Yongqiang Li^1,#, Changxin Lai^1,#, Chengchen Zhang², Alexa Singer¹, Suhao Qiu¹, Boming Sun², Michael S. Sacks³, Yuan Feng^1,*

Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 245-251, 2019, DOI:10.32604/mcb.2019.07441

Abstract Surgeries such as implantation of deep brain stimulation devices require accurate placement of devices within the brain. Because placement affects performance, image guidance and robotic assistance techniques have been widely adopted. These methods require accurate prediction of brain deformation during and following implantation. In this study, a magnetic resonance (MR) image-based finite element (FE) model was proposed by using a coupled Eulerian-Lagrangian method. Anatomical accuracy was achieved by mapping image voxels directly to the volumetric mesh space. The potential utility was demonstrated by evaluating the effect of different surgical approaches on the deformation of the… More >

Akisue Kuramoto^1,*, Hitoshi Kimura², Norio Inou²

Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 235-243, 2019, DOI:10.32604/mcb.2019.08123

Abstract Comfortable bedding is usually designed subjectively because of the difficulty in performing a quantitative evaluation. This paper proposes a quantitative evaluation method of comfortableness of beddings. The bedding shape determining how comfortable an individual may feel in using it depends on the body shape and normal posture of individuals. The internal physical load is expected to relate to the comfortableness of bedding. However, only a few quantitative discussions exist on the relation between the comfortableness of bedding and physical load. This study proposes a new evaluation method of physical load in a relaxed posture. The… More >

Ali. E. Dabiri^1,2,*, Richard Leigh³, Ghassan S. Kassab¹

Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 225-233, 2019, DOI:10.32604/mcb.2019.07962

Abstract Stroke is a life-threatening event that is expected to more than double over the next 40 years. Approximately 85% of strokes are ischemic in nature and result from thromboembolic occlusion of a major cerebral artery or its branches. One of the diagnostic methods for detection of the cerebral ischemia is the gadolinium-enhanced MRI imaging. It is mainly used in patients to detect brain tissue damaged by an ischemic stroke and brain hemorrhage. These techniques are expensive, require sophisticated machines and are time consuming. A recent study in acute stroke patients showed gadolinium leakage into ocular… More >

Farshid GOLSHANI1, Barat Ali FAKHERI¹, Mahmood SOLOUKI¹, Nafiseh MAHDINEZHAD¹, Majid Reza KIANI FERIZ²

BIOCELL, Vol.43, No.3, pp. 225-232, 2019, DOI:10.32604/biocell.2019.07547

Abstract ITS (Internal Transcription Spacer of nuclear ribosomal DNA) regions method was applied to identify and study the phylogenetic relationships existing between 41 individuals of Crocus, including 8 species collected in Iran (4 crop and 8 wild individuals) and 16 species (2 crop and 27 wild individuals) already registered in GenBank (NCBI). PCR amplifications were performed using the primer designed on the nucleotide sequence of nuclear region (ITS). A total of 12 sequences were obtained and registered in NCBI database. In particular, 4 of these sequences were not already present in the scientific library. Nucleotide… More >

Mohammad UBAIDILLAH^1,2, Miswar FAPERTA^1,2, Kyung-Min KIM¹

BIOCELL, Vol.43, No.3, pp. 215-224, 2019, DOI:10.32604/biocell.2019.07549

Abstract Abiotic stresses, such as drought and salinity, adversely affect plant growth and productivity. Comparison between non transgenic and transgenic rice harboring CaMsrB2 gene, which induces tolerance to abiotic stress, is important to observe response of gene under abiotic stress. Phytohormone showed a tendency to increase under the drought stress or salinity stress in the transgenic plant. RT-PCR analysis showed that gene expression and phytohormone levels under abiotic stress, to be closely related. The CaMsrB2 gene is related to the expression of JA and ABA hormones. Therefore, the level of expression of these genes and hormones was More >

