@Article{CHD.2020.013127,
AUTHOR = {Jiachen Li, Xianchao Jiang, Sim-eng Zhang, Jinyang Liu, Yajuan Zhang, Jun Yan, Shoujun Li, Qiang Wang},
TITLE = {Mid-Term Outcome of Surgical Treatment in Pediatric Patients with Ebstein’s Anomaly: A Single-Center Cohort Study},
JOURNAL = {Structural and Congenital Heart Disease},
VOLUME = {15},
YEAR = {2020},
NUMBER = {5},
PAGES = {387--397},
URL = {http://www.techscience.com/schd/v15n5/40259},
ISSN = {3071-1738},
ABSTRACT = {<b>Background:</b> Ebstein’s anomaly (EA) is a malformation of the tricuspid valve (TV) and myopathy of the right ventricle (RV). Surgery is now the main
treatment for the defect. <b>Objective:</b> To summarize our surgical results and experience based on patients with EA who were under 7 years of age and treated with
different surgical treatments. <b>Design:</b> Single-center cohort study of Ebstein’s
anomaly. <b>Setting:</b> China. <b>Participants:</b> 80 patients under 7 years old who were
diagnosed of EA and underwent different surgical treatments were consecutively
enrolled in our research from January 2010 to December 2019. <b>Results:</b> The median age of the 80 patients at the time of surgery was 3.63 years. Sixty-four
(80.00%) patients underwent biventricular repair while 13 (16.25%) underwent
1.5-ventricle repair. With the median follow-up 27.50 months, the mid-term survival of the total cohort, 1.5-ventricular repair and biventricular repair was
82.35%, 91.67% and 100%, respectively. The mid-term freedom from reoperation
rate was 97.50%, 92.31% and 98.44%, respectively. Mild, moderate and severe
TR before surgery occurred in 6 (7.50%), 18 (22.50%) and 56 (70.00%), respectively. The early outcomes of 78 patients were 65 (83.33%), 11 (14.11%) and
2 (2.56%); the mid-term outcomes of 72 patients were 49 (68.06%), 19 (26.38%)
and 4 (5.56%). Both early and mid-term valve regurgitations were significantly
decreased (<i>p</i> < 0.001) compared with preoperative condition. No more severe regurgitation occurred (<i>p</i> = 0.404), though some early mild regurgitation became acceptable moderate regurgitation during mid-term follow-up (<i>p</i> = 0.036). <b>Conclusion:</b>
The overall effect of surgical treatment for EA was good, and most patients could
receive biventricular repair at an early stage. The reoperation rate and mid-term
mortality were both low and TR was significantly improved.},
DOI = {10.32604/CHD.2020.013127}
}