TY  - EJOU
AU  - Xu, Yang 
AU  - Zhang, Yaqi 
AU  - Zhu, Meijiao 
AU  - Xue, Pengcheng 
AU  - Ma, Siyu 
AU  - Yu, Di 
AU  - Hu, Liang 
AU  - Zhang, Yuxi 
AU  - Peng, Wei 
AU  - Qi, Jirong 
AU  - Wen, Xuyun 
AU  - Yang, Ming 
AU  - Mo, Xuming 

TI  - A Comprehensive Brain MRI and Neurodevelopmental Dataset in Children with Tetralogy of Fallot
T2  - Structural and Congenital Heart Disease

PY  - 2025
VL  - 20
IS  - 5
SN  - 3071-1738

AB  - <b>Background:</b> The life-course management of children with tetralogy of Fallot (TOF) has focused on demonstrating brain structural alterations, developmental trajectories, and cognition-related changes that unfold over time. <b>Methods:</b> We introduce an magnetic resonance imaging (MRI) dataset comprising TOF children who underwent brain MRI scanning and cross-sectional neurocognitive follow-up. The dataset includes brain three-dimensional T1-weighted imaging (3D-T1WI), three-dimensional T2-weighted imaging (3D-T2WI), and neurodevelopmental evaluations using the Wechsler Preschool and Primary Scale of Intelligence–Fourth Edition (WPPSI-IV). <b>Results:</b> Thirty-one children with TOF (age range: 4–33 months; 18 males) were recruited and completed corrective surgery at the Children’s Hospital of Nanjing Medical University, Nanjing, China. Aiming to promote the neurodevelopmental outcomes in children with TOF, we have meticulously curated a comprehensive dataset designed to dissect the complex interplay among risk factors, neuroimaging findings, and adverse neurodevelopmental outcomes. <b>Conclusion:</b> This article aims to introduce our open-source dataset on neurodevelopment in children with TOF, which covers the data types, data acquisition and processing methods, the procedure for accessing the data, and related publications.
KW  - Tetralogy of Fallot; neurodevelopment; dataset; congenital heart disease

DO  - 10.32604/chd.2025.072242