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  • Open Access

    REVIEW

    Review: Mitochondrial apoptotic pathways

    NORA MOHAMAD, ALICIA GUTIÉRREZ, MARIEL NÚÑEZ, CLAUDIA COCCA, GABRIELA MARTÍN*, GRACIELA CRICCO, VANINA MEDINA, ELENA RIVERA, ROSA BERGOC*.

    BIOCELL, Vol.29, No.2, pp. 149-161, 2005, DOI:10.32604/biocell.2005.29.149

    Abstract Apoptosis or programmed cell death (PCD) is a physiological process characteristic of pluricellular organisms leading to self-destruction of the cell. It is therefore involved in development, homeostasis and host defense. However, a significant difference has been shown between mammalian cell apoptosis and non-mammalian cell apoptosis: mitochondria are implicated only in the former. Execution of PCD includes the release of several proapoptotic proteins from the intermembrane space of mitochondria. They could exert their actions through a caspase dependent as well as a caspase independent way. On the other hand, regulation of PCD is mainly given by More >

  • Open Access

    ARTICLE

    Coalescence and Non-coalescence Phenomena in Multi-material Problems and Dispersed Multiphase Flows: Part 2, A Critical Review of CFD Approaches

    Marcello Lappa1

    FDMP-Fluid Dynamics & Materials Processing, Vol.1, No.3, pp. 213-234, 2005, DOI:10.3970/fdmp.2005.001.213

    Abstract The physical properties of many emulsions and metal alloys strongly depend on the multiphase morphology which is controlled to a great degree by particle-particle interaction during the related processing. In the present article significant effort is devoted to illustrate the philosophy of modeling for these phenomena and some insights into the physics. Within such a context working numerical techniques that have enjoyed a widespread use over recent years are presented and/or reviewed. Finally a focused and critical comparison of these possible approaches is reported illustrating advantages and disadvantages, strengths and weaknesses, past history and future More >

  • Open Access

    ARTICLE

    Coalescence and Non-coalescence Phenomena in Multi-material Problems and Dispersed Multiphase Flows: Part 1, A Critical Review of Theories

    Marcello Lappa1

    FDMP-Fluid Dynamics & Materials Processing, Vol.1, No.3, pp. 201-212, 2005, DOI:10.3970/fdmp.2005.001.201

    Abstract The manuscript deals with a presentation of the most reliable theories introduced over the years to model particle coalescence and non-coalescence phenomena at both macroscopic and microscopic length scales (including historical developments and very recent contributions) and moves through other macrophysical mechanisms that can cause spatial separation of the fluid phases (liquid-liquid or liquid-gas) in multi-material problems, while providing a rigorous theoretical framework for deeper understanding of how drop (or bubble) migration due to gravity and/or Marangoni effects can interact cooperatively with coalescence to significantly affect the multiphase pattern formation, its evolutionary progress as well More >

  • Open Access

    ARTICLE

    Review: Possible strategies for the control and stabilization of Marangoni flow in laterally heated floating zones

    Marcello Lappa1

    FDMP-Fluid Dynamics & Materials Processing, Vol.1, No.2, pp. 171-188, 2005, DOI:10.3970/fdmp.2005.001.171

    Abstract The paper presents a comparative and critical analysis of some theoretical/experimental/numerical arguments concerning the possible stabilization of the surface-tension-driven (Marangoni) flow in the Floating Zone technique and in various related fluid-dynamic models. It is conceived as a natural extension of the focused overview published in Cryst. Res. Tech. 40(6), 531, (2005) where much room was devoted to discuss the intrinsic physical mechanisms responsible for three-dimensional and oscillatory flows in a variety of technological processes. Here, a significant effort is provided to illustrate the genesis of possible control strategies (many of which are still in a More >

  • Open Access

    CASE REPORT

    Testicular epidermoid cyst: a case report and review of the clinicopathologic features

