@Article{chd.12827,
AUTHOR = {Line Marie Holst, Faridis Serrano, Lara Shekerdemian, Hanne Berg Ravn, Danielle Guffey, Nancy S. Ghanayem, Sonia Monteiro},
TITLE = {Impact of feeding mode on neurodevelopmental outcome in infants and children with congenital heart disease},
JOURNAL = {Structural and Congenital Heart Disease},
VOLUME = {14},
YEAR = {2019},
NUMBER = {6},
PAGES = {1207--1213},
URL = {http://www.techscience.com/schd/v14n6/38898},
ISSN = {3071-1738},
ABSTRACT = {<b>Objective:</b> To investigate the impact of feeding mode on neurodevelopmental
outcomes in children with congenital heart defects.<br/>
<b>Design:</b> A retrospective cohort study of 208 children with congenital heart disease
(CHD), who had surgery from 1 January 2013 until 31 December 2016 at Texas
Children’s Hospital, Houston, TX, US.<br/>
<b>Settings:</b> University Hospital, Developmental Outcome Clinic.<br/>
<b>Outcomes measures:</b> Standardized cognitive scores were assessed with Capute
Scales and motor development with Revised Gesell Developmental Schedules. We
analyzed anthropometrics, mode of feeding, surgical complexity, syndrome, and gen‐
der as predictors of developmental outcomes at four time points: hospital discharge,
and 6, 12, and 24 months of age.<br/>
<b>Results:</b> Mode of feeding is associated with neurodevelopmental outcome in children
with CHD. Children on enteral feeding tubes had significantly lower developmental
quotient (DQ) scores in cognition, communication, and motor function at 12 and 24
months compared to orally fed children. There were greater proportions of develop‐
mental delays (DQ < 70) in enteral tube fed children at the 6, 12, and 24 months visits.
Further, there was a strong association between presence of enteral feeding tube,
syndrome, and developmental outcome. Greater surgical complexity, weight gain and
ethnicity were not associated with the developmental outcomes.<br/>
<b>Conclusions:</b> Our findings suggest that the presence of an enteral feeding tube fol‐
lowing corrective congenital heart surgery are at increased risk of neurodevelopmen‐
tal delays at 12 and 24 months.},
DOI = {10.1111/chd.12827}
}