Robert J. Evans¹, Tyler Overholt¹, Marc Colaco¹, Stephen J. Walker^1,2

Canadian Journal of Urology, Vol.27, No.1, pp. 10125-10129, 2020

Abstract Introduction: Botulinum toxin A (BTX-A) is currently used as a fourth-line therapeutic option for interstitial cystitis/bladder pain syndrome (IC/BPS) management. The purpose of this study was to determine if BTX-A injection can mitigate pain and if injection location (i.e., trigone-including versus trigone-sparing injection template) impacts treatment efficacy and/or treatment complications profile.
Materials and methods: Female IC/BPS patients refractory to conservative management strategies were prospectively enrolled and asked to complete a baseline history and physical exam, post-void residual (PVR) urine volume determination, O’Leary Sant (OLS) questionnaire, and Pelvic Pain and Urgency/Frequency Symptom Scale (PUF) questionnaire. Participants were randomly… More >

Tyler L. Overholt¹, Robert J. Evans¹, Bruce A. Lessey³, Catherine A. Matthews¹, Katherine N. Hines¹, Gopal Badlani¹, Stephen J. Walker^1,2

Canadian Journal of Urology, Vol.27, No.3, pp. 10257-10262, 2020

Abstract Introduction: Interstitial cystitis/bladder pain syndrome (IC/BPS) and endometriosis are coexistent diagnoses in 48%-65% of women with chronic pelvic pain (CPP), suggesting that dual screening may be warranted. To further investigate the clinical relationship and risk factors between these two conditions, we performed a retrospective review of our large IC/BPS patient data registry.
Materials and methods: We evaluated IC/BPS patients who were prospectively enrolled into our registry who completed validated questionnaires and underwent therapeutic hydrodistension, during which anesthetic bladder capacity (BC) and Hunner’s lesion (HL) status were recorded. Demographic/medical history were reviewed. IC/BPS patients with co-occurring endometriosis diagnosis… More >

Thenappan Chandrasekar^1,*, Lydia Glick², Daniella Wong², Timothy M. Han², Joon Yau Leong², Misung Yi³, James R. Mark¹, Mark J. Mann¹, Edouard J. Trabulsi¹, Costas D. Lallas¹

Canadian Journal of Urology, Vol.27, No.3, pp. 10250-10256, 2020

Abstract Introduction: To evaluate the impact of an “opt-in” non-narcotic postoperative pain regimen on narcotic utilization and patient-reported pain scores.
Materials and methods: A prospective, non-blinded pre- and post-interventional trial was conducted, including a lead-in period for baseline evaluation. The intervention group received a new pain protocol prioritizing non-narcotic medications, an “opt-in” requirement for opiates, and standardized patient education. Study outcomes included opiate prescription and utilization (measured in Morphine Equivalent Doses) and reported pain scores on postoperative day (POD) 1, discharge, and follow-up.
Results: At discharge, 70% fewer patients were prescribed any opioids (ARR: -0.7; p < 0.001); the… More >

Andrew Stamm, Basil Ferenczi, Christopher Porter, Paul Kozlowski, Ryan Donahue, John Corman

Canadian Journal of Urology, Vol.27, No.5, pp. 10363-10368, 2020

Abstract Introduction: Continence and catheter-related pain following prostatectomy are significant patient concerns, and it is unknown whether catheter size impacts these variables. In this study, patients undergoing prostatectomy were randomized to receive either a 16 French or 20 French catheter to assess the impact of catheter size on postoperative continence and pain.
Materials and methods: Patients were prospectively randomized to receive either a 16 French or a 20 French latex catheter at the completion of prostatectomy. Subjects were asked on postoperative day 7 to report their average catheter-related pain and the amount of opioid medication used. International Prostate… More >

Avaneesh Singh^*, Manish Kumar Bajpai

CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.3, pp. 991-1031, 2020, DOI:10.32604/cmes.2020.012503 - 15 December 2020

Abstract We have proposed a new mathematical method, the SEIHCRD model, which has an excellent potential to predict the incidence of COVID-19 diseases. Our proposed SEIHCRD model is an extension of the SEIR model. Three-compartments have added death, hospitalized, and critical, which improves the basic understanding of disease spread and results. We have studied COVID-19 cases of six countries, where the impact of this disease in the highest are Brazil, India, Italy, Spain, the United Kingdom, and the United States. After estimating model parameters based on available clinical data, the model will propagate and forecast dynamic… More >

