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  • Open Access

    ARTICLE

    Crack Growth Modeling for Mixed-mode Problems

    A.P.Cisilino1, M.H. Aliabadi2

    Structural Durability & Health Monitoring, Vol.6, No.3&4, pp. 213-238, 2010, DOI:10.3970/sdhm.2010.006.213

    Abstract This paper presents a review of the dual boundary element method for modeling crack growth in two-dimensional and three-dimensional mixed mode problems. The modeling strategy for crack coalescence using the DBEM is presented and comparisons are made with alternative solutions where available. Also presented are three-dimensional multiple crack growth and microcrack growth problems. More >

  • Open Access

    ARTICLE

    Identification of Material Parameters for Structural Analyses

    W. Brocks1, I. Scheider2

    Structural Durability & Health Monitoring, Vol.6, No.3&4, pp. 189-212, 2010, DOI:10.3970/sdhm.2010.006.189

    Abstract Material parameters are adjustable coefficients in constitutive equations of the mechanical behaviour. Their identification requires a combined experimental and numerical approach, which results in a generally ill-posed inverse problem. Methods commonly applied in computational mechanics like optimisation and neural networks are addressed, and problems like sensitivity, uniqueness and stability are discussed. The cohesive model for describing ductile tearing is chosen as practical example to substantiate the general considerations. More >

  • Open Access

    ARTICLE

    Experimental and Numerical Investigation of 3D Mixed-Mode Crack Problems in Structures

    H.A. Richard1, M. Fulland2, G. Kullmer1, N.-H. Schirmeisen1

    Structural Durability & Health Monitoring, Vol.6, No.3&4, pp. 161-188, 2010, DOI:10.3970/sdhm.2010.006.161

    Abstract Fracture processes in real structures are in many cases of a three dimensional (3D) character. In this paper some basic problems of 3D-fracture processes are considered and discussed, in particular for general mixed-mode loading conditions, when modes I and II and III are superimposed. For experimental investigations an AFM-specimen is under consideration, while numerical simulations are carried out with the program ADAPCRACK3D. More >

  • Open Access

    ARTICLE

    Facts and Effects to be Considered when Validating 2D and 3D UD Composite Failure Conditions - experiences from participation in the World-Wide-Failure-Exercise

    R. G. Cuntze1

    Structural Durability & Health Monitoring, Vol.6, No.3&4, pp. 123-160, 2010, DOI:10.3970/sdhm.2010.006.123

    Abstract The paper deals with the validation of 2D and 3D failure conditions of unidirectional (UD) composites composed of endless fibres and thermoset matrices. The generation of these failure conditions is shortly described and then applied to test cases of the World-Wide-Failure-Exercises WWFE-I and II, organized by Qinetic in the past 20 years. The derivation of the conditions for the brittle fracture failure experiencing UD lamina material was based on the author's so-called Failure Mode Concept (FMC) which basically builds up on the hypotheses of Beltrami and Mohr-Coulomb. The generally applicable FMC is applied here to UD material. Essential topics of… More >

  • Open Access

    ARTICLE

    A Simple Model for the Evaluation of Constitutive Laws for the Computer Simulation of Fatigue-Driven Delamination in Composite Materials

    Ugo Galvanetto, Paul Robinson, Agostino Cerioni, Carlos Lopez Armas

    Structural Durability & Health Monitoring, Vol.5, No.2, pp. 161-190, 2009, DOI:10.3970/sdhm.2009.005.161

    Abstract This paper presents a simple mathematical model to investigate various formulations of interface elements which are used to simulate fatigue driven delamination in composite materials. To illustrate the effectiveness of the model it is used to evaluate the performance of several different static constitutive laws and damage definitions coupled with a particular fatigue degradation strategy. It is shown that the model can be used to readily assess the robustness and reliability of the different formulations by examining hundreds of thousands of sets of parameter values in a rational and efficient manner. More >