    Joshua D. Wiesenthal, Helen Ettler1, Hassan Razvi2

    Canadian Journal of Urology, Vol.11, No.1, pp. 2133-2135, 2004

    Abstract Epidermoid cysts of the testicle are rare, benign lesions that are clinically indistinguishable from malignant germ cell tumors. A scrotal mass in a 27-year-old man was incidentally detected by his family physician, and confirmed to be intratesticular by ultrasound. Radical orchidectomy was performed revealing the pathologic diagnosis. The presentation, evaluation and management of epidermoid cysts are discussed. More >

  • Open Access

    ARTICLE

    A systematic review of randomized trials in localized prostate cancer

    Shabbir M. H. Alibhai1, Laurence H. Klotz2

    Canadian Journal of Urology, Vol.11, No.1, pp. 2110-2117, 2004

    Abstract Introduction: Most treatment studies of localized prostate cancer are observational in nature. The recent publication of a large randomized trial of radical prostatectomy (RP) versus watchful waiting (WW) has focused increased attention on the treatment of localized prostate cancer. We reviewed all published randomized trials that compared different primary treatment modalities for localized prostate cancer.
    Materials and methods: We performed a comprehensive Medline search from 1966 to March 2003 to identify all English-language randomized trials of RP, external-beam radiotherapy (EBRT), brachytherapy, watchful waiting, and primary androgen-deprivation therapy in localized prostate cancer.
    Results: Nine publications dealing with four separate… More >

  • Open Access

    RESIDENT’S CORNER

    Bladder leiomyoma: report of two cases and literature review

    S. Binsaleh1,2, J. Corcos1, M. M. Elhilali2, S. Carrier1

    Canadian Journal of Urology, Vol.11, No.5, pp. 2411-2413, 2004

    Abstract Mesenchymal tumors of the urinary bladder are rare and the majority of them are malignant. We report two cases of leiomyoma of the urinary bladder presenting with symptoms of bladder outlet obstruction. The first patient was managed with staged transurethral resections, and the second with holmium laser transurethral inoculation. The outcome was excellent in both cases. A review of the literature is also outlined. More >

  • Open Access

    REVIEW

    Review : Uterine mast cells: A new hypothesis to understand how we are born

    M. ISOLDE RUDOLPH1, I. GINA ROJAS2, ALICIA B. PENISSI3

    BIOCELL, Vol.28, No.1, pp. 1-11, 2004, DOI:10.32604/biocell.2004.28.001

    Abstract Birth is the result of complex, well-defined, and coordinated events, that are tightly regulated by endocrine, nervous, and immune responses, and take place primarily in the female reproductive tract. Various mechanisms and mediators involved in pregnancy, labor, and delivery, are highly conserved among different mammalian species and mast cells emerge as potential and crucial participants in these processes, as it is discussed in this review. More >

  • Open Access

    ARTICLE

    Review of Large Scale Computing in Electromagnetics with Fast Integral Equation Solvers

    W.C. Chew1, J.M. Song1, T.J. Cui1, S. Velamparambil1, M.L. Hastriter1, B. Hu1

    CMES-Computer Modeling in Engineering & Sciences, Vol.5, No.4, pp. 361-372, 2004, DOI:10.3970/cmes.2004.005.361

    Abstract This paper reviews recent advances in large-scale computational electromagnetics using frequency domain integral equations. It gives a brief history of methods to solve Maxwell's equations, followed by a description of various historical ages in solution technique developments. Then it describes computational electromagnetics followed by a brief description of how fast integral equation solvers such as the multilevel fast multipole algorithm (MLFMA) is constructed using the tree network. Some examples of large scale computing using MLFMA are given. Ray physics used to further accelerate the speed of MLFMA. The parallel implementation of MLFMA in a code More >

  • Open Access

    ARTICLE

    A historical review of erectile dysfunction

    Luc Valiquette

    Canadian Journal of Urology, Vol.10, Suppl.1, pp. 7-11, 2003

    Abstract Over the last three decades, there has been a significant increase in our understanding of the physiologic mechanisms responsible for erectile dysfunction. Erectile dysfunction has become a topic of considerable media and societal interest and acceptance. Paralleling the increase in knowledge has been an explosion in therapeutic options. This article will evaluate the therapeutic options, from a historical perspective of what has been available, and outline the progress that has been made. More >

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