TY - EJOU AU - Caruso, Elio AU - Farruggio, Silvia AU - Calvaruso, Davide AU - Petruccelli, David Fabio AU - Ruiz, David Angel Ortiz AU - Mambro, Corrado Di AU - Agati, Salvatore TI - Management of “Wall to Wall Heart” in a Transient Neonatal Tricuspid Regurgitation T2 - Structural and Congenital Heart Disease PY - 2021 VL - 16 IS - 3 SN - 3071-1738 AB - We present a case of a one-day-old newborn, without prenatal diagnosis, referred to our cardiologic intensive care unit in critical condition presenting sub-cyanosis and peripheral oxygen saturation of 80%. Echocardiography diagnosis was tricuspid valve dysplasia with severe regurgitation, functional pulmonary valve atresia with intact ventricular septum and reversal flow in the large patent ductus arteriosus (PDA). Chest X-ray showed severe cardiomegaly and wall to wall heart. Prostaglandin E1 infusion was started once after birth. After few days, clinical conditions progressively worsened because of right heart failure; a first pharmacological approach to close PDA failed and surgery ligation of PDA was necessary to restore anterograde pulmonary flow and heart size. KW - Wall to wall heart; tricuspid regurgitation; pulmonary atresia; arterial duct DO - 10.32604/CHD.2021.015371