No.4, pp. 3599-3607, 2007

Abstract Introduction: Interstitial cystitis (IC) is a potentially severe and debilitating condition of the bladder. Numerous factors have been implicated in its pathogenesis.
Materials and methods: A literature review was conducted on the following topics: urothelium, mucosal lining, interstitial cystitis, bladder, and glycosaminoglycans.
Results: A commonly proposed cause for IC is a defect or alteration in the bladder surface leading to increased permeability to noxious urinary solutes and ultimately to tissue inflammation and neurogenic upregulation. Support for this concept is drawn from studies of the structure, function, and composition of the bladder surface. The cause(s) of this alteration More >

Khurshid A. Guru^1,4, Gregory E. Wilding^3,6, Pamela Piacente¹, Jannah Thompson⁴, Wei Deng⁶, Hyung L. Kim^1,4, James Mohler^1,4, Kathleen O’Leary^2,5

Canadian Journal of Urology, Vol.14, No.6, pp. 3753-3756, 2007

Abstract Introduction: To date, no study has compared postoperative pain and requirement for pain medications in open versus robot-assisted radical cystectomy. Patient reported pain and opiate use were reviewed retrospectively using prospectively collected data from postoperative day one to day of discharge.
Materials and methods: Twenty consecutive robot-assisted radical cystectomy patients were compared to the prior 20 patients who underwent open radical cystectomy. Data was collected prospectively to determine opiate requirements and pain scores in each group. Daily opiate use was converted to morphine sulfate equivalents (MSE) to facilitate comparison. A Likert pain perception scale was used to… More >

Serrano-Bernardo F¹, JL Rosúa¹, M Díaz-Miguel²

Phyton-International Journal of Experimental Botany, Vol.76, pp. 27-38, 2007, DOI:10.32604/phyton.2007.76.027

Abstract The Mediterranean region is considered one of the most important zones worldwide in terms of plant diversity. Sierra Nevada (S Spain) is a unique mountain massif within the high-mountain systems of the Mediterranean. It is of great floristic importance and very rich in endemic species. However, it requires numerous tasks for restoring plant cover due to the constant anthropic degradation, especially because of the ski station located near the second-highest peak of the mountain. One of the restoration efforts consists of trying to reproduce, in the laboratory, the ideal conditions to pre-germinate seeds of some… More >

M.T. MARTIN^*, H.E. PEDRANZANI^**, R. SIERRA DE GRADO

BIOCELL, Vol.31, No.1, pp. 41-49, 2007, DOI:10.32604/biocell.2007.31.041

Abstract An in vitro collection has been established with selected European aspen from Palencia province (Spain). Currently, this collection includes 32 high quality clones, selected for their good bearing and healthy state. Most of them belong to different discrete local populations.
Populus tremula L. was propagated in proliferation Aspen Culture Medium; they required subculture every 3 months. The purpose of this study was, therefore, to select a medium which allows the maintenance of 32 clones for a period longer than 3 months without subculture and to observe the behavior of those clones in 15 different culture medium compositions. Seven… More >

F. Dunet¹, Ch. Pfister¹, M. Deghmani², Y. Meunier², G. Demeilliers-Pfister², Ph. Grise¹

Canadian Journal of Urology, Vol.11, No.2, pp. 2200-2204, 2004

Abstract Objectives: Improvement of radical prostatectomy surgical technique remains an objective for urological practice. The aim of this study was to evaluate the potential benefit of intra and postoperative epidural versus general anesthesia alone.
Material and methods: The authors retrospectively analyzed 62 consecutive cases of patients who underwent radical retropubic prostatectomy over a 2-year period. The mean age was 65.5 years (51-75). Two groups were selected: group I = 19 patients, who received epidural anesthesia in association with general anesthesia and group II = 43 patients with general anesthesia alone. Both groups were similar for ASA score, Body… More >

Iliana C. Lega, Gerald B. Brock, Patrick P. W. Luke

Canadian Journal of Urology, Vol.11, No.6, pp. 2459-2460, 2004

Abstract Despite excellent overall results, some patients continue to experience flank pain post-pyeloplasty. For the first time, we report the successful use of laparoscopically-assisted renal autotransplantation in the treatment of refractory flank pain post-pyeloplasty. More >

Victor H. Hartanto, David DiPiazza, Murali K. Ankem, Carmen Baccarini, Nancy J. Lobby

Canadian Journal of Urology, Vol.10, No.1, pp. 1759-1763, 2003

Abstract Materials and methods: A total of 64 women (mean age = 57) were treated for stress urinary incontinence secondary to intrinsic sphincter deficiency or hypermobility between March 1998 to August 2000. Group I (SPWS) consisted of 30 patients who underwent in situ vaginal wall sling with suprapubic placement of bone anchors in the pubic tubercle utilizing the Vesica system. Group II (TVCS) consisted of 34 patients who underwent cadaveric fascia sling with transvaginal placement of bone anchors behind the symphysis pubis utilizing the Precision-TAC system. Phone interviews were conducted by a third party who was blinded… More >

Fred Saad, Robert Sabbagh, Michael McCormack, François Peloquin

Canadian Journal of Urology, Vol.9, No.4, pp. 1592-1594, 2002

Abstract Purpose: To compare patient reported pain during TRUS guided biopsies using intrarectal lidocaine gel versus lubricating gel.
Materials and methods: From May 2000 to May 2001, 360 men undergoing transrectal prostate biopsy were enrolled in this study. Patients were randomized into two groups. In group 1, 180 patients received 10 cc of 2% intrarectal lidocaine gel (Xylocaine® 2% jelly, Astra Pharma Inc.) 5 to 10 minutes before the procedure and in group 2, 180 patients received 10 cc of lubricating gel. No other sedation or analgesia was given. Pain level immediately after the last biopsy was assessed More >