Nazia Afrin^a, Yijin Mao^a, Yuwen Zhang^a,*, J. K. Chen^a, Robin Ritter^b, Alan Lampson^b, Jonathan Stohs^c

Frontiers in Heat and Mass Transfer, Vol.7, pp. 1-8, 2016, DOI:10.5098/hmt.7.7

Abstract A three-dimensional numerical simulation is conducted for a complex process in a laser-material system, which involves heat and mass transfer in a compressible gaseous phase and chemical reaction during laser irradiation on a urethane paint coated on a stainless steel substrate. A finite volume method (FVM) with a co-located grid mesh that discretizes the entire computational domain is employed to simulate the heating process. The results show that when the top surface of the paint reaches a threshold temperature of 560 K, the polyurethane starts to decompose through chemical reaction. As a result, combustion products CO₂, More >

Chad A. Reichard, Irene Makovey, Daniel A. Shoskes

Canadian Journal of Urology, Vol.22, No.1, pp. 7623-7626, 2015

Abstract Introduction: To identify a cohort of chronic pelvic pain syndrome (CPPS) patients who considered their symptoms completely resolved and analyze their demographics, clinical phenotype, treatments and NIH-Chronic Prostatitis Symptom Index (CPSI) scores.
Materials and methods: We identified 35 CPPS patients who at the follow up, reported their symptoms completely resolved (“cured”). Demographics, UPOINT phenotypes, treatments, and CPSI scores were examined. We also compared these variables to a database of 220 previously evaluated CPPS patients.
Results: Patients ranged in age from 19 to 72 years. Median follow up was 12 months. Mean change in CPSI sub scores before and after… More >

Jack Barkin

Canadian Journal of Urology, Vol.22, No.3, pp. 7847-7852, 2015

Abstract Several abstracts presented at the 2015 European Association of Urology Meeting highlighted new developments in hormone therapy for prostate cancer management. One abstract described how the luteinizing hormone-releasing hormone (LHRH)/gonadotropin-releasing hormone (GnRH) agonist leuprolide, but not the LHRH/GnRH antagonist degarelix, induced plaque instability in a mouse model. A second abstract showed that in patients with a history of severe cardiovascular disease, degarelix was associated with fewer cardiovascular events than treatment with an LHRH agonist. A third abstract showed how primary androgen-deprivation therapy was linked with increased all-cause mortality in a US registry. A fourth abstract More >

Dwayne Tun Soong Chang¹, Isaac Andrew Thyer^1,2, Dickon Hayne^1,3, Darren Jonathan Katz⁴

Canadian Journal of Urology, Vol.22, No.4, pp. 7935-7937, 2015

Abstract We report the case of a man with idiopathic lymphocytic orchitis (LO) manifested by undifferentiated testicular pain and atrophy. Conventional investigation results were unremarkable. Oral ciprofloxacin only improved the pain temporarily. Scrotal exploration surgery was performed to exclude acute testicular torsion and a biopsy was taken during surgery for histological examination. Histology revealed severe LO with reduced spermatogenesis. A trial of oral steroids was initially effective but the effect was temporary. Due to chronic pain, he eventually underwent unilateral orchidectomy. Histology confirmed the initial diagnosis of LO. He was pain-free postoperatively. Idiopathic LO is a More >

Francis X. Keeley Jr

Canadian Journal of Urology, Vol.21, No.1, pp. 7125-7125, 2014

Abstract This article has no abstract. More >

Christine N. Tran¹, Jianbo Li², Daniel A. Shoskes¹

Canadian Journal of Urology, Vol.21, No.2, pp. 7195-7200, 2014

Abstract Introduction: To evaluate the clinical phenotypes of patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using a web based online tool and to compare these clinical features with patients evaluated in a tertiary referral clinic.
Materials and methods: Data was collected from 720 men who gave complete online responses on a website which determines the UPOINT clinical phenotype in CP/CPPS and measures symptom severity with the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). This was compared to phenotype and symptom severity of 220 patients evaluated in person at a tertiary referral clinic.
Results: The web-based cohort… More >

Andrew G. Winer¹, Nicholas H. Chakiryan¹, Ryan P. Mooney¹, Daniel Verges¹, Mazyar Ghanaat¹, Atabak Allaeei², Luke Robinson², Harry Zinn², Erich K. Lang^1,2,3

Canadian Journal of Urology, Vol.21, No.4, pp. 7365-7368, 2014

Abstract Introduction: Pelvic congestion syndrome (PCS) is a complex condition of the pelvic venous system leading to nonspecific pelvic pain that was initially described in females alone. The underlying abnormalities, though diverse, all result in increased pressure in the left gonadal vein which is transmitted retrograde into the pelvic venous system. Our primary aim was to describe our findings of secondary PCS as a distinct entity from primary PCS in that it has an identifiable vascular etiology and is gender nonspecific. We also aimed to assess the adequacy of late-arterial phase CT urography (CTU) as the initial… More >

Leendert W. Schwab, Wouter M. J. Kloosterman, Jakob Konieczny, Katja Loos^*

Journal of Renewable Materials, Vol.1, No.1, pp. 73-78, 2013, DOI:10.7569/JRM.2012.634102

Abstract The papain catalyzed enzymatic synthesis of amido amines catalyzed from aromatic diamines and N-carbobenzyloxy (Z) protected amino acids (Gly, L-Leu, L-Phe) is described. The amides precipitate (yield 19–47 % depending on the amino acid used) from the reaction mixture after one amide bond is formed thus preventing the formation of diamides in all cases. Papain retains its activity in buffers with a higher pH (9 and 12) observable by the amide bond formation between 1,3-phenylene diamine and Z-L-Gly and Z-L-Phe. Aliphatic diamines (1,4-butanediamine and 1,6-hexanediamine) were used as well but amide formation could not be More >

Yongren Wu^∗, Sarah Cisewski^∗, Barton L. Sachs^†, Hai Yao^∗,†,‡

Molecular & Cellular Biomechanics, Vol.10, No.2, pp. 159-182, 2013, DOI:10.3970/mcb.2013.010.159

Abstract This study examines the effects of cartilage endplate (CEP) calcification and the injection of intervertebral disc (IVD) cells on the nutrition distributions inside the human IVD under physiological loading conditions using multiphasic finite element modeling. The human disc was modeled as an inhomogeneous mixture consisting of a charged elastic solid, water, ions (Na⁺ and Cl⁻), and nutrient solute(oxygen,glucose and lactate) phases. The effect of the endplate calcification was simulated by a reduction of the tissue porosity (i.e., water volume faction) from 0.60 to 0.48. The effect of cell injection was simulated by increasing the cell density… More >

Dean A. Tripp^1,2,3, J. Curtis Nickel³, Jennifer L. Pikard¹, Laura Katz¹

Canadian Journal of Urology, Vol.19, No.1, pp. 6081-6087, 2012

Abstract Introduction: To estimate the prevalence of chronic prostatitis (CP)-like symptoms in African adolescents, examining the impact of demographic factors, CP-like symptoms (i.e., pain, urinary) and depressive symptoms on quality of life (QoL).
Materials and methods: Community dwelling African males aged 16-19 years (M = 16.97; SD = .88; n = 166), attending secondary school participated. CP-like case identification was based on NIH-Chronic Prostatitis Symptom Index definition (NIH-CPSI; pain in perineum and/or with ejaculation and NIH-CPSI total pain score of ≥ 4 [mild] and ≥ 8 [moderate-severe]). The Patient Health Questionnaire (PHQ) assessed depressive symptoms. CP-like point prevalence… More >