Samarjeet Singh Siwal^1,2, Qibo Zhang^1,3,*, Adesh Kumar Saini⁴, Vijay Kumar Thakur^5,6,*

Journal of Renewable Materials, Vol.8, No.12, pp. 1543-1563, 2020, DOI:10.32604/jrm.2020.014597 - 12 November 2020

Abstract Coronaviruses are responsible for a developing budgetary, human and fatality trouble, as the causative factor of infections, for example, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has been well recognized that SARS-CoV-2 may survive under severe atmosphere circumstances. Hence, efficient containment approaches, for example, sanitizing, are crucial. Commonly, living compounds contribute a substance of chemical heterogeneity, with antiviral movement, and therefore can have efficacy as therapeutic tools toward coronavirus diseases. Here, in this review article, we have described the antimicrobialbased materials, which can be used to inhibit the spreading of the COVID-19. We have More >

Taemin Lee¹, Dongwann Kang², Kyunghyun Yoon¹, Sanghyun Seo^3,*

Intelligent Automation & Soft Computing, Vol.26, No.1, pp. 181-192, 2020, DOI:10.31209/2019.100000139

Abstract As mobile devices have tremendously developed, people can now get sensor data easily. These data are not only physical data such as temperature, humidity, gravity, acceleration, etc. but also human health data such as blood pressure, heart pulse rate, etc. With this information, Internet of Things (IoT) technology has provided many systems to support human health care. Systems for human health care support physical health care like checking blood pressure, pulse rate, etc. However, the demand for physical health care as well as mental health care is increasing. So, a system, which automatically recommends a… More >

G. N. Baltas^{1, *}, F. A. Prieto¹, M. Frantzi², C. R. Garcia-Alonso¹, P. Rodriguez^{1, 3}

CMC-Computers, Materials & Continua, Vol.64, No.3, pp. 1343-1357, 2020, DOI:10.32604/cmc.2020.011243 - 30 June 2020

Abstract During the late months of last year, a novel coronavirus was detected in Hubei, China. The virus, since then, has spread all across the globe forcing Word Health Organization (WHO) to declare COVID-19 outbreak a pandemic. In Spain, the virus started infecting the country slowly until rapid growth of infected people occurred in Madrid, Barcelona and other major cities. The government in an attempt to stop the rapssid spread of the virus and ensure that health system will not reach its capacity, implement strict measures by putting the entire country in quarantine. The duration of… More >

Eun-Joo Choi¹, So Yeon Yoo^2,*

International Journal of Mental Health Promotion, Vol.22, No.2, pp. 93-104, 2020, DOI:10.32604/IJMHP.2020.011059 - 16 June 2020

Abstract Chronic pain has a high prevalence rate and is difficult to treat because it is associated with personality, socio-psychological problems as well as physical pain, and thereby degrades one’s quality of life. This study aimed to determine whether psychosocial factors are associated with quality of life among outpatients with chronic pain. The subjects were selected from patients with chronic pain who were receiving outpatient treatment at the mental health department of a university hospital in Seoul, Korea. The participants were 100 patients and the data were collected using structured questionnaires. Patients’ quality of life More >

Rafi Mazor^1,*, Meital Mazor², Ali E. Dabiri^2,3, Bhavesh Patel², Ghassan S. Kassab²

Molecular & Cellular Biomechanics, Vol.17, No.2, pp. 93-99, 2020, DOI:10.32604/mcb.2019.08267

Abstract Cryotherapy, or more commonly known as cold therapy, is the use of low temperatures in medical treatment. The most prominent use of cryotherapy is for cryosurgery where application of very low temperatures is used to ablate diseased tissue (e.g., most commonly in dermatology). Recent research, however, shows that low temperature may modulate collagen fibers beyond the already known effects of extreme cooling on joint pain relieve and inflammation. The goal of this brief review is to outline the known effects of extreme cooling on molecular, fiber and cell physiology and to leverage these properties in… More >