The polyvinyl chloride PVC is a polymer material widely used for a large variety of applications. The present work focuses on the identification of the physical processes responsible for the mechanical properties of the PVC containing different crystallinities rate applied in large deformation and different strain rates. In order to understand the behavior of the PVC, a thermodynamic modeling is needed. Therefore, the contribution of this approach was demonstrated by experiment and numerical modeling. This comparative study demonstrates that the proposed model provides better agreement with experimental evidence.