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  • Open Access

    ARTICLE

    Ureteroscopy for nephrolithiasis in transplanted kidneys

    Ryan Swearingen, William W. Roberts, J. Stuart Wolf Jr.

    Canadian Journal of Urology, Vol.22, No.2, pp. 7727-7731, 2015

    Abstract Introduction: While percutaneous nephrolithotomy (PCNL) is often the procedure of choice for renal and ureteral calculi in transplant kidneys, retrograde ureteroscopy (URS) is a less frequently applied but excellent option if stone burden is small. We retrospectively examined nine surgical cases performed in seven patients in what appears to be the largest single institutional series reported to date.
    Materials and methods: Seven patients underwent nine retrograde URS between June of 2009 and September of 2013, by two endourologists. These cases were reviewed retrospectively.
    Results: Among the nine procedures, we were able to address the stone(s) endoscopically… More >

  • Open Access

    ARTICLE

    Staged urethroplasty: comparison of early functional results and quality of life in mesh graft and buccal mucosa technique

    Daniel Pfalzgraf1,2, Luis Kluth1, Philip Reiss1, Margit Fisch1, Roland Dahlem1

    Canadian Journal of Urology, Vol.22, No.2, pp. 7720-7726, 2015

    Abstract Introduction: To assess bothersome results of surgery and changes in quality of life (QoL) in patients with two-staged urethral reconstruction. In patients requiring two-staged urethroplasty a functional corpus spongiosum is usually absent, and complications such as urinary dribbling, ejaculation problems and penile deviation can be expected. Data on these complications, patient satisfaction and QoL is limited.
    Materials and methods: Retrospective analysis by chart review and a standardized questionnaire of 19 consecutive patients with urethral strictures treated by two-staged urethroplasty with buccal-mucosa-graft or mesh-graft.
    Results: Overall success rate was 84%. Mean follow up 11.2 months, mean length… More >

  • Open Access

    ARTICLE

    Knowledge of erectile dysfunction and pelvic floor disorders among young adults: a cross-sectional study

    Lee A. Richter1, Robert E. Gutman1, Eshetu Tefera2, Allison Estep1, Cheryl B. Iglesia1

    Canadian Journal of Urology, Vol.22, No.2, pp. 7715-7719, 2015

    Abstract Introduction: The prevalence of pelvic floor disorders (PFD) in aging women is comparable to the prevalence of erectile dysfunction (ED) in aging men. The objective of this study was to assess young adults' familiarity with the definition, prevalence, etiology, and treatment of PFD and ED.
    Materials and methods: Women and men aged 18-40 years completed a validated survey (Prolapse and Incontinence Knowledge Quiz) to assess knowledge of urinary incontinence (UI) and pelvic organ prolapse (POP). Both groups completed a similar questionnaire created to assess knowledge of ED. Participants were asked to estimate the prevalence of these… More >

  • Open Access

    ARTICLE

    Weighted Gleason scores do not outperform standard clinical Gleason scores

    Antonio Cusano1, Peter Haddock1, Max Jackson1, Ilene Staff2, Joseph R. Wagner1

    Canadian Journal of Urology, Vol.22, No.2, pp. 7709-7714, 2015

    Abstract Introduction: Predicting patient survival rates following radical prostatectomy remains an area of clinical interest. We compared the ability of standard clinical Gleason scores and alternative 'weighted' Gleason scores to predict pathology, margin status and recurrence in prostate cancer.
    Materials and methods: Patients who underwent robotic radical prostatectomy performed by a single surgeon between Jan 2007 - Dec 2008 were included. Tumor at the inked margin in pathologic samples was considered a positive margin. Recurrence was defined as PSA ≥ 0.2 or the institution of salvage therapy. Standard pathologic Gleason scores were recorded. The proportion of tumor… More >

  • Open Access

    ARTICLE

    Influence of statin use on clinicopathological characteristics of localized prostate cancer and outcomes obtained after radical prostatectomy: a single center study

    Susanna Cattarino1, Thomas Seisen1,2, Sarah J. Drouin1, Raphaële Renard-Penna1, Priscilla Leon1,2, Eva Comperat3, Pierre Mozer1, Olivier Cussenot1,2, Morgan Rouprêt1,2

    Canadian Journal of Urology, Vol.22, No.2, pp. 7703-7708, 2015

    Abstract Introduction: To assess the impact of statin use on biochemical recurrence (BCR) of prostate cancer after radical prostatectomy (RP).
    Materials and methods: Data from all men treated with robot-assisted laparoscopic RP (RALRP) for localized prostate cancer between 2009 and 2014 at our institution were prospectively collected: age, body mass index (BMI), statin-use status, preoperative prostate-specific antigen (PSA) level, clinical T stage, biopsy Gleason score (bGS), D'Amico risk group, pathological T stage, specimen Gleason score (sGS), multifocality, perineural invasion, positive surgical margins and time to BCR. Univariate and multivariate analysis were performed to test associations between statin… More >

  • Open Access

    ARTICLE

    Impact of post prostate biopsy hemorrhage on multiparametric magnetic resonance imaging

    Ali-Reza Sharif-Afshar1, Tom Feng1, Steven Koopman1, Christopher Nguyen2, Quanlin Li3, Eugene Shkolyar1, Rola Saouaf2, Hyung L. Kim1

    Canadian Journal of Urology, Vol.22, No.2, pp. 7698-7702, 2015

    Abstract Introduction: Hemorrhage induced by prostate biopsy can interfere with the interpretation of prostate magnetic resonance imaging (MRI).
    Materials and methods: We reviewed 101 patients who had prostate multiparametric MRI (MP-MRI) and radical prostatectomy.
    Results: On MRI obtained within 4 weeks following the biopsy, hemorrhage was seen in 26/36 (72.2%) patients. Patients having a MRI between 4-6 weeks of the biopsy had hemorrhage in 8/14 (57.1%) cases. After 6 weeks, hemorrhage was less common but still present in 24/46 (52%) patients. There were five patients who had prostate MRI prior to biopsy and served as a control… More >

  • Open Access

    ARTICLE

    Prognostic significance of cystoscopy findings following neoadjuvant chemotherapy for muscle-invasive bladder cancer

    Ahmed M. Mansour1, Mark S. Soloway2, Ahmed Eldefrawy3, Rakesh Singal4, Shivam Joshi5, Murugesan Manoharan5

    Canadian Journal of Urology, Vol.22, No.2, pp. 7690-7697, 2015

    Abstract Introduction: To evaluate the potential significance of cystoscopy findings following neoadjuvant chemotherapy (NAC) as prognostic indicator in patients undergoing radical cystectomy for muscle-invasive bladder cancer (MIBC).
    Materials and methods: Patients who received NAC prior to radical cystectomy for MIBC were analyzed. Patients were divided into two groups according to cystoscopy performed after two cycles of NAC: responders and non-responders. Univariate analysis was performed to analyze associations between observed response to chemotherapy and pT stage, pN stage and tumor downstaging. Logistic regression modeling was fitted to evaluate predictors for extravesical disease and pathologic downstaging. Kaplan-Meier analysis was… More >

  • Open Access

    REVIEW

    Botulinum neurotoxin A for overactive bladder treatment: advantages and pitfalls

    Că​lin Chibelean, Ioan Alin Nechifor-Boilă​

    Canadian Journal of Urology, Vol.22, No.2, pp. 7681-7689, 2015

    Abstract Introduction: Overactive bladder (OAB) syndrome is a special condition characterized by urgency, with or without urinary urge incontinence (UUI), associated to frequency and nocturia, with important consequences on patients' quality of life (QoL). Administered as intradetrusor injections, botulinum neurotoxin type A (BoNT/A) is a new, promising, minimally invasive treatment option for OAB patients, non-compliant to conventional antimuscarinics. The aim of our study was to perform a systematic review of the literature concerning the efficiency and safety of different BoNT/A products in the treatment of OAB.
    Materials and methods: A thorough PubMed search was performed. After having… More >

  • Open Access

    LEGENDS IN UROLOGY

    LEGENDS IN UROLOGY

    Frans M. J. Debruyne

    Canadian Journal of Urology, Vol.22, No.2, pp. 7678-7680, 2015

    Abstract This article has no abstract. More >

  • Open Access

    EDITORIAL

    The testosterone storm

    Leonard G. Gomella

    Canadian Journal of Urology, Vol.22, No.2, pp. 7677-7677, 2015

    Abstract This article has no abstract. More >

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