Daniel M. Bernad¹, Alan Dal Pra¹, Cintia Baule¹, Benicio N. Frey², Sergio Faria¹

Canadian Journal of Urology, Vol.20, No.4, pp. 6868-6870, 2013

Abstract Androgen deprivation therapy (ADT) is commonly used in the treatment of prostate cancer and is associated with several side effects including psychiatric disorders. We present an unusual case of a 62-year-old man with high risk prostate cancer that developed de novo psychosis after starting luteinizing hormone-releasing hormone (LHRH) agonists and discuss possible mechanisms to explain such fndings. This case report highlights the importance of continuing assessment and monitoring of potential emotional and behavioral symptoms in prostate cancer patients treated with ADT. More >

Avik Som^1,2, Li Xiao³, Rui Zhu⁴, Charles C. Guo³, Lianchun Xiao⁵, Priya Rao³, Eleni Efstathiou¹, Angabin Matin⁴, Shi-Ming Tu¹

Canadian Journal of Urology, Vol.20, No.4, pp. 6860-6867, 2013

Abstract Introduction: A small subset of young men die from seminoma. Studying these high risk, clinically atypical seminomas (CASs)—aggressive tumors with visceral metastases and chemotherapy resistance—may provide clues to the nature of drug resistance and the origin of testicular cancers. We explored the possibility that these seminomas are a unique clinical and biologic entity with intrinsic yolk sac tumor (YST) features.
Materials and methods: We assayed available archived tissue samples (n = 22) for chemotherapy-resistance markers found in YSTs. Specifically, we analyzed tissues and clinical histories from patients with CASs (those who had visceral metastases and recurrent disease),… More >

Jeffrey M. Woldrich, Ronald D. Im, Fiona M. Hughes-Cassidy, Lejla Aganovic, Kyoko Sakamoto

Canadian Journal of Urology, Vol.20, No.4, pp. 6855-6859, 2013

Abstract Introduction: To evaluate magnetic resonance imaging (MRI) utility in intratesticular and extratesticular scrotal diseases.
Materials and methods: Two radiologists retrospectively reviewed images of patients who underwent ultrasound followed by MRI, categorizing them as intratesticular or extratesticular and malignant, benign, indeterminate, or inadequate study. For patients who underwent surgical excision, pathologic results were also correlated to the presurgical ultrasound and MRI diagnoses.
Results: Of 69 cases, 38 were intratesticular lesions and 31 were extratesticular lesions. MRI and ultrasound diagnoses were discordant in 21 (55.32%) intratesticular and 19 (61.3%) extratesticular lesions. MRI diagnosis was malignant after an indeterminate ultrasound in… More >

Farshid Siadat, Jenna Sykes, Theodorus H. Van der Kwast

Canadian Journal of Urology, Vol.20, No.4, pp. 6854-6854, 2013

Abstract This article has no abstract. More >

Pierre Olivier Fiset¹, Armen Aprikian², Fadi Brimo¹

Canadian Journal of Urology, Vol.20, No.4, pp. 6848-6853, 2013

Abstract Introduction: The detection of prostate carcinoma relies on adequate sampling. We aimed to evaluate whether core length is a significant biopsy parameter in the detection of cancer, especially in the low risk cancer category group.
Materials and methods: We retrospectively analyzed pathology reports of 197 patients (2196 biopsy cores) undergoing initial transrectal ultrasound-guided biopsy. A multivariate analysis of age, total prostate-specific antigen (PSA) concentration, prostate gland volume, total number of cores, and length of biopsy cores was performed. Secondary analyses included stratification by Gleason score. Single core analysis was done to calculate a workable cut-off value for… More >

Robert L. Segal¹, Kambiz Tajkarimi², Arthur L. Burnett¹

Canadian Journal of Urology, Vol.20, No.4, pp. 6844-6847, 2013

Abstract Introduction: Current non-surgical strategies employed to treat erectile dysfunction (ED) target the vascular component of erection physiology. The Viberect handheld device (Reflexonic, LLC, Chambersburg, PA, USA) is a new FDA-cleared ED treatment, which exploits vibratory stimulation of genital afferent nerves for provoking erections. The aim of this study was to evaluate the clinical feasibility of the Viberect device for the achievement of penile erection and rigidity.
Materials and methods: Subjects for this study were five healthy men (mean age 26.4 years) with normal erectile function as measured by responses to the International Index of Erectile Function –… More >

Scott Johnson¹, Gabriel Fiscus¹, Gary S. Sudakoff², R. Corey O’Connor¹, Michael L. Guralnick¹

Canadian Journal of Urology, Vol.20, No.4, pp. 6840-6843, 2013

Abstract Introduction: To evaluate the use of ultrasound (US) at the time of percutaneous suprapubic catheter (SPC) placement. US has been recommended as a way to minimize complications, such as bowel injury, during percutaneous SPC placement, yet there is limited data supporting this recommendation.
Materials and methods: A retrospective chart review was performed on patients undergoing percutaneous SPC placement from 2002 to 2011. The method of percutaneous SPC placement (cystoscopic and/or ultrasound guidance, blind) was recorded and patients were subdivided into groups based on the use of US. The need to modify the approach based on US findings… More >

Krishna Ramaswamy, Tracy Marien, Alon Mass, Michael Stifelman, Ojas Shah

Canadian Journal of Urology, Vol.20, No.4, pp. 6833-6839, 2013

Abstract Introduction: To determine whether a simplified approach to estimate renal function based on preoperative computerized tomography (CT) imaging correlates with nuclear renography (NR) following surgical treatment of ureteropelvic junction obstruction (UPJO).
Materials and methods: We reviewed the charts of 47 patients who underwent robotic assisted laparoscopic pyeloplasty (RALP) for UPJO who had performed preoperative and postoperative nuclear renography (NR) and preoperative CT imaging. Twenty patients satisfied our inclusion criteria. We calculated differential renal function by measuring parenchymal thickness at the upper pole, midpole and lower pole regions of the kidney on the preoperative CT. Distances were measured… More >

Ronak Gor¹, Daniel J. Canter^1,2

Canadian Journal of Urology, Vol.20, No.4, pp. 6832-6832, 2013

Abstract This article has no abstract. More >

Adam D. Berneking, Henry M. Rosevear, Eric J. Askeland, Mark R. Newton, Michael A. O’Donnell, James A. Brown

Canadian Journal of Urology, Vol.20, No.4, pp. 6826-6831, 2013

Abstract Introduction: Recent evidence suggests that radical cystectomy may be underutilized in elderly patients, despite literature supporting acceptable morbidity/mortality in this population. However, there is a paucity of literature reporting complications in a standardized manner. Therefore, we evaluated the morbidity and mortality of octogenarians treated with radical cystectomy using the modified Clavien complication reporting system.
Materials and methods: We retrospectively reviewed 443 consecutive patients undergoing radical cystectomy at our institution between January 2000 and April 2010. Patients who underwent cystectomy for benign conditions were excluded, leaving 359 for analysis. Baseline demographic and perioperative data were reviewed and all… More >