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  • Open Access

    ARTICLE

    A Study on the Effect of Core Strength Strengthening Training on Exercise-Induced Lumbar Injuries

    Xianghui Li*

    Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 105-114, 2022, DOI:10.32604/mcb.2022.018736

    Abstract Objective: This study aims to analyze the effect of core strength strengthening training on exercise-induced lumbar injuries. Methods: Sixteen athletes suffering from lumbar injuries were randomly divided into two groups, group A and group B. Group A performed core strength strengthening training, while group B only performed normal study and life. Before and after the experiment, the Visual Analogue Scale (VAS) score, lumbar spine mobility, Oswestry Disability Index (ODI) and overall effect evaluation of the two groups were recorded and compared. Results: After the experiment, the VAS score of group A decreased to 2.78 ± 1.89 points, the anterior flexion… More >

  • Open Access

    ARTICLE

    Influence of Nutritional Supplementation and Sports Training on the Physical Fitness of Track and Field Athletes

    Wenbing Zhu*

    Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 89-96, 2022, DOI:10.32604/mcb.2022.018522

    Abstract This study aims to understand the influence of nutritional supplementation and sports training on the physical fitness of track and field athletes. Twenty track and field athletes from Chongqing Normal University were supplemented with nutrition and trained for eight weeks. Water, sugar, and vitamins were supplemented. They were trained three times a week, two hours each time. One hour was for special track and field training, and one hour was for physical training. Before and after the experiment, the body composition, sports quality, and functional movement screening (FMS) of the athletes were tested. Compared with before the experiment, the muscle… More >

  • Open Access

    ARTICLE

    Numerical Analysis of Blood Flow through COVID-19 Infected Arteries

    Anupam Krishnan1, Anjana P. Anantharaman2,*

    Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 77-88, 2022, DOI:10.32604/mcb.2022.018369

    Abstract Computational Fluid Dynamics has become relevant in the study of hemodynamics, where clinical results are challenging to obtain. This paper discusses a 2-Dimensional transient blood flow analysis through an arterial bifurcation for patients infected with the Coronavirus. The geometry considered is an arterial bifurcation with main stem diameter 3 mm and two outlets. The left outlet (smaller) has a diameter of 1.5 mm and the right outlet (larger), 2 mm. The length of the main stem, left branch and right branch are fixed at 35 mm, 20 mm and 25 mm respectively. Viscosity change that occurs in the blood leads… More >

  • Open Access

    ARTICLE

    Nuclear Stress-Strain State over Micropillars: A Mechanical In silico Study

    Rachele Allena1,*, Denis Aubry2

    Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 1-16, 2022, DOI:10.32604/mcb.2022.018958

    Abstract Cells adapt to their environment and stimuli of different origin. During confined migration through sub-cellular and sub-nuclear pores, they can undergo large strains and the nucleus, the most voluminous and the stiffest organelle, plays a critical role. Recently, patterned microfluidic devices have been employed to analyze the cell mechanical behavior and the nucleus self-deformations. In this paper, we present an in silico model to simulate the interactions between the cell and the underneath microstructured substrate under the effect of the sole gravity. The model lays on mechanical features only and it has the potential to assess the contribution of the… More >

  • Open Access

    ARTICLE

    Effect of Resistance Training and Spirulina platensis on Expression of IL-6, Gp130 Cytokines, JAK-STAT Signaling in Male Rats Skeletal Muscle

    Abdossaleh Zar1, Fatemeh Ahmadi1, Forouzan Karimi2,*, Mozhgan Ahmadi3, Roger Ramsbottom4

    Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 51-59, 2022, DOI:10.32604/mcb.2022.018345

    Abstract The effect of resistance training and a herbal supplement on muscular signaling pathways are limited. We investigated the expression of IL-6, Gp130, JAK and STAT after resistance training, and Spirulina platensis supplementation in animal muscle. Thirty-two male Sprague Dawley rats (weight: 290 ± 20 g, and 9 weeks of age) were divided into four groups: control (CO; n = 8), Spirulina platensis supplementation (SP; n = 8), resistance exercise (RE; n = 8), and Spirulina platensis + resistance exercise (SP + RE; n = 8). The resistance exercise group trained five sessions each week for eight weeks. Spirulina 200 mg… More >

  • Open Access

    ARTICLE

    Lung Nodule Detection Based on YOLOv3 Deep Learning with Limited Datasets

    Zhaohui Bu1, Xuejun Zhang2,3,*, Jianxiang Lu4, Huan Lao5, Chan Liang2, Xianfu Xu2, Yini Wei2, Hongjie Zeng2

    Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 17-28, 2022, DOI:10.32604/mcb.2022.018318

    Abstract The early symptom of lung tumor is always appeared as nodule on CT scans, among which 30% to 40% are malignant according to statistics studies. Therefore, early detection and classification of lung nodules are crucial to the treatment of lung cancer. With the increasing prevalence of lung cancer, large amount of CT images waiting for diagnosis are huge burdens to doctors who may missed or false detect abnormalities due to fatigue. Methods: In this study, we propose a novel lung nodule detection method based on YOLOv3 deep learning algorithm with only one preprocessing step is needed. In order to overcome… More >

  • Open Access

    ARTICLE

    Comparative Study on Biomechanics of Two Legs in the Action of Single-Leg Landing in Men’s Badminton

    Gang He*

    Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 41-50, 2022, DOI:10.32604/mcb.2022.017044

    Abstract This study aims to analyze the biomechanical difference between the two legs of male badminton players when they land on one leg, thereby providing some guidance for preventing sports injury. Ten male badminton players were selected as the subjects. They did the single-leg landing movement successfully three times. The kinematic data were obtained by the Vicon infrared high-speed motion capture system. The kinetic data were obtained by the KISTLER three-dimensional forcing measuring platform. The data were processed and analyzed. The center of gravity of the right leg on the X and Y axes were 0.25 ± 0.05 and 0.21 ± 0.04 m, respectively, which were… More >

  • Open Access

    ARTICLE

    Classification of Leukemia and Leukemoid Using VGG-16 Convolutional Neural Network Architecture

    G. Sriram1, T. R. Ganesh Babu2, R. Praveena2,*, J. V. Anand3

    Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 29-40, 2022, DOI:10.32604/mcb.2022.016966

    Abstract Leukemoid reaction like leukemia indicates noticeable increased count of WBCs (White Blood Cells) but the cause of it is due to severe inflammation or infections in other body regions. In automatic diagnosis in classifying leukemia and leukemoid reactions, ALL IDB2 (Acute Lymphoblastic Leukemia-Image Data Base) dataset has been used which comprises 110 training images of blast cells and healthy cells. This paper aimed at an automatic process to distinguish leukemia and leukemoid reactions from blood smear images using Machine Learning. Initially, automatic detection and counting of WBC is done to identify leukocytosis and then an automatic detection of WBC blasts… More >

  • Open Access

    ARTICLE

    Certain Investigations on Melanoma Detection Using Non-Subsampled Bendlet Transform with Different Classifiers

    S. Poovizhi, T. R. Ganesh Babu, R. Praveena*

    Molecular & Cellular Biomechanics, Vol.18, No.4, pp. 201-219, 2021, DOI:10.32604/mcb.2021.017984

    Abstract Skin is the largest organ and outer enclosure of the integumentary system that protects the human body from pathogens. Among various cancers in the world, skin cancer is one of the most commonly diagnosed cancer which can be either melanoma or non-melanoma. Melanoma cancers are very fatal compared with non-melanoma cancers but the chances of survival rate are high when diagnosed and treated earlier. The main aim of this work is to analyze and investigate the performance of Non-Subsampled Bendlet Transform (NSBT) on various classifiers for detecting melanoma from dermoscopic images. NSBT is a multiscale and multidirectional transform based on… More >

  • Open Access

    REVIEW

    A Review of the Role of ERp57 in Cancerous and Non-Cancerous Cell Physiology and its Potential as a Therapeutic Target

    Fatemeh Rahbar1, Avid Farhang Fagheh2, Ayda Khosravi2, Siavash Shariatzadeh2,3,*, Reza Akhavan-Sigari4

    Molecular & Cellular Biomechanics, Vol.18, No.4, pp. 187-199, 2021, DOI:10.32604/mcb.2021.017750

    Abstract The protein ERp57 is a stress-responsive protein, mainly exists in the endoplasmic reticulum (ER), and a small amount in the cell membrane, cytoplasm, nucleus and mitochondria, which is involved in the signal transduction from the cell surface, the regulation process that occurs in the nucleus, and the formation of polymer protein complexes involved in DNA repair. Various degrees of ERp57 dysregulation has been observed in many types of non-communicable diseases especially in cancers. Previous studies showed that the expression of ERp57 could play a key role in occurrence and development of cancers such as breast cancer, gastric cancer, ovarian cancer,… More >

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