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  • Open Access

    ARTICLE

    Cardiac morphology for the millennial cardiology fellow: Nomenclature and advances in morphologic imaging

    Shankar Baskar, Seth B. Gray, Erica L. Del Grippo, Onyekachukwu Osakwe, Adam W. Powell, Justin T. Tretter

    Congenital Heart Disease, Vol.13, No.5, pp. 808-810, 2018, DOI:10.1111/chd.12675

    Abstract Cardiology fellows‐in‐training, both in adult and pediatric hospitals, need structured education in regards to congenital heart disease (CHD) nomenclature. With improved survival of patients with CHD, it is not uncommon for these patients to seek care in multiple adult and pediatric hospitals. A deep understanding of CHD nomenclature would aid in providing accurate medical and surgical care for these patients. In this forum, we share our experience with such structured education and also comment on recent advances in morphologic imaging that would aid in understanding the nomenclature. More >

  • Open Access

    ARTICLE

    Focal liver lesions following Fontan palliation of single ventricle physiology: A radiology‐pathology case series

    Emily M. Engelhardt1, Andrew T. Trout2,3, Rachel M. Sheridan4, Gruschen R. Veldtman5, Jonathan R. Dillman2,3

    Congenital Heart Disease, Vol.14, No.3, pp. 380-388, 2019, DOI:10.1111/chd.12730

    Abstract Purpose: Patients who have undergone Fontan palliation of single ventricle physiol‐ ogy congenital heart disease are prone to developing focal liver lesions. In our experi‐ ence, the variety of lesions occurring in this population is greater than that described in the literature. The purpose of this study was to describe the breadth of biopsy‐ proven liver lesions in patients post–Fontan palliation of single ventricle physiology cared for at our institution.
    Methods: We retrospectively identified patients who had previously undergone the Fontan operation and had a focal liver lesion biopsied between January 2000 and June 2018. Medical records were reviewed for… More >

  • Open Access

    ARTICLE

    Brief note: Differences in intracellular localization of corn stunt spiroplasmas in magnesium treated maize.

    CLAUDIA NOME1*, PAULO CÉSAR MAGALHÃES2, ELIZABETH OLIVEIRA2, SERGIO NOME, IRMA GRACIELA LAGUNA1

    BIOCELL, Vol.33, No.2, pp. 133-136, 2009, DOI:10.32604/biocell.2009.33.133

    Abstract Maize plants infected with Spiroplasma kunkelii show symptoms similar to that of plants in a magnesium-deficient soil, and it has been shown that the spiroplasma alters the plants’ magnesium absorption. In the current study we compared changes associated to either spiroplasma infection, two soil magnesium levels and their combinations. Plant symptoms were recorded and correlated with transmission electron microscopy observations. Plants grown on a high magnesium treatment showed no macroscopical alterations nor organelle ultrastructural alterations, while plants on a low magnesium treatment showed macroscopical vein yellowing and, ultrastructurally, they had most chloroplasts and mitochondrial membranes altered. Infected plants on a… More >

  • Open Access

    REVIEW

    Microglia-precursor cell interactions in health and in pathology

    Estela M. MUÑOZ

    BIOCELL, Vol.42, No.2, pp. 41-46, 2018, DOI:10.32604/biocell.2018.07011

    Abstract Until recently, microglia were mainly known as the resident phagocytes of the brain, i.e. the ‘immunological warriors’ of the brain. However, extensive knowledge is being accumulated about the functions of microglia beyond immunity. Nowadays, it is well accepted that microglial cells are highly dynamic and responsive, and that they intervene in a dual manner in many developmental processes that shape the central nervous system, including neurogenesis, gliogenesis, spatial patterning, synaptic formation and elimination, and neural circuit establishment and maturation. The differentiation and the pool of precursor cells were also shown to be under microglia regulation via bidirectional communication. In this… More >

  • Open Access

    ARTICLE

    Histopathological patterns of ovarian lesions: A study of 161 cases

    Abdulkareem Younis SULEIMAN1, Intisar Salim PITY2, Mohammed R MOHAMMED2, Bashar Abduljabar HASSAWI2

    BIOCELL, Vol.43, No.3, pp. 175-181, 2019, DOI:10.32604/biocell.2019.06884

    Abstract Ovarian lesions are commonly encountered pathologies that cannot be categorized clinicoradiologically. Definite diagnosis is of great importance for therapeutic and prognostic purposes. Histopathology gives accurate diagnosis in most cases. Few cases need supportive tests like immunohistochemistry. Objective: to study the histomorphological diversity of ovarian lesions, their age and location in North of Iraq (Mosul and Duhok). Patients and methods: In the period extended from January 2008 to December 2011, 161 cases of ovarian lesions were collected from pathology departments in Azadi General Hospital “Duhok” and Al-Jamhori Teaching Hospital “Mosul”. Automated tissue processor was used for histologic study and Streptavidin-biotin method… More >

  • Open Access

    ARTICLE

    Mesenchymal stem cells are more effective than captopril in reverting cisplatin-induced nephropathy

    Entsar A. SAAD1, Reda S. EL-DEMERDASH2, Eman M. ABD EI-FATTAH1

    BIOCELL, Vol.43, No.2, pp. 73-80, 2019, DOI:10.32604/biocell.2019.07020

    Abstract Cisplatin is a powerful anticancer drug but its nephrotoxic effects limit its clinical use. We aimed to evaluate the effect of mesenchymal stem cells (MSCs) injection or of captopril to counteract the cisplatin-induction of nephropathy. MSCs isolation, preparation and tracking, transforming growth factor-β (TGF-β) and interleukin-10 (IL-10) expressions, kidney function tests, oxidative stress state, and histological examinations were done. Cisplatininduced nephropathy was indicated biochemically and confirmed histopathologically. MSCs treatment showed normal kidney architecture, and significantly decreased oxidative stress and TGF-β while increased IL-10 and improved kidney function tests. Rats treated with cisplatin + captopril showed noticeable kidney histopathological changes. Superior… More >

  • Open Access

    ARTICLE

    A Machine Learning Approach for MRI Brain Tumor Classification

    Ravikumar Gurusamy1, Dr Vijayan Subramaniam2

    CMC-Computers, Materials & Continua, Vol.53, No.2, pp. 91-108, 2017, DOI:10.3970/cmc.2017.053.091

    Abstract A new method for the denoising, extraction and tumor detection on MRI images is presented in this paper. MRI images help physicians study and diagnose diseases or tumors present in the brain. This work is focused towards helping the radiologist and physician to have a second opinion on the diagnosis. The ambiguity of Magnetic Resonance (MR) image features is solved in a simpler manner. The MRI image acquired from the machine is subjected to analysis in the work. The real-time data is used for the analysis. Basic preprocessing is performed using various filters for noise removal. The de-noised image is… More >

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