Diane K. Newman

Canadian Journal of Urology, Vol.33, No.3, pp. 499-504, 2026, DOI:10.32604/cju.2026.086225 - 29 June 2026

Abstract This article has no abstract. More >

Kevin R. Loughlin

Canadian Journal of Urology, Vol.33, No.3, pp. 497-498, 2026, DOI:10.32604/cju.2026.078441 - 29 June 2026

Abstract This article has no abstract. More >

Daxun Luo^#, Bixiao Wang^#, Haifeng Song, Chaoyue Ji, Weiguo Hu, Bo Xiao, Boxing Su, Yubao Liu^*, Jianxing Li^*

Canadian Journal of Urology, Vol.33, No.3, pp. 623-634, 2026, DOI:10.32604/cju.2026.076790 - 29 June 2026

Abstract Objectives: Urinary stone composition critically influences treatment selection and recurrence prevention, yet current intraoperative assessment remains imprecise. This study aims to achieve intraoperative prediction of stone composition by applying a deep convolutional neural network (CNN) to routinely captured endoscopic images. Methods: We retrospectively studied endoscopic images from stone-breaking surgeries in Beijing Tsinghua Changgung Hospital during 2022-12–2024-12. Images were captured before and after laser lithotripsy. Based on postoperative infrared spectroscopy, stones were divided into five categories. In total, 1780 images (1167 from RIRS, 613 from PCNL) were included and split into training and testing sets at… More >

Nicola Fazaa^1,#, Kamil Malshy^2,#,*, Yuval Shafran¹, Ameer Nsair¹, Etan Eigner¹, Melissa Atallah¹, Shadie Badaan¹, Kirolos Meilika², Ariel Zisman¹

Canadian Journal of Urology, Vol.33, No.3, pp. 515-526, 2026, DOI:10.32604/cju.2026.076687 - 29 June 2026

Abstract Urethral stricture disease remains a challenging clinical entity within contemporary urology, requiring interventions that achieve sustained urethral patency while preserving functional outcomes. Established modalities such as urethral dilation, endoscopic urethrotomy, and urethroplasty using autologous grafts provide effective treatment for many patients. However, they are constrained by morbidity, graft contraction, and suboptimal success in complex or recurrent strictures. These inherent limitations have stimulated growing investigation of therapeutic strategies. Among device-based innovations, drug-coated balloon dilation, exemplified by the Optilume™, combines mechanical expansion with localized antiproliferative drug delivery and represents a significant evolution in endoscopic management. Pharmacologic adjuncts… More >

Jianlin Xie^1,#, Jingde Wu¹, Qingwei Zhang¹, Yuanqi Guo¹, Xiande Huang^2,*

Canadian Journal of Urology, Vol.33, No.3, pp. 723-728, 2026, DOI:10.32604/cju.2026.075856 - 29 June 2026

Abstract Background: Congenital nephrogenic diabetes insipidus (CNDI) is most frequently caused by mutations in the AVPR2 gene. Patients exhibit persistent polyuria due to renal insensitivity to antidiuretic hormone. Chronic high urine output predisposes to bladder dysfunction and upper urinary-tract dilatation, notably hydronephrosis. Although pharmacotherapy can partially reduce urine volume, its capacity to reverse established hydronephrosis is limited. Clean intermittent catheterization (CIC), a mainstay in managing neurogenic bladder, warrants investigation regarding its utility in CNDI-associated hydronephrosis.
Case Description: A 9-year-old Chinese boy presented with lifelong polydipsia and polyuria, with a peak 24-h urine output of approximately 7100 mL. Renal ultrasonography… More >

Xiaoxiao Guo^1,2,#, Mingyu Chang^1,2,#, Gangyue Hao^1,2, Fengbo Zhang^3,*, Haoran Xia^1,2,*

Canadian Journal of Urology, Vol.33, No.3, pp. 573-582, 2026, DOI:10.32604/cju.2026.075599 - 29 June 2026

Abstract Background: Benign prostatic hyperplasia (BPH) is prevalent among aging men. Whether exposure to internet-derived health information is associated with disease awareness and symptom burden at initial diagnosis remains unclear. Methods: We conducted a cross-sectional study of 400 newly diagnosed BPH outpatients. Participants were classified by prior exposure to internet-derived BPH content. BPH awareness and International Prostate Symptom Scores (IPSS) were compared using the Mann-Whitney U test and multivariate linear regression adjusted for age, education, and disposable income. Stratified analyses were performed according to educational attainment, disposable income, and content format. Results: Exposure to internet-derived BPH content… More >

Mutlay Sayan^1,*, Yetkin Tuac², Zhiyu Qian^3,4, Alexander P. Cole^3,4, Jonathan E. Leeman¹, Martin T. King¹, Paul L. Nguyen¹, Anthony V. D’Amico¹

Canadian Journal of Urology, Vol.33, No.3, pp. 583-591, 2026, DOI:10.32604/cju.2026.074677 - 29 June 2026

Abstract Objectives: Under-grading exists in up to 7% of patients undergoing radical prostatectomy (RP) for prostate cancer (PC). We assessed whether underrepresented race and ethnicity disproportionately increased the odds of adverse pathology at RP in patients with biopsy Gleason score 6 or 7 PC at high-risk for upgrading and/or upstaging at RP based on age and PC indices at presentation. Methods: This retrospective cohort study analyzed 76,474 patients in the National Cancer Database (2015–2021) with biopsy Gleason score 6 or 7 N0M0 PC. Odds ratio (OR) at RP of adverse pathology defined as prostatectomy (p) Gleason… More >

Mehmet Adıyeke¹, Suna Yıldırım Karaca¹, S. Anil Ari¹, Rüyam Ercenk¹, Mücahit Furkan Balci², İbrahim Karaca^1,*

Canadian Journal of Urology, Vol.33, No.3, pp. 611-621, 2026, DOI:10.32604/cju.2026.074502 - 29 June 2026

Abstract Objectives: Stress urinary incontinence (SUI) is a prevalent condition that impairs quality of life; while midurethral sling (MUS) surgery is the standard treatment, intraurethral bulking injection offers a minimally invasive alternative. This study aimed to compare the efficacy and safety of intraurethral cross-linked hyaluronic acid/dextranomer (CLHA/Dx, DEXSUI^®) injection with midurethral sling surgery in the treatment of stress urinary incontinence in women. Methods: This retrospective study included women who presented with stress urinary incontinence to İzmir Bakırçay University, Çiğli Training and Research Hospital between January 2024 and June 2025. Patients underwent either midurethral sling surgery or intraurethral… More >

Sofia Fontanet^*, Julio F. Calderón-Cortéz, Edgar Suquilanda, Fernando Gaona, Alejandro García Navarro, Marta Piqueras

Canadian Journal of Urology, Vol.33, No.3, pp. 537-544, 2026, DOI:10.32604/cju.2026.074254 - 29 June 2026

Abstract Objectives: Nowadays, bladder neck contracture treatment reported is both bladder neck incisions and resection. Also, different energies have been described. This study aimed to describe and compare surgical techniques and energy sources used in Hospital Universitari de Vic. Methods: retrospective study of patients with a diagnosis of bladder neck contracture that required endoscopic surgical treatment between 2000 and 2024. Preoperative, operative, and postoperative characteristics were analysed. At the end of follow-up, the patient’s status was asymptomatic, under urethral dilatations, or with a permanent catheter. Results: 60 patients were included. Mean age was 71.1 years (SD =… More >

Guancan Liang^#, Jian Pan^#, Ruixiang Dai, Ziyi Lin, Xunbao Wang, Teng Hou, Zhicheng Luo, Xiaoming Wang^*

Canadian Journal of Urology, Vol.33, No.3, pp. 563-571, 2026, DOI:10.32604/cju.2026.074252 - 29 June 2026

Abstract Background: The causal link between mental illness and prostatitis remains inconclusive, largely due to heterogeneity and potential confounders. This study explored the causal link between mental illness and prostatitis in men using Mendelian randomization (MR), and offered recommendations for enhancing future research. Methods: Publicly accessible genome-wide association study (GWAS) data were accessed via the IEU OpenGWAS platform and FinnGen database for this research. The inverse variance weighted (IVW) approach served as the primary Mendelian randomization analysis, while MR-Egger, weighted median, weighted mode, and simple mode methods were additionally applied to evaluate potential relationships between prostatitis… More >