Navigating the complex path to precision oncology: The cover image symbolizes the diverse landscape of preclinical patient-derived cultivation models for pancreatic...
This illustration reflects the complex ovarian tumor microenvironment and highlights the role of invariant natural killer T (iNKT) cells in anti-tumor immunity....
It is of great significance to detect prostate cancer more accurately and earlier, especially for those cases where no clear signs are visible on the MRI images....
Tech Science Press (TSP) is pleased to announce that several of its journals have achieved notable improvements in the 2026 XinRui Journal Rankings.· ONCOLOGY RESEARCH: Ranked...
Tech Science Press is pleased to announce that two additional journals have been selected for inclusion in CAB Abstracts, a leading database produced by CAB International (CABI). This milestone...
This paper provides a comprehensive review of recent advances in multi-scale modeling for simulating dynamic damage and fracture in metallic materials,...
3D single object tracking (SOT) based on point clouds is a fundamental task for environmental perception in autonomous driving and dynamic scene understanding...
This paper reviews the research progress and application prospects of machine learning technologies in the field of polymer materials. Currently, machine...
Purpose of this novel review article is to unfold the current scientific worth of high performance polymer nanocomposite nanofibers, owing to growing...
Biobased biodegradable plastics have gained increasing attention as sustainable alternatives to petroleum-based materials in food packaging, offering...
This study provides a new experimental framework to measure the static and dynamic electrical parameters for a solar panel of multiple cells. The study...
The construction industry is a significant contributor to global CO2 emissions, and urgent innovation is needed to mitigate its environmental impact....
Fatigue loads on wind turbines are critical factors that significantly influence operational lifespan and reliability. The passive yaw control of wind...
Oil palm fiber is a natural fiber derived from agricultural biomass and has gained significant attention as an alternative reinforcement material in composite...
Colorectal cancer (CRC) is the second deadliest cancer worldwide, being the presence of metastasis, mainly in the liver, a major contributor to high mortality...
Malignant melanoma (MM) is a highly aggressive skin cancer known for its rapid progression, potential for metastasis, and resistance to treatment. Despite...
Background: An increasing number of studies have shown that ferroptosis is related to the initiation and development of small cell lung cancer (SCLC)....
Cutaneous squamous cell carcinoma (CSCC) is the second most common type of skin cancer and typically involves the head and neck. Systemic therapy is often...
Objectives: To date, predictive and prognostic biomarkers for Bladder Cancer (BC) remain lacking. Existing literature underscores the potential of metabolomics...
Multimodal emotion recognition has emerged as a key research area for enabling human-centered artificial intelligence, supported by the rapid progress...
In materials science and engineering design, high-fidelity and high-efficiency numerical simulation has become a driving force for innovation and practical...
The rapid evolution of chemical biology, medicinal chemistry, and molecular pharmacology continues to drive the discovery of innovative anticancer compounds...
Cancer development and therapeutic response are governed not only by genetic alterations but also by dynamic regulatory mechanisms at the epigenetic and...
The transition toward decentralized smart grids is reshaping the way energy is generated, exchanged, controlled, and consumed. The increasing penetration...
Cancer remains one of the leading causes of morbidity and mortality worldwide, and its onset and progression are closely linked to dysregulated epigenetic...
We propose a special issue titled "Innovative Smart Polymeric Materials for Sustainable Energy Solutions: Bridging Advances in Energy and Biomedical...
Further advancements in the exploitation of unconventional resources, such as tight gas, shale gas, shale oil, coalbed methane, and natural gas hydrate,...
In today’s digital era, patterns are omnipresent, shaping many aspects of our lives. These patterns can be physically observed or computationally identified...
This special issue, “Applied Artificial Intelligence: Advanced Solutions for Engineering Real-World Challenges,” showcases the transformative power of...
This paper provides a comprehensive review of recent advances in multi-scale modeling for simulating dynamic damage and fracture in metallic materials,...
3D single object tracking (SOT) based on point clouds is a fundamental task for environmental perception in autonomous driving and dynamic scene understanding...
This paper reviews the research progress and application prospects of machine learning technologies in the field of polymer materials. Currently, machine...
Purpose of this novel review article is to unfold the current scientific worth of high performance polymer nanocomposite nanofibers, owing to growing...
Biobased biodegradable plastics have gained increasing attention as sustainable alternatives to petroleum-based materials in food packaging, offering...
This study provides a new experimental framework to measure the static and dynamic electrical parameters for a solar panel of multiple cells. The study...
The construction industry is a significant contributor to global CO2 emissions, and urgent innovation is needed to mitigate its environmental impact....
Fatigue loads on wind turbines are critical factors that significantly influence operational lifespan and reliability. The passive yaw control of wind...
Oil palm fiber is a natural fiber derived from agricultural biomass and has gained significant attention as an alternative reinforcement material in composite...
Colorectal cancer (CRC) is the second deadliest cancer worldwide, being the presence of metastasis, mainly in the liver, a major contributor to high mortality...
Malignant melanoma (MM) is a highly aggressive skin cancer known for its rapid progression, potential for metastasis, and resistance to treatment. Despite...
Background: An increasing number of studies have shown that ferroptosis is related to the initiation and development of small cell lung cancer (SCLC)....