  • Open Access

    ARTICLE

    Vibration Analysis of Damaged Circular Arches with Varying Cross-section

    E. Viola1, F. Tornabene2

    Structural Durability & Health Monitoring, Vol.1, No.2, pp. 155-170, 2005, DOI:10.3970/sdhm.2005.001.155

    Abstract In this paper, generalized differential quadrature techniques are applied to the computation of the in-plane free vibrations of thin and thick non-uniform circular arches in undamaged and damaged configurations, when various boundary conditions are considered. Structural damage is represented by one crack in different positions and with various damage levels. The crack present in a structural member can be considered as a local stiffness reduction at the fracturing section, which changes the dynamic behaviour of the structure. Much effort has been devoted to dealing with in-plane free vibration analysis of circular arches, but only a few researchers have studied cracked… More >

  • Open Access

    ABSTRACT

    Investigation on Energy Characteristic of RBCs Deformability: A Quantitative Analysis of Extending and Retracting Curves Based on AFM

    Dong Chen1, Xiang Wang1,*, Fuzhou Tang2, Yajin Zhao1

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 150-150, 2019, DOI:10.32604/mcb.2019.07071

    Abstract Deformability is a fundamental property of the cells and tissues of living organisms, which is commonly detected to indicate the state of the cells. And the cell deformability usually depends on the methods that we used, which is easy to be confused. The present research is designed to explore the energy characteristic of red blood cell deformability, based on a quantitative analysis of extending-retracting curves acquired from atomic force microscopy. ATP-depleted red blood cells are prepared by treatment with free-glucose Ringer solution. Our results clearly show that the Youngs’ modulus of erythrocyte is closely depended on the concentration of intracellular… More >

  • Open Access

    ABSTRACT

    The Effect of the Elongation of the Proximal Aorta on the Estimation of Aortic Wall Distensibility

    Stamatia Pagoulatou1,*, Mauro Ferraro1, Bram Trachet1,2, Georgios Rovas1, Vasiliki Bikia1, Dionysios Adamopoulos3, Lindsey Crowe3, Jean-Paul Vallée3, Nikolaos Stergiopulos1

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 148-149, 2019, DOI:10.32604/mcb.2019.07346

    Abstract This article has no abstract. More >

  • Open Access

    ABSTRACT

    Rationally Designed Synthetic Protein Hydrogels with Predictable and Controllable Mechanical Properties

    Ying Li1, Bin Xue2, Wenxu Sun2, Junhua Wu2, Wenting Yu2, Meng Qin2, Wei Wang2, Yi Cao2,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 147-147, 2019, DOI:10.32604/mcb.2019.07027

    Abstract A key challenge in biomaterials research is to produce synthetic hydrogels that can replicate the diverse mechanical properties of the naturally occurring tissues for various biomedical applications, including tissue engineering, stem cell and cancer research, cell therapy, and immunomodulation. However, currently, the methods that can be used to control the mechanical properties of hydrogels are very limited and are mainly focused only on the elasticity of hydrogels. In this work, combining single molecule force spectroscopy, protein engineering and theoretical modeling, we show that synthetic protein hydrogels with predictable mechanical properties can be rationally designed using protein building blocks with known… More >

  • Open Access

    ABSTRACT

    Microspheres Modified with the Heparin Increasing the Length of Molecular Linker to Better Capture the Endotoxin

    Qi Dang1, Chun-Gong Li1, Xin-Xin Jin1, Ya-Jin Zhao1, Xiang Wang1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 146-146, 2019, DOI:10.32604/mcb.2019.07074

    Abstract Endotoxin is a a very powerful and toxic inflammatory stimulator usually leading to the sepsis occurred. In order to remove endotoxin better through hemoperfusion, it is a pretty choice to increase the length of molecular linker on adsorbents. In this study, we chose the heparin as a molecular linker because of its being anticoagulant linear polysaccharide. Heparin as a linker was covalently immobilized on the chloromethylated polystyrene microspheres (Ps) and then connected with L-phenylalanine (Phe) forming the Ps-Hep-Phe structure to adsorbed endotoxin better. The property of microspheres was characterized by Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, zeta potential and… More >

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