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  • Open Access

    ARTICLE

    Impact of standardized clinical assessment and management plans on resource utilization and costs in children after the arterial switch operation

    Rahul H. Rathod1,2, Brittney Jurgen1,2, Rose A. Hamershock3, Kevin G. Friedman1,2, Audrey C. Marshall1,2, Mihail Samnaliev4, Dionne A. Graham3, Kathy Jenkins1,2, James E. Lock1,2, Andrew J. Powell1,2

    Congenital Heart Disease, Vol.12, No.6, pp. 768-776, 2017, DOI:10.1111/chd.12508

    Abstract Background: Standardized Clinical Assessment and Management Plans (SCAMPs) are a quality improvement initiative designed to reduce unnecessary utilization, decrease practice variation, and improve patient outcomes. We created a novel methodology, the SCAMP managed episode of care (SMEOC), which encompasses multiple encounters to assess the impact of the arterial switch operation (ASO) SCAMP on total costs.
    Methods: All ASO SCAMP patients (dates March 2009 to July 2015) were compared to a control group of ASO patients (January 2001 to February 2009). Patients were divided into “younger” (<2 years) and “older” (2–18 years) subgroups. Utilization included all cardiology visits,… More >

  • Open Access

    ARTICLE

    A Dimension-Reduction Interval Analysis Method for Uncertain Problems

    J.C. Tang1, C.M. Fu1,2

    CMES-Computer Modeling in Engineering & Sciences, Vol.113, No.3, pp. 239-259, 2017, DOI:10.3970/cmes.2017.113.249

    Abstract In this paper, an efficient interval analysis method called dimension-reduction interval analysis (DRIA) method is proposed to calculate the bounds of response functions with interval variables, which provides a kind of solution method for uncertainty analysis problems of complex structures and systems. First, multi-dimensional function is transformed into multiple one-dimensional functions by extending dimension reduction method to the interval analysis problem. Second, all the one-dimensional functions are transformed to standard quadratic form by second order Taylor expansion method. As a result, the multi-dimensional function is approximately represented by the functions that each interval variable occurs More >

  • Open Access

    ARTICLE

    Cycle Time Reduction in Injection Molding by Using Milled Groove Conformal Cooling

    Mahesh S. Shinde1,*, Kishor M. Ashtankar2

    CMC-Computers, Materials & Continua, Vol.53, No.3, pp. 207-217, 2017, DOI:10.32604/cmc.2017.053.223

    Abstract This paper presents simulation study on Milled Grooved conformal cooling channels (MGCCC) in injection molding. MGCCC has a more effective cooling surface area which helps to provide efficient cooling as compared to conventional cooling. A case study of Encloser part is investigated for cycle time reduction and quality improvement. The performance designs of straight drilled are compared with MGCCC by using Autodesk Moldflow Insight (AMI) 2016. The results show total 32.1% reduction of cooling time and 9.86% reduction of warpage in case of MGCCC as compared to conventional cooling. More >

  • Open Access

    ARTICLE

    Wall-Pressure Fluctuations of Modified Turbulent Boundary Layer with Riblets

    Hayder A. Abdulbari 1,2, Hassan D. Mahammed1, Z. Hassan, Wafaa K. Mahmood3

    FDMP-Fluid Dynamics & Materials Processing, Vol.12, No.2, pp. 86-101, 2016, DOI:10.3970/fdmp.2016.012.086

    Abstract An experimental investigation was carried out to study the response of a turbulent pressure drop fluctuations to longitudinal groove riblets, involved two configurations being triangular and spaced triangular grooves with height 600, 800, 1000 μm and peak to peak spacing 1000 μm and 2000 μm respectively. Experiments were therefore performed at free stream velocity up to 0.44 m/sec, which were corresponding to Reynolds number (Re) 53000. The development of the obtained turbulent layer downstream of the grooves was then compared with the results from the corresponding smooth-wall case. To conclude, the effect of the spaced More >

  • Open Access

    ARTICLE

    Higher-Order Line Element Analysis of Potential Field with Slender Heterogeneities

    H.-S. Wang1,2, H. Jiang3,4, B. Yang2

    CMC-Computers, Materials & Continua, Vol.51, No.3, pp. 145-161, 2016, DOI:10.3970/cmc.2016.051.145

    Abstract Potential field due to line sources residing on slender heterogeneities is involved in various areas, such as heat conduction, potential flow, and electrostatics. Often dipolar line sources are either prescribed or induced due to close interaction with other objects. Its calculation requires a higher-order scheme to take into account the dipolar effect as well as net source effect. In the present work, we apply such a higher-order line element method to analyze the potential field with cylindrical slender heterogeneities. In a benchmark example of two parallel rods, we compare the line element solution with the More >