Chunhua YANG^1,2,3, Ye TIAN^1,2,3

BIOCELL, Vol.43, No.3, pp. 207-214, 2019, DOI:10.32604/biocell.2019.07258

Abstract Sperm-associated antigen 9 (SPAG9) expression is increased in prostate tissues of prostate cancer patients. This experimental study aimed to investigate the role of SPAG9 in bone metastasis of prostate cancer. Immunohistochemical analysis showed that SPAG9 staining was positive in 81.67% of 240 cases of prostatic carcinoma but only in 6.67% of 120 cases of benign prostate hyperplasia. Strong PAG9 staining was positively correlated with Gleason score and bone metastasis in 240 prostate cancer patients (p < 0.05), but not with the age or serum prostatespecific antigen level (p > 0.05). PC-3 cells were transfected with shRNA… More >

Jie REN¹, Qian LIANG²

BIOCELL, Vol.43, No.3, pp. 199-206, 2019, DOI:10.32604/biocell.2019.07128

Abstract This study aimed to investigate the role of high mobility group box-1 (HMGB1) expression in oral squamous cell carcinoma; HMGB1 promoted the proliferation and invasion of oral squamous cell carcinoma via activating epithelial-mesenchymal transformation (EMT). In this study, RNA transfection was used to silence the expression of HMGB1 in oral squamous cell carcinoma cells. CCK-8, cell clone formation and trans-well assays were used to detect the proliferation and invasion of cells before and after HMGB1 silencing. qRT-PCR and Western blot were used to detect changes in EMT marker protein expression before and after transfection.… More >

Tong MA^{1, §}, Fafen WANG^{2, §}, Xiaohui WANG¹

BIOCELL, Vol.43, No.3, pp. 191-198, 2019, DOI:10.32604/biocell.2019.06989

Abstract Cervical cancer (CC), has been identified as one of the most frequent malignant tumors all over the world, with high mortality in females. A growing number of investigations have confirmed that long noncoding RNAs (lncRNAs) play a crucial role in the progression of multiple cancers. Nonetheless, the biological function and regulatory mechanism of LINC01772 in CC haven’t been explored so far. In this study, LINC01772 expression was found to be upregulated in tissues and cells of CC. Knocking down LINC01772 suppressed CC cell proliferation, migration and epithelial-mesenchymal transition (EMT) process. Through molecular mechanism assays,… More >

Xu Zhang¹, Wenpeng Lu^1,*, Fangfang Li^2,3, Xueping Peng³, Ruoyu Zhang¹

CMC-Computers, Materials & Continua, Vol.61, No.2, pp. 601-616, 2019, DOI:10.32604/cmc.2019.06045

Abstract Sentence semantic matching (SSM) is a fundamental research in solving natural language processing tasks such as question answering and machine translation. The latest SSM research benefits from deep learning techniques by incorporating attention mechanism to semantically match given sentences. However, how to fully capture the semantic context without losing significant features for sentence encoding is still a challenge. To address this challenge, we propose a deep feature fusion model and integrate it into the most popular deep learning architecture for sentence matching task. The integrated architecture mainly consists of embedding layer, deep feature fusion layer, More >

Jing Liu^1,5, Jingbing Li^1,*, Jieren Cheng¹, Jixin Ma², Naveed Sadiq³, Baoru Han⁴, Qiang Geng⁵, Yang Ai⁵

CMC-Computers, Materials & Continua, Vol.61, No.2, pp. 889-910, 2019, DOI:10.32604/cmc.2019.06034

Abstract In order to solve the problem of patient information security protection in medical images, whilst also taking into consideration the unchangeable particularity of medical images to the lesion area and the need for medical images themselves to be protected, a novel robust watermarking algorithm for encrypted medical images based on dual-tree complex wavelet transform and discrete cosine transform (DTCWT-DCT) and chaotic map is proposed in this paper. First, DTCWT-DCT transformation was performed on medical images, and dot product was per-formed in relation to the transformation matrix and logistic map. Inverse transformation was undertaken to obtain… More >