Cutaneous squamous cell carcinoma (CSCC) is the second most common type of skin cancer and typically involves the head and neck. Systemic therapy is often...
Objectives: To date, predictive and prognostic biomarkers for Bladder Cancer (BC) remain lacking. Existing literature underscores the potential of metabolomics...
Multimodal emotion recognition has emerged as a key research area for enabling human-centered artificial intelligence, supported by the rapid progress...
In materials science and engineering design, high-fidelity and high-efficiency numerical simulation has become a driving force for innovation and practical...
The rapid evolution of chemical biology, medicinal chemistry, and molecular pharmacology continues to drive the discovery of innovative anticancer compounds...
Cancer development and therapeutic response are governed not only by genetic alterations but also by dynamic regulatory mechanisms at the epigenetic and...
The transition toward decentralized smart grids is reshaping the way energy is generated, exchanged, controlled, and consumed. The increasing penetration...
Cancer remains one of the leading causes of morbidity and mortality worldwide, and its onset and progression are closely linked to dysregulated epigenetic...
We propose a special issue titled "Innovative Smart Polymeric Materials for Sustainable Energy Solutions: Bridging Advances in Energy and Biomedical...
Further advancements in the exploitation of unconventional resources, such as tight gas, shale gas, shale oil, coalbed methane, and natural gas hydrate,...
In today’s digital era, patterns are omnipresent, shaping many aspects of our lives. These patterns can be physically observed or computationally identified...
This special issue, “Applied Artificial Intelligence: Advanced Solutions for Engineering Real-World Challenges,” showcases the transformative power of...
In this research, an effective method has been developed to bond wood panel adhesives of good performance using biosourced lignin and chitosan as the two main raw materials. Lignin was thus modified by a deep eutectic solvent (DES) and maleic anhydride (MA), respectively. Then DES/MA modified lignin was reacted with glyoxal to obtain a new environmentally friendly lignin-glyoxal (LG) resin. Next, chitosan was added as a bio-crosslinker to the synthesised LG resin. Finally, the performance…
This study presents a systematic evaluation of bamboo-derived activated carbons (ACs) prepared using three alkaline activating agents-KOH, KHCO3, and K2CO3-for efficient formaldehyde adsorption. The pore structures of the resulting ACs were modulated by varying the alkali-to-carbon (A/C) ratio from 1:1 to 4:1, and the effects on microstructure and adsorption performance were thoroughly investigated. Among all samples, AC-MB@KOH(3) demonstrated superior performance, featuring a high specific surface area of 2141.77 m2/g and a removal efficiency of 90%, attributed to…
Amidst escalating global energy demands and the depletion of fossil fuel reserves, there is an urgent need to develop energy storage materials derived from low-cost and sustainable biomass. Lignin, an abundant aromatic polymer, has gained increasing recognition as a highly promising precursor for electrode materials due to its low cost, high carbon content, and rich functional groups. For electrochemical energy storage applications, lignin-derived carbon materials, including porous carbon, carbon fibers, and carbon aerogels, demonstrate considerable…
The increasing demand for sustainable construction materials has driven research into non-wood biomass for engineered composites. This study reports the preliminary fabrication and evaluation of cross-laminated panels (CLPs) made from Nipah palm (Nypa fruticans) petioles bonded with a bio-epoxy resin adhesive. Panels were manufactured at three target densities (400, 600, and 800 kg/m3) and evaluated for their physical, mechanical, and microstructural properties. Physical tests included moisture content, water absorption, and thickness swelling, while mechanical tests measured compressive…
Citric acid adhesive is an alternative to formaldehyde-based adhesives that are more environmentally friendly because they are non-toxic and made from natural ingredients. This study aims to determine the effect of variations in citric acid adhesive concentrations on the physical and mechanical properties of jabon plywood. This study used citric acid adhesive with variations in citric acid (CA) concentrations of 59%, 69%, and 79%. Physical property tests include density, moisture content (MC), water absorption (WA),…
This study characterizes biocomposites derived from jicama starch and reinforced with microfibers obtained from jicama bagasse (JB). The incorporation of jicama bagasse microfibers into the jicama matrix was systematically varied at concentrations of 1, 2, 3, 4, and 5 wt%. The starch film and biocomposite were prepared using solution casting methodologies, employing glycerol as a plasticizing agent. The biocomposites were characterized using Fourier-transform infrared spectroscopy, X-ray diffraction analysis, and scanning electron microscopy. In addition, the…
In the early years of the Industrial Revolution, the extensive use of fossil resources and energy-intensive production methods was widely accepted, even celebrated, as signs of progress. However, growing concerns over environmental degradation, resource depletion, and climate change have necessitated a transition toward more sustainable and environmentally responsible production strategies. Within this context, wick-and-oil flame synthesis has emerged as a simple, energy-efficient, and cost-effective method that utilizes natural oils as both fuel and renewable carbon…
Wound healing is a complex and dynamic process essential for restoring the integrity of damaged skin. It requires wound dressings that actively regulate the wound microenvironment by preventing infection, maintaining moisture balance, allowing gas exchange, and managing exudate. Natural polysaccharides, such as konjac glucomannan (KGM), chitosan, