TY - EJOU AU - Elenizi, Khaled AU - Aldeen, Abdullah Sharaf AU - Alotaibi, Nasser AU - Fagir, Nagy AU - Hado, Hussien AU - Aldossari, Mubarak TI - Persistent Left Superior Vena Cava with Severely Dilated Coronary Sinus: A Rare Case Report of Failed CRT-P and Successful Dual-Chamber Pacemaker Implantation T2 - Structural and Congenital Heart Disease PY - 2025 VL - 20 IS - 5 SN - 3071-1738 AB - Persistent left superior vena cava (PLSVC) is a rare congenital anomaly that may complicate cardiac procedures when associated with a dilated coronary sinus (CS) and conduction disturbances. We report the case of a 27-year-old male with Wilson’s disease who presented with complete heart block. Echocardiography showed biatrial enlargement and severe CS dilation, while contrast-enhanced computed tomography (CT) confirmed PLSVC draining into the CS without a bridging vein. Anatomical constraints prevented cardiac resynchronization therapy, and dual-chamber pacemaker implantation proved technically challenging due to lead placement difficulties. This case highlights the importance of thorough preoperative assessment and individualized pacing strategies in patients with PLSVC, in order to anticipate anatomical challenges and optimize outcomes. KW - Persistent left superior vena cava; coronary sinus; complete heart block; Wilson’s disease; cardiac resynchronization therapy DO - 10.32604/chd.2025.071226