  • Open Access

    ARTICLE

    Management of complications after surgical outlet reduction for benign prostatic obstruction

    Daniel C. Parker1, Jay Simhan1,2

    Canadian Journal of Urology, Vol.22, Suppl.5, pp. 88-92, 2015

    Abstract instruction: Introduction: Lower urinary tract symptoms are a common complaint. Surgery to debulk hyperplastic prostate tissue is indicated for men with symptoms refractory to medical therapy, or for those who cannot tolerate first-line medications. In recent decades, new endoscopic techniques have been developed to reduce the morbidity of transurethral resection of the prostate (TURP). Nonetheless, complications are still frequently encountered in the immediate, early, and remote postoperative setting.
    instruction: Materials and methods: In this review, we perform an in-depth examination of contemporary treatment strategies for long term complications of surgical outlet reduction procedures. Complications encountered in the… More >

  • Open Access

    ARTICLE

    miR-146a Inhibits Proliferation and Enhances Chemosensitivity in Epithelial Ovarian Cancer via Reduction of SOD2

    YaJie Cui*†, Kai’e She, Defu Tian§, Peilian Zhang, Xiaoyan Xin*

    Oncology Research, Vol.23, No.6, pp. 275-282, 2015, DOI:10.3727/096504016X14562725373798

    Abstract Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy, accounting for 90% of all ovarian cancer. Dysregulation of miRNAs is associated with several types of EOC. In the current research, we aimed to study the role of abnormal expression of miR-146a in the development of EOC and to elucidate the possible molecular mechanisms. Compared with control samples, mRNA expression of miR-146a was significantly decreased in EOC tissues and cell lines. Overexpression of miR-146a prohibited cell proliferation, enhanced apoptosis, and increased sensitivity to chemotherapy drugs in EOC cells. In contrast, downregulation of miR-146a promoted cell… More >

  • Open Access

    ARTICLE

    A Particle Simulation of 2-D Vessel Motions Interacting with Liquid-Sloshing Cargo

    Byung-Hyuk Lee1, Se-min Jeong2, Sung-Chul Hwang2, Jong-Chun Park3, Moo-Hyun Kim4

    CMES-Computer Modeling in Engineering & Sciences, Vol.91, No.1, pp. 43-63, 2013, DOI:10.3970/cmes.2013.091.043

    Abstract The violent free-surface motions interacting with floating vessels containing inner liquid tanks are investigated by using the newly developed Moving Particle Semi-implicit (MPS) method for 2-dimensional incompressible flow simulation. In the present numerical examples, many efficient and robust algorithms have been developed and applied to improve the overall quality and efficiency in solving various highly nonlinear free-surface problems and evaluating impact pressures compared to the original MPS method proposed by Koshizuka and Oka (1996). For illustration, the improved MPS method is applied to the simulation of nonlinear floating-body motions, violent sloshing motions and corresponding impact More >

  • Open Access

    ARTICLE

    Generic Linking of Finite Element Models for Non-Linear Static and Global Dynamic Analyses of Aircraft Structures

    A.J. de Wit1, D. Akçay Perdahcıoğlu2, T. Ludwig3, W.M. van den Brink1, A. de Boer2

    CMC-Computers, Materials & Continua, Vol.32, No.3, pp. 201-218, 2012, DOI:10.3970/cmc.2012.032.201

    Abstract Depending on the type of analysis, Finite Element (FE) models of different fidelity are necessary. Creating these models manually is a labor intensive task. This paper discusses two approaches for generating FE models of different fidelity from a single reference FE model. The models are created with a single modelling and meshing toolkit. These different fidelity models are created for use with global-local non-linear static analysis and for use with dynamic linear sub-structuring reduction method. Efficiency of the developed approaches is demonstrated via non-linear static and modal analysis of a carbon-fiber stiffened panel. More >

  • Open Access

    ARTICLE

    Numerical and Experimental Investigation to Reduction of Sedimentation of Particles in MRFs with Permanent Magnets

    Chenxi Xiong1,2, Xianghe Peng1,2,3, Chunwei Zhao1,2,4, Ning Hu1,5,6

    CMC-Computers, Materials & Continua, Vol.31, No.1, pp. 65-86, 2012, DOI:10.3970/cmc.2012.031.065

    Abstract A method to reduce the sedimentation of the ferromagnetic particles in magnetorheological fluids (MRFs) is studied with numerical simulation and experiment. It shows that, making use of the magnetic field generated by a permanent magnet put simply above an MRF, the sedimentation of the particles in the MRF can be reduced remarkably. The magnetic force on a ferromagnetic particle and that on a particle chain are computed with the finite element (FE) code ANSYS. It reveals that the magnetic force on a particle-chain is much larger than the sum of the magnetic force on each More >

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