TY  - EJOU
AU  - Xiao, Jia-Wang 
AU  - Wang, Qi-Guang 
AU  - Zhang, Duan-Zhen 
AU  - Cui, Chun-Sheng 
AU  - Han, Xiumin 
AU  - Zhang, Po 
AU  - Hou, Chuangju 
AU  - Zhu, Xian-Yang 

TI  - Clinical outcomes of percutaneous or surgical closure of ruptured sinus of Valsalva aneurysm
T2  - Structural and Congenital Heart Disease

PY  - 2018
VL  - 13
IS  - 2
SN  - 3071-1738

AB  - <b>Objective:</b> To evaluate the clinical efficacy, safety, and long-term outcomes of percutaneous closure (PC) and surgical repair of ruptured sinus of Valsalva aneurysm (RSVA).<br/>
<b>Methods:</b> Eighty-five consecutive patients with RSVA were included in this study. Patients were
considered candidates for PC if they met the criterion, surgical repair was performed on patients
who were unsuitable or failed PC. Of them, 30 patients underwent PC, while the other 55 patients
had surgical repair.<br/>
<b>Results:</b> RSVA was successfully occluded in 29 of 30 patients who were treated by PC. The mean
narrowest diameter at the ruptured site was 6.45 ± 1.60 mm measured by aortography. One
patient developed serious occluder-related aortic regurgitation and underwent surgery. The success rate of the interventional approach was 96.7%. In the surgical group, 23 patients underwent
repair of combined RSVA and ventricular septal defect. The hospital mortality rate of the surgical
approach was 3.57%. During a median follow-up of 83 months (8–152 months), the improvement
in NYHA functional class in the PC group was significantly greater than those in the surgical group
(P < .01). One patient died of infective endocarditis in the surgical group. There were no further
serious complications.<br/>
<b>Conclusions:</b> PC is a safe alternative to surgical repair for patients with isolated RSVA. Surgical
repair is more suitable for those who have multiple cardiac lesions requiring surgical treatment or
failed PC.
KW  - aneurysm
KW  -  outcome
KW  -  percutaneous
KW  -  surgery
KW  -  Valsalva

DO  - 10.1111/chd.12572