Gamal A. Elfar^*†, Mohamed A. Ebrahim^‡, Nehal M. Elsherbiny^*, Laila A. Eissa^*

Oncology Research, Vol.25, No.4, pp. 641-650, 2017, DOI:10.3727/096504016X14768398678750

Abstract Osteoprotegerin (OPG) is a robust antiresorptive molecule that acts as a decoy receptor for the receptor activator of nuclear factor kB ligand (RANKL), the mediator of osteoclastogenesis. This study was designed to explore the possible role of serum OPG and RANKL in detecting bone metastasis in breast cancer and its interaction with clinicopathologic parameters. Serum levels of RANKL and OPG were estimated in 44 metastatic and 36 nonmetastatic breast cancer patients using ELISA kits. Serum OPG levels were significantly reduced in patients with bone metastasis and correlated negatively with the number of bone lesions and… More >

A. Rtibi¹, M. Hasnaoui¹, A. Amahmid¹

FDMP-Fluid Dynamics & Materials Processing, Vol.9, No.2, pp. 183-207, 2013, DOI:10.3970/fdmp.2013.009.183

Abstract In this paper we present an analytical and numerical study of Soret convection in an inclined rectangular porous layer saturated with a binary fluid and subject to uniform heat fluxes. In the problem formulation, the Darcy model is considered and the results are presented for wide ranges of R_T (50 ≤ R_T ≤ 1000), θ(0°≤θ≤180°) and φ(-1 ≤ φ ≤ 1) for Le = 10, where R_T, θ, φ, and Le are the thermal Darcy-Rayleigh number, the cavity inclination, the separation parameter, and the Lewis number, respectively. An analytical solution, derived on the basis of the parallel flow approximation,… More >

Eric C. Sayre^1,2, Peter S. Bunting^3,4, Jacek A. Kopec^2,5

Canadian Journal of Urology, Vol.16, No.1, pp. 4463-4471, 2009

Abstract Introduction: Medical chart-review and self-reported questionnaire are two common methods of determining cancer screening and symptoms. We investigate the validity of these methods and therefore of a class of clinical/epidemiological studies. We compare variables on prostate cancer, any prostate-specific antigen (PSA) test, asymptomatic screening PSA, any digital rectal exam (DRE), and urinary symptoms. We used data from a 2005 case control study of PSA and metastatic prostate cancer (MPC) (253 cases and 496 controls). Data were collected from 1999 to 2002.
Methods: We calculated kappa, percent agreement (PPA) and prevalence adjusted bias adjusted kappa (PABAK). We compared… More >

J. Toribio¹, V. Kharin²

The International Conference on Computational & Experimental Engineering and Sciences, Vol.7, No.3, pp. 135-140, 2008, DOI:10.3970/icces.2008.007.135

Abstract This paper deals with the meaning and significance of the fracture mechanics approach to hydrogen assisted cracking, analyzing the question of K-dominance not only over the purely mechanical aspects, but also over the environmental (physicochemical) events. Two key factors able to violate the uniqueness of the crack growth kinetics curve v = v(K) are discussed: the role of far field (the stress-strain field which is not K-dominated) and the effect of the history of hydrogenation and crack growth. The far field is shown to have a minor effect on near-tip hydrogen diffusion, and thus it can only… More >