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Search Results (22)
  • Open Access


    Predicting Dementia Risk Factors Based on Feature Selection and Neural Networks

    Ashir Javeed1,2, Ana Luiza Dallora2, Johan Sanmartin Berglund2,*, Arif Ali4, Peter Anderberg2,3, Liaqat Ali5

    CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 2491-2508, 2023, DOI:10.32604/cmc.2023.033783

    Abstract Dementia is a disorder with high societal impact and severe consequences for its patients who suffer from a progressive cognitive decline that leads to increased morbidity, mortality, and disabilities. Since there is a consensus that dementia is a multifactorial disorder, which portrays changes in the brain of the affected individual as early as 15 years before its onset, prediction models that aim at its early detection and risk identification should consider these characteristics. This study aims at presenting a novel method for ten years prediction of dementia using on multifactorial data, which comprised 75 variables. There are two automated diagnostic… More >

  • Open Access


    Epidemiology of Breast Cancer

    Chao Shang, Dongkui Xu*

    Oncologie, Vol.24, No.4, pp. 649-663, 2022, DOI:10.32604/oncologie.2022.027640

    Abstract All over the world, the most common malignancy in women is breast cancer. Breast cancer is also a significant factor of death in women. In 2020, approximately 2.3 million cases of breast cancer were newly diagnosed in women globally, and approximately 685,000 people died. Breast cancer incidence varies by region around the world, but it is all increasing. According to the current morbidity and mortality trend of breast cancer, it is estimated that by 2030, the number of incidence and deaths of breast cancer will reach 2.64 million and 1.7 million, respectively. The age-standardized incidence rate was 66.4/100,000 in developed… More >

  • Open Access


    Incidence and Related Risk Factors of Junctional Ectopic Tachycardia in Infants after Cardiac Surgery for Congenital Heart Disease

    Jae Hee Seol1,4,#, Se Yong Jung1,#, Jae Young Choi1, Han Ki Park2, Young Hwan Park2, Nam Kyun Kim1,3,*

    Congenital Heart Disease, Vol.17, No.5, pp. 569-578, 2022, DOI:10.32604/chd.2022.018436

    Abstract Objective: Junctional ectopic tachycardia is common after cardiac surgery for congenital heart disease. However, its incidence and related risk factors in infants after cardiac surgery are not well known. The objective of this study was to determine the overall incidence and related risk factors for junctional ectopic tachycardia in neonates and infants. Methods: We enrolled a total of 271 patients aged <1 year who underwent open cardiac surgery at Severance Cardiovascular Hospital from January 2018 to December 2020. Exclusion criteria were immediate postoperative mortality, other arrhythmias detected in the perioperative period, and prematurity. Result: The overall incidence of junctional ectopic… More >

  • Open Access


    Risk Factors and Gender Differences for Depression in Chilean Older Adults: A Cross-Sectional Analysis from the National Health Survey 2016–2017

    Gabriela Nazar1,2,*, Carlos-María Alcover3, Yeny Concha-Cisternas4,5, Igor Cigarroa5, Ximena Díaz-Martínez6, Mariela Gatica-Saavedra7, Fabián Lanuza8,9, Ana María Leiva-Ordónez10, María Adela Martínez-Sanguinetti11, Miquel Martorell2,12, Fanny Petermann-Rocha13,14, Claudia Troncoso-Pantoja15, Carlos Celis-Morales16

    International Journal of Mental Health Promotion, Vol.24, No.5, pp. 679-697, 2022, DOI:10.32604/ijmhp.2022.020105

    Abstract Depressive disorders are recognized as one of the most common mental health conditions across different age groups. However, the risk factors associated with depression among older people from low-and middle-income countries remains unclear. This study aims to identify socio-demographic, health and psychosocial-related factors associated with depression in Chilean older adults. A cross-sectional study was carried out in a representative sample of 1,765 adults aged ≥60 years participants from the Chilean National Health Survey 2016–2017. Depression was assessed with the Composite International Diagnostic Interview (CIDI-SF). Associations between the exposure variables and depression were investigated using Poisson regression analyses. The main findings… More >

  • Open Access


    Regorafenib-Induced Hand–Foot Skin Reaction Is More Severe on the Feet Than on the Hands

    Yuma Nonomiya*, Takashi Yokokawa, Kazuyoshi Kawakami, Kazuo Kobayashi, Takeshi Aoyama, Tomomi Takiguchi, Takahito Sugisaki, Kenichi Suzuki, Mitsukuni Suenaga, Takeru Wakatsuki, Kensei Yamaguchi, Yoshikazu Sugimoto*, Toshihiro Hama

    Oncology Research, Vol.27, No.5, pp. 551-556, 2019, DOI:10.3727/096504018X15291727589740

    Abstract Regorafenib is a multikinase inhibitor for the treatment of metastatic colorectal cancer. Regorafenib-induced hand–foot skin reaction (HFSR) is a common side effect during treatment. The reported frequency of HFSR was 80% (grade 3: 28%) in the Japanese subpopulation in the CORRECT trial; however, more detailed data regarding HFSR in terms of onset and sites of susceptibility are unclear. Additionally, the risk factors for regorafenib-induced severe HFSR are unknown. The aim of this study was to compare HFSR between the hands and feet and identify preexisting risk factors for severe HFSR in Japanese patients receiving regorafenib. We retrospectively examined the onset… More >

  • Open Access


    Dynamic Voting Classifier for Risk Identification in Supply Chain 4.0

    Abdullah Ali Salamai1, El-Sayed M. El-kenawy2, Ibrahim Abdelhameed3,*

    CMC-Computers, Materials & Continua, Vol.69, No.3, pp. 3749-3766, 2021, DOI:10.32604/cmc.2021.018179

    Abstract Supply chain 4.0 refers to the fourth industrial revolution’s supply chain management systems, which integrate the supply chain’s manufacturing operations, information technology, and telecommunication processes. Although supply chain 4.0 aims to improve supply chains’ production systems and profitability, it is subject to different operational and disruptive risks. Operational risks are a big challenge in the cycle of supply chain 4.0 for controlling the demand and supply operations to produce and deliver products across IT systems. This paper proposes a voting classifier to identify the operational risks in the supply chain 4.0 based on a Sine Cosine Dynamic Group (SCDG) algorithm.… More >

  • Open Access


    Relationship between PON-1 enzymatic activity and risk factors for pesticide poisoning in farmers from the Cienega, Jalisco, Mexico


    BIOCELL, Vol.45, No.5, pp. 1241-1250, 2021, DOI:10.32604/biocell.2021.015771

    Abstract Paraoxonase-1 (PON-1) is an enzyme that hydrolyzes organophosphate pesticides. The presence of polymorphisms in PON-1 (L55M and Q192R) decreases its enzyme activity and increases the risk of central nervous system (CNS) toxicity in occupationally exposed farmers, leading to chronic degenerative diseases and death. We studied 103 farmers in the region of Cienega Jalisco, Mexico, which were exposed mainly to organophosphate pesticides. We used serum and plasma samples to assay PON-1 activity and perform polymorphism analysis (L55M and Q192R) using qPCR and TaqMan probes, respectively. For both polymorphisms, there was high percentage of heterozygosity (55 LL = 0.19, LM = 0.75,… More >

  • Open Access


    Hypertension and Heart Failure as Predictors of Mortality in an Adult Congenital Heart Defect Population

    Cheryl Raskind-Hood1,*, Kashaine A. Gray2,3, Jayne Morgan3, Wendy M. Book4,*

    Congenital Heart Disease, Vol.16, No.4, pp. 333-355, 2021, DOI:10.32604/CHD.2021.014384

    Abstract Early intervention to prevent premature mortality is vital for adults with congenital heart defects (CHD). Anatomic complexity and comorbid conditions are thought to contribute to CHD mortality. Since hypertension (HTN) and heart failure (HF) are the comorbid conditions among the most prevalent causes of death in the United States, and commonly accompany CHD, it is crucial to evaluate whether they are reliable predictors of mortality for adults with CHD (ACHD) independent of anatomic CHD complexity. A retrospective cross-sectional analysis of ACHD, aged 18–64, with concomitant HTN and/or HF and at least one health care encounter during 2008–2010 were assessed. Of… More >

  • Open Access


    Acquired Coronary Artery Disease in Patients with Congenital Heart Disease: Issues in Diagnosis and Management

    Sotiria C. Apostolopoulou1,*, Stella Brili2, Eftihia Sbarouni3, Dimitris Tousoulis2, Konstantinos Toutouzas2

    Congenital Heart Disease, Vol.15, No.5, pp. 369-375, 2020, DOI:10.32604/CHD.2020.012092

    Abstract Objective: Acquired coronary artery disease, initially thought to rarely affect survivors of congenital heart disease, is increasingly recognized in this population, as these patients grow in age and numbers in the recent era. This study reports our experience with coronary artery disease in adults with congenital heart disease and discusses treatment issues and the existing literature. Methods: Retrospective review of all charts of adults with congenital heart disease and acquired coronary artery disease was performed. Patients’ clinical characteristics, diagnosis, risk factors, noninvasive and invasive imaging and management data were recorded. Results: Coronary artery disease was diagnosed at 35–70 of age… More >

  • Open Access


    Atrial Septal Defect in Children: The Incidence and Risk Factors for Diagnosis

    Gustaf Tanghöj1,*, Anna Lindam2, Petru Liuba3,4, Gunnar Sjöberg5, Estelle Naumburg1

    Congenital Heart Disease, Vol.15, No.5, pp. 287-299, 2020, DOI:10.32604/CHD.2020.011977

    Abstract Objective: Secundum atrial septal defect (ASD II) is a common congenital heart defect, and interatrial communications among preterm children is even more common. The objective of this study was to calculate the incidence of ASD II in children, with assessment to gestational age at birth. Further, to assess maternal, prenatal and postnatal risk factors associated with ASD II among children of different gestational age at birth. Design: This national registry based retrospective incidence study was supplemented with a national case-control study, using the Swedish Register of Congenial Heart Disease, Swedish Medical Birth Register and Statistics Sweden. All children, 0–18 years… More >

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