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  • Open Access

    ARTICLE

    Open radical prostatectomy after transurethral resection: perioperative, functional, oncologic outcomes

    Charalampos Fragkoulis, Athanasios Pappas, Georgios Theocharis, Georgios Papadopoulos, Georgios Stathouros, Konstantinos Ntoumas

    Canadian Journal of Urology, Vol.25, No.2, pp. 9262-9267, 2018

    Abstract Introduction: This study aims to evaluate whether there are differences in perioperative, functional, and oncologic outcomes following radical retropubic prostatectomy (RRP) between patients who previously underwent transurethral resection of the prostate (TURP) and those who did not. Materials and methods: A total of 35 patients diagnosed with prostate cancer (clinical stages T1a or T1b) after TURP who subsequently underwent RRP and completed at least one year of follow-up were included in group A. These patients were matched 1:1 with a control cohort (group B, n = 35) based on age, body mass index (BMI), prostate-specific antigen (PSA)… More >

  • Open Access

    ARTICLE

    The comparative effectiveness of quadratus lumborum blocks and paravertebral blocks in radical cystectomy patients

    Austin J. Lee1, Jonathan G. Yabes2, Nathan Hale3, Ronald L. Hrebinko3, Jeffrey R. Gingrich3, Jodi K. Maranchie3, Mina M. Fam3, Robert M. Turner II3, Benjamin J. Davies3, Bruce Ben-David4, Bruce L. Jacobs3

    Canadian Journal of Urology, Vol.25, No.2, pp. 9255-9261, 2018

    Abstract Introduction: Multimodal analgesia is an effective strategy for managing postoperative pain and reducing opioid dependence. The quadratus lumborum block (QLB) and paravertebral block (PVB) are two regional anesthesia techniques that enhance multimodal pain management. In this study, we aimed to compare the efficacy of these two approaches in patients undergoing radical cystectomy. Materials and methods: A retrospective review was conducted on patients who underwent radical cystectomy between 2014 and 2016. Patients were divided into two groups based on the type of regional anesthesia received: bilateral continuous paravertebral blocks (n = 125) or bilateral single-shot quadratus lumborum blocks… More >

  • Open Access

    ARTICLE

    Improving the utility of clinical phenotyping in interstitial cystitis/painful bladder syndrome: from UPOINT to INPUT

    Alice Crane, Jessica Lloyd, Daniel A. Shoskes

    Canadian Journal of Urology, Vol.25, No.2, pp. 9250-9254, 2018

    Abstract Introduction: The UPOINT phenotyping system has proven effective in classifying patients with urologic pelvic pain syndromes in a clinically meaningful way and guiding multimodal therapy. While highly successful in men with chronic prostatitis/chronic pelvic pain syndrome (CPPS), its utility is more limited in patients with interstitial cystitis/painful bladder syndrome (IC/PBS). This is because all IC/PBS patients, by definition, exhibit urinary and organ-specific symptoms. Furthermore, the AUA guidelines recommend a sequential tiered approach to treatment rather than the concurrent multimodal strategy used in UPOINT. Therefore, we aimed to modify the UPOINT system to make it more practical… More >

  • Open Access

    ARTICLE

    Supine percutaneous nephrolitotripsy in septuagenarian and octogenarian patients: outcomes of a case-control study

    Fábio C. M. Torricelli, Guilherme K. M. Ogawa, Fábio C. Vicentini, Giovanni S. Marchini, Alexandre Danilovic, Miguel Srougi, William C. Nahas, Eduardo Mazzucchi

    Canadian Journal of Urology, Vol.25, No.2, pp. 9245-9249, 2018

    Abstract Introduction: Currently, there is limited data evaluating the outcomes of supine percutaneous nephrolithotomy (PCNL) in septuagenarian and octogenarian patients. This study aims to compare the perioperative outcomes of supine PCNL in elderly patients (≥70 years) with those of a younger population (<70 years). Materials and methods: A matched case-control study was conducted from January 2009 through December 2015 using our prospectively maintained kidney stone database. The case group consisted of patients aged over 70 years, while the control group included patients under 70 years. Patients were randomly matched based on Guy’s Stone Score as a surrogate for… More >

  • Open Access

    ARTICLE

    Stone culture in patients undergoing percutaneous nephrolithotomy: a practical point of view

    Amihay Nevo1,2, Roy Mano1,2, Ohad Shoshani1,2, Gherman Kriderman1,2, Eran Schreter1,2, David Lifshitz1,2

    Canadian Journal of Urology, Vol.25, No.2, pp. 9238-9244, 2018

    Abstract Introduction: This study aims to determine the clinical yield of stone culture in patients undergoing percutaneous nephrolithotomy (PCNL) and to identify those who may benefit from this test, particularly in predicting postoperative infections and guiding antimicrobial therapy. Materials and methods: We reviewed our institutional database for all patients who underwent PCNL between 2005 and 2017 and from whom both urine culture (UC) and stone culture (SC) results were available. The primary endpoint was the development of systemic inflammatory response syndrome (SIRS) within 48 hours post-procedure. Risk factors for SIRS and for stone colonization with highly resistant pathogens… More >

  • Open Access

    REVIEW

    Emerging, newly-approved treatments for lower urinary tract symptoms secondary to benign prostatic hypertrophy

    Hannah Pham, Pranav Sharma

    Canadian Journal of Urology, Vol.25, No.2, pp. 9228-9237, 2018

    Abstract Introduction: Oral therapy with alpha-blockers or 5-alpha reductase inhibitors remains the most common treatment for men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). For patients who progress or fail medical therapy, the standard of care continues to be transurethral resection of the prostate (TURP), a procedure with well-documented and durable outcomes. However, over the past decade, emerging minimally invasive options for LUS secondary to BPH have been developed, offering promising results with fewer side effects commonly associated with TURP, such as retrograde ejaculation and erectile dysfunction.
    Materials and methods: A literature review… More >

  • Open Access

    LEGENDS IN UROLOGY

    LEGENDS IN UROLOGY

    Colonel David G. McLeod

    Canadian Journal of Urology, Vol.25, No.2, pp. 9221-9227, 2018

    Abstract This article has no abstract. More >

  • Open Access

    EDITORIAL

    Prostate Cancer CRPC Stage M0 and M1: Do We Need Stage M0.5?

    Leonard G. Gomella

    Canadian Journal of Urology, Vol.25, No.2, pp. 9220-9220, 2018

    Abstract This article has no abstract. More >

  • Open Access

    RESIDENT’S CORNER

    Percutaneous nephrolithotomy in an 8-week-old infant

    Albert S. Lee1, Diana K. Bowen2, Seth Vatsky3, Stephen A. Zderic2, Gregory E. Tasian2

    Canadian Journal of Urology, Vol.25, No.3, pp. 9363-9365, 2018

    Abstract We report successful percutaneous nephrolithotomy (PCNL) in an 8-week-old, 4.12 kg infant with a combined stone burden of > 2 cm in a solitary kidney. The patient was born with thoracolumbar myelomeningocele and had developed recurrent urinary tract infections. Her size precluded retrograde intrarenal surgery and shockwave lithotripsy would be unlikely to clear the stone burden. Stone analysis revealed hydroxyapatite and carbonate apatite stones, and metabolic work up revealed hypercalciuria for which chlorothiazide was started. To our knowledge, this is the youngest patient to undergo PCNL reported in the literature. More >

  • Open Access

    RESIDENT’S CORNER

    Urothelial metaplasia of the seminal vesicle and ejaculatory duct associated with crossed-fused renal ectopia and Hutch diverticulum of the bladder

    Ksenia Chezar1, Geoffrey Gotto2, Shaun Medlicott1, Kiril Trpkov1

    Canadian Journal of Urology, Vol.25, No.3, pp. 9360-9362, 2018

    Abstract The presence of urothelial epithelial metaplasia in a seminal vesicle is an exceptionally rare finding. We describe a unique case of urothelial metaplasia of the seminal vesicle and ejaculatory duct, found in a radical prostatectomy specimen from a patient with complex urogenital anatomy. A 70-year-old patient with organ confined (pT2) prostatic adenocarcinoma (Gleason score 3+4 = 7) had a right-sided Hutch diverticulum and a left crossed-fused renal ectopia. Although the histogenesis of urothelial metaplasia in the seminal vesicle remains unclear, in the patient presented herein it likely developed as a consequence of the previously unrecognized More >

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