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  • Open Access

    REVIEW

    Immunotherapy in the treatment of advanced prostate cancer

    Bob Djavan1, Kathleen Nelson2, Amir Kazzazi1, Aron Bruhn1, Helen Sadri1, Alejandro Gomez-Pinillos3, Anna C. Ferrari3

    Canadian Journal of Urology, Vol.18, No.5, pp. 5865-5874, 2011

    Abstract Prostate cancer is a complex disease, and treatment selection is informed by numerous variables depending on the stage of disease. Moreover, patient expectations and the impact of treatment-related adverse events may infl uence treatment choices. Available treatment options over the course of the disease have included surgery, radiation therapy, hormonal therapy, immunotherapy, and chemotherapy. This complexity requires an understanding of a wide range of treatment options and the support of a multidisciplinary team that involves urologists, radiation oncologists, diagnostic radiologists, pathologists, and medical oncologists. Collaboration among these physicians allows for a comprehensive treatment strategy that… More >

  • Open Access

    BOOK REVIEW

    The Little Black Book of Urology, 3rd Edition

    Pamela Ellsworth

    Canadian Journal of Urology, Vol.18, No.5, pp. 5864-5864, 2011

    Abstract This article has no abstract. More >

  • Open Access

    LEGENDS IN UROLOGY

    LEGENDS IN UROLOGY

    Arthur Smith

    Canadian Journal of Urology, Vol.18, No.5, pp. 5861-5863, 2011

    Abstract This article has no abstract. More >

  • Open Access

    EDITORIAL

    How Many Clicks Does It Take To Get To The Middle Of An EHR?

    Leonard G. Gomella

    Canadian Journal of Urology, Vol.18, No.5, pp. 5860-5860, 2011

    Abstract This article has no abstract. More >

  • Open Access

    RESIDENT’S CORNER

    Hypercreatinemia: think beyond acute kidney injury

    Ankur Gupta1, Mohan Biyani1, Mudit Gupta2, Marc Eric Saltel3

    Canadian Journal of Urology, Vol.18, No.6, pp. 6066-6068, 2011

    Abstract Urinary bladder rupture associated with severe hypercreatinemia is a rare clinical presentation. We herein report a 60-year-old interesting patient who was found to have intraperitoneal bladder rupture and pseudo-renal failure. High rate of suspicion and timely diagnosis is the key in management of this condition, which led to complete recovery in our patient. More >

  • Open Access

    RESIDENT’S CORNER

    A rare presentation of nephrogenic adenoma: multiple upper tract lesions in a female patient

    Dock Winston1, Jennifer K. Yates2, Ravi Munver1,2, Debra Fromer1,2

    Canadian Journal of Urology, Vol.18, No.6, pp. 6064-6065, 2011

    Abstract Nephrogenic adenomas are rare benign lesions of the urinary tract occurring most frequently in the bladder of male patients. We report the case of a female patient presenting with gross hematuria, which lateralized to the left ureter on cystoscopy. At the time of ureteroscopy, two polypoid lesions were identified in an upper and lower pole calyx, which were found on biopsy to be nephrogenic adenomas. In addition to reporting this case, we review the literature for the pathophysiology of nephrogenic adenomas. More >

  • Open Access

    RESIDENT’S CORNER

    Renal autotransplantation following long segment iatrogenic ureteric injury

    Ke Jia Teo, Chin Tiong Heng, David Consigliere, Ho Yee Tiong

    Canadian Journal of Urology, Vol.18, No.6, pp. 6060-6063, 2011

    Abstract The authors describe a case of iatrogenic right ureteric injury post duodenectomy and right hemi-colectomy. Renal autotransplantation was chosen as the treatment for the upper ureteric injury. This was successfully performed and the renal function of the transplanted kidney was subsequently preserved. The advantages and disadvantages of this approach are discussed. More >

  • Open Access

    CLINICAL TRIALS

    Open clinical uro-oncology trials in Canada

    Eric Winquist, George Rodrigues

    Canadian Journal of Urology, Vol.18, No.6, pp. 6054-6059, 2011

    Abstract This article has no abstract. More >

  • Open Access

    HOW I DO IT

    Management of pelvic organ prolapse

    Faisal Ahmed, Tiffany Sotelo

    Canadian Journal of Urology, Vol.18, No.6, pp. 6050-6053, 2011

    Abstract Symptomatic pelvic organ prolapse can afflict up to 10% of women. Urinary incontinence, voiding dysfunction or difficulty possibly related to bladder outlet obstruction are common symptoms. Infrequently hydronephrosis or defecatory dysfunction can be seen. The management of pelvic organ prolapse (POP) should start with adequate assessment of all pelvic floor complaints. If a patient is not symptomatic, surgical intervention is usually not indicated. While the use of a variety of graft materials are available today including porcine, dermal and synthetic grafts, that are used in some surgical approaches to pelvic organ prolapse, other more conservative More >

  • Open Access

    MINIMALLY INVASIVE AND ROBOTIC SURGERY

    Impact of margin status at 37 months after robot assisted radical prostatectomy

    Jonathan N. Warner1, Rafael N. Nunez1, Chinedu O. Mmeje1, Thomas V. Colby2, Robert G. Ferrigni1, Mitchell R. Humphreys1, Paul E. Andrews1, Erik P. Castle1

    Canadian Journal of Urology, Vol.18, No.6, pp. 6043-6049, 2011

    Abstract Introduction: We evaluate the impact of margin length, location, and pathologic stage on biochemical recurrence (BCR) after robot assisted radical prostatectomy (RARP) at 37 months of follow up.
    Materials and methods: A total of 1420 patients underwent a robot assisted radical prostatectomy between March 2004 and May 2010. Patients who received adjuvant therapy, those who never achieved an undetectable prostate-specific antigen (PSA), and those who had less than 18 months of follow up were excluded. Patients were then divided and evaluated based on margin status.
    Results: In total, 419 patients were included in the analysis. Eighty-three had a… More >

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