Dawa Chyophel Lepcha^1,*, Bhawna Goyal^2,3, Ayush Dogra⁴, Ahmed Alkhayyat⁵, Prabhat Kumar Sahu⁶, Aaliya Ali⁷, Vinay Kukreja⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 1487-1573, 2025, DOI:10.32604/cmes.2025.070964 - 26 November 2025

Abstract Medical image analysis has become a cornerstone of modern healthcare, driven by the exponential growth of data from imaging modalities such as MRI, CT, PET, ultrasound, and X-ray. Traditional machine learning methods have made early contributions; however, recent advancements in deep learning (DL) have revolutionized the field, offering state-of-the-art performance in image classification, segmentation, detection, fusion, registration, and enhancement. This comprehensive review presents an in-depth analysis of deep learning methodologies applied across medical image analysis tasks, highlighting both foundational models and recent innovations. The article begins by introducing conventional techniques and their limitations, setting the… More >

Ehan Sohn¹, Sangmyung Lee¹, Sunggon Kim¹, Kiwook Sohn¹, Manish Kumar², Yongseok Son^3,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2761-2785, 2025, DOI:10.32604/cmes.2025.070888 - 26 November 2025

Abstract With the accelerated growth of the Internet of Things (IoT), real-time data processing on edge devices is increasingly important for reducing overhead and enhancing security by keeping sensitive data local. Since these devices often handle personal information under limited resources, cryptographic algorithms must be executed efficiently. Their computational characteristics strongly affect system performance, making it necessary to analyze resource impact and predict usage under diverse configurations. In this paper, we analyze the phase-level resource usage of AES variants, ChaCha20, ECC, and RSA on an edge device and develop a prediction model. We apply these algorithms… More >

Meshari D. Alanazi¹, Gehan Elsayed^2,*, Turki M. Alanazi³, Anis Sahbani⁴, Amr Yousef^5,6

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2277-2309, 2025, DOI:10.32604/cmes.2025.070726 - 26 November 2025

Abstract Traffic congestion plays a significant role in intelligent transportation systems (ITS) due to rapid urbanization and increased vehicle concentration. The congestion is dependent on multiple factors, such as limited road occupancy and vehicle density. Therefore, the transportation system requires an effective prediction model to reduce congestion issues in a dynamic environment. Conventional prediction systems face difficulties in identifying highly congested areas, which leads to reduced prediction accuracy. The problem is addressed by integrating Graph Neural Networks (GNN) with the Lion Swarm Optimization (LSO) framework to tackle the congestion prediction problem. Initially, the traffic information is… More >

Suhyeon Lee¹, Hwankuk Kim^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2657-2682, 2025, DOI:10.32604/cmes.2025.070627 - 26 November 2025

Abstract The open nature and heterogeneous architecture of Open Radio Access Network (Open RAN) undermine the consistency of security policies and broaden the attack surface, thereby increasing the risk of security vulnerabilities. The dynamic nature of network performance and traffic patterns in Open RAN necessitates advanced detection models that can overcome the constraints of traditional techniques and adapt to evolving behaviors. This study presents a methodology for effectively detecting malicious traffic in Open RAN by utilizing an Artificial-Intelligence/Machine-Learning (AI/ML) Framework. A hybrid Transformer–Convolutional-Neural-Network (Transformer-CNN) ensemble model is employed for anomaly detection. The proposed model generates final More >

Mona Almofarreh¹, Amnah Alshahrani², Nouf Helal Alharbi³, Ahmed Omer Ahmed⁴, Hussain Alshahrani⁵, Abdulrahman Alzahrani^6,*, Mohammed Mujib Alshahrani⁷, Asma A. Alhashmi⁸

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2631-2656, 2025, DOI:10.32604/cmes.2025.070545 - 26 November 2025

Abstract Zero-day attacks use unknown vulnerabilities that prevent being identified by cybersecurity detection tools. This study indicates that zero-day attacks have a significant impact on computer security. A conventional signature-based detection algorithm is not efficient at recognizing zero-day attacks, as the signatures of zero-day attacks are usually not previously accessible. A machine learning (ML)-based detection algorithm is proficient in capturing statistical features of attacks and, therefore, optimistic for zero-day attack detection. ML and deep learning (DL) are employed for designing intrusion detection systems. The improvement of absolute varieties of novel cyberattacks poses significant challenges for IDS… More >

Saeed Asadi¹, Hajar Kazemi Naeini¹, Delaram Hassanlou², Abolhassan Pishahang³, Saeid Aghasoleymani Najafabadi⁴, Abbas Sharifi⁵, Mohsen Ahmadi^6,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 1259-1301, 2025, DOI:10.32604/cmes.2025.070528 - 26 November 2025

Abstract The growing energy demand of buildings, driven by rapid urbanization, poses significant challenges for sustainable urban development. As buildings account for over 40% of global energy consumption, innovative solutions are needed to improve efficiency, resilience, and environmental performance. This paper reviews the integration of Digital Twin (DT) technologies and Machine Learning (ML) for optimizing energy management in smart buildings connected to smart grids. A key enabler of this integration is the Internet of Things (IoT), which provides the sensor networks and real-time data streams that fee/d DT–ML frameworks, enabling accurate monitoring, forecasting, and adaptive control.… More >

Tamara Zhukabayeva^1,2, Zulfiqar Ahmad^1,3,*, Nurbolat Tasbolatuly⁴, Makpal Zhartybayeva¹, Yerik Mardenov^1,4, Nurdaulet Karabayev^1,*, Dilaram Baumuratova^1,4

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2573-2599, 2025, DOI:10.32604/cmes.2025.070426 - 26 November 2025

Abstract The Industrial Internet of Things (IIoT), combined with the Cyber-Physical Systems (CPS), is transforming industrial automation but also poses great cybersecurity threats because of the complexity and connectivity of the systems. There is a lack of explainability, challenges with imbalanced attack classes, and limited consideration of practical edge–cloud deployment strategies in prior works. In the proposed study, we suggest an Impact-Aware Taxonomy-Driven Machine Learning Framework with Edge Deployment and SHapley Additive exPlanations (SHAP)-based Explainable AI (XAI) to attack detection and classification in IIoT-CPS settings. It includes not only unsupervised clustering (K-Means and DBSCAN) to extract… More >

Ngoc-Hoang-Quyen Nguyen¹, Thanh-Tung Nguyen², Anh-Cang Phan^3,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2435-2456, 2025, DOI:10.32604/cmes.2025.070419 - 26 November 2025

Abstract Blood cell disorders are among the leading causes of serious diseases such as leukemia, anemia, blood clotting disorders, and immune-related conditions. The global incidence of hematological diseases is increasing, affecting both children and adults. In clinical practice, blood smear analysis is still largely performed manually, relying heavily on the experience and expertise of laboratory technicians or hematologists. This manual process introduces risks of diagnostic errors, especially in cases with rare or morphologically ambiguous cells. The situation is more critical in developing countries, where there is a shortage of specialized medical personnel and limited access to… More > Graphic Abstract

Mudasir Ali¹, Muhammad Faheem Mushtaq², Urooj Akram², Nagwan Abdel Samee^3,*, Mona M. Jamjoom⁴, Imran Ashraf^5,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 1863-1901, 2025, DOI:10.32604/cmes.2025.070389 - 26 November 2025

Abstract Differentiating between regular and abnormal noises in machine-generated sounds is a crucial but difficult problem. For accurate audio signal classification, suitable and efficient techniques are needed, particularly machine learning approaches for automated classification. Due to the dynamic and diverse representative characteristics of audio data, the probability of achieving high classification accuracy is relatively low and requires further research efforts. This study proposes an ensemble model based on the LeNet and hierarchical attention mechanism (HAM) models with MFCC features to enhance the models’ capacity to handle bias. Additionally, CNNs, bidirectional LSTM (BiLSTM), CRNN, LSTM, capsule network More >

David Amilo^1,*, Khadijeh Sadri¹, Evren Hincal^1,2, Mohamed Hafez^3,4

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2189-2222, 2025, DOI:10.32604/cmes.2025.070298 - 26 November 2025

Abstract Breast cancer’s heterogeneous progression demands innovative tools for accurate prediction. We present a hybrid framework that integrates machine learning (ML) and fractional-order dynamics to predict tumor growth across diagnostic and temporal scales. On the Wisconsin Diagnostic Breast Cancer dataset, seven ML algorithms were evaluated, with deep neural networks (DNNs) achieving the highest accuracy (97.72%). Key morphological features (area, radius, texture, and concavity) were identified as top malignancy predictors, aligning with clinical intuition. Beyond static classification, we developed a fractional-order dynamical model using Caputo derivatives to capture memory-driven tumor progression. The model revealed clinically interpretable patterns: More >