Jingying Lu¹, Datao Xu¹, Wenjing Quan^1,2, Julien S. Baker³, Yaodong Gu^1,*

Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 61-75, 2022, DOI:10.32604/mcb.2022.019978

Abstract Objectives: Although overuse running injury risks for the ankle and knee are high, the effect of different shoe designs on Achilles tendon force (ATF) and Patellofemoral joint contact force (PTF) loading rates are unclear. Therefore, the primary objective of this study was to compare the ATF at the ankle and the PTF and Patellofemoral joint stress force (PP) at the knee using different running shoe designs (forefoot shoes vs. normal shoes). Methods: Fourteen healthy recreational male runners were recruited to run over a force plate under two shoe conditions (forefoot shoes vs. normal shoes). Sagittal plane ankle and knee kinematics… More >

Reza Samanipour¹, Aida Pourmostafa², Adel Marzban², Sara Tabatabaee³, Hasan Bahraminasab², Amir Ali Hamidieh⁴, Amirhossein Tavakoli^4,*

Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 97-104, 2022, DOI:10.32604/mcb.2022.019080

Abstract Based on the remarkable demand for facial reconstitute or reshape fillers due to the dermal defects arising from specific diseases, trauma, or aging, several natural or synthetic materials have been investigated. Among the evaluated materials, decellularized dermis is one of the most biocompatible choices for the aim of skin tissue regenerative approaches. On the other hand, Carboxymethyl Cellulose (CMC), a synthetic polysaccharide, with the desirable degradability, biomechanical stability, and nontoxicity seems to be an acceptable reinforcement agent for decellularized dermis. Thus, in this research, an injectable soft tissue filler contained of human-derived decellularized collagen and CMC was fabricated. The cell-removal… More >

Xianghui Li^*

Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 105-114, 2022, DOI:10.32604/mcb.2022.018736

Abstract Objective: This study aims to analyze the effect of core strength strengthening training on exercise-induced lumbar injuries. Methods: Sixteen athletes suffering from lumbar injuries were randomly divided into two groups, group A and group B. Group A performed core strength strengthening training, while group B only performed normal study and life. Before and after the experiment, the Visual Analogue Scale (VAS) score, lumbar spine mobility, Oswestry Disability Index (ODI) and overall effect evaluation of the two groups were recorded and compared. Results: After the experiment, the VAS score of group A decreased to 2.78 ± 1.89 points, the anterior flexion… More >

Wenbing Zhu^*

Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 89-96, 2022, DOI:10.32604/mcb.2022.018522

Abstract This study aims to understand the influence of nutritional supplementation and sports training on the physical fitness of track and field athletes. Twenty track and field athletes from Chongqing Normal University were supplemented with nutrition and trained for eight weeks. Water, sugar, and vitamins were supplemented. They were trained three times a week, two hours each time. One hour was for special track and field training, and one hour was for physical training. Before and after the experiment, the body composition, sports quality, and functional movement screening (FMS) of the athletes were tested. Compared with before the experiment, the muscle… More >

Anupam Krishnan¹, Anjana P. Anantharaman^2,*

Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 77-88, 2022, DOI:10.32604/mcb.2022.018369

Abstract Computational Fluid Dynamics has become relevant in the study of hemodynamics, where clinical results are challenging to obtain. This paper discusses a 2-Dimensional transient blood flow analysis through an arterial bifurcation for patients infected with the Coronavirus. The geometry considered is an arterial bifurcation with main stem diameter 3 mm and two outlets. The left outlet (smaller) has a diameter of 1.5 mm and the right outlet (larger), 2 mm. The length of the main stem, left branch and right branch are fixed at 35 mm, 20 mm and 25 mm respectively. Viscosity change that occurs in the blood leads… More >

Rachele Allena^1,*, Denis Aubry²

Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 1-16, 2022, DOI:10.32604/mcb.2022.018958

Abstract Cells adapt to their environment and stimuli of different origin. During confined migration through sub-cellular and sub-nuclear pores, they can undergo large strains and the nucleus, the most voluminous and the stiffest organelle, plays a critical role. Recently, patterned microfluidic devices have been employed to analyze the cell mechanical behavior and the nucleus self-deformations. In this paper, we present an in silico model to simulate the interactions between the cell and the underneath microstructured substrate under the effect of the sole gravity. The model lays on mechanical features only and it has the potential to assess the contribution of the… More >

Abdossaleh Zar¹, Fatemeh Ahmadi¹, Forouzan Karimi^2,*, Mozhgan Ahmadi³, Roger Ramsbottom⁴

Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 51-59, 2022, DOI:10.32604/mcb.2022.018345

Abstract The effect of resistance training and a herbal supplement on muscular signaling pathways are limited. We investigated the expression of IL-6, Gp130, JAK and STAT after resistance training, and Spirulina platensis supplementation in animal muscle. Thirty-two male Sprague Dawley rats (weight: 290 ± 20 g, and 9 weeks of age) were divided into four groups: control (CO; n = 8), Spirulina platensis supplementation (SP; n = 8), resistance exercise (RE; n = 8), and Spirulina platensis + resistance exercise (SP + RE; n = 8). The resistance exercise group trained five sessions each week for eight weeks. Spirulina 200 mg… More >

Zhaohui Bu¹, Xuejun Zhang^2,3,*, Jianxiang Lu⁴, Huan Lao⁵, Chan Liang², Xianfu Xu², Yini Wei², Hongjie Zeng²

Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 17-28, 2022, DOI:10.32604/mcb.2022.018318

Abstract The early symptom of lung tumor is always appeared as nodule on CT scans, among which 30% to 40% are malignant according to statistics studies. Therefore, early detection and classification of lung nodules are crucial to the treatment of lung cancer. With the increasing prevalence of lung cancer, large amount of CT images waiting for diagnosis are huge burdens to doctors who may missed or false detect abnormalities due to fatigue. Methods: In this study, we propose a novel lung nodule detection method based on YOLOv3 deep learning algorithm with only one preprocessing step is needed. In order to overcome… More >

Gang He^*

Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 41-50, 2022, DOI:10.32604/mcb.2022.017044

Abstract This study aims to analyze the biomechanical difference between the two legs of male badminton players when they land on one leg, thereby providing some guidance for preventing sports injury. Ten male badminton players were selected as the subjects. They did the single-leg landing movement successfully three times. The kinematic data were obtained by the Vicon infrared high-speed motion capture system. The kinetic data were obtained by the KISTLER three-dimensional forcing measuring platform. The data were processed and analyzed. The center of gravity of the right leg on the X and Y axes were 0.25 ± 0.05 and 0.21 ± 0.04 m, respectively, which were… More >

G. Sriram¹, T. R. Ganesh Babu², R. Praveena^2,*, J. V. Anand³

Molecular & Cellular Biomechanics, Vol.19, No.1, pp. 29-40, 2022, DOI:10.32604/mcb.2022.016966

Abstract Leukemoid reaction like leukemia indicates noticeable increased count of WBCs (White Blood Cells) but the cause of it is due to severe inflammation or infections in other body regions. In automatic diagnosis in classifying leukemia and leukemoid reactions, ALL IDB2 (Acute Lymphoblastic Leukemia-Image Data Base) dataset has been used which comprises 110 training images of blast cells and healthy cells. This paper aimed at an automatic process to distinguish leukemia and leukemoid reactions from blood smear images using Machine Learning. Initially, automatic detection and counting of WBC is done to identify leukocytosis and then an automatic detection of WBC blasts… More >