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  • Open Access

    ARTICLE

    Hemodynamic, biological, and right ventricular functional changes following intraatrial shunt repair in patients with flow-induced pulmonary hypertension

    Chih-Hsin Hsu1,2, Jun-Neng Roan1,3, Jieh-Neng Wang4, Chien-Chi Huang5, Chao-Jung Shih3, Jyh-Hong Chen2,6, Jing-Ming Wu4, Chen-Fuh Lam7,8

    Congenital Heart Disease, Vol.12, No.4, pp. 533-539, 2017, DOI:10.1111/chd.12479

    Abstract Objectives: Atrial septal defects may result in pulmonary hypertension and right heart remodeling. We analyzed improvements in patients with flow-induced pulmonary hypertension and the activation of endothelial progenitor cells after flow reduction.
    Design: This prospective cohort study included 37 patients who were admitted for an occluder implantation. Blood samples were collected before and after the procedure. We determined the number of endothelial progenitor cells in outgrowth colonies and serum Hsp27 concentrations. Daily performance and cardiothoracic ratio were reevaluated later.
    Results: Closure of the defect significantly reduced the pulmonary pressure and B-type natriuretic peptide levels. The cardiothoracic ratio and… More >

  • Open Access

    RESIDENT’S CORNER

    Selective arterial embolization of angiomyolipoma leading to pulmonary hypertension

    Franklin Lee, David S. Aaronson, Sarah Blaschko, Phil Barbosa, Alex K. Wu, Michael Eisenberg, Bradley A. Erickson, Jack W. McAninch

    Canadian Journal of Urology, Vol.17, No.3, pp. 5232-5235, 2010

    Abstract Objectives: To report two cases of secondary pulmonary hypertension resulting from microsphere extravasation following selective arterial embolization of renal angiomyolipoma, its diagnosis, and management.
    Methods: We reviewed the cases of two patients at the University of California, San Francisco, treated with selective arterial embolization for management of their angiomyolipoma (AML) using Tris-Acryl Gelatin Microspheres.
    Results: Both patients were women, ages 51 and 77. Indications for treatment were the following: Patient 1 was treated for a large asymptomatic AML. Patient 2 was treated for a symptomatic, bleeding AML. Both patients developed progressive hypoxia following selective arterial embolization using Tris-Acryl More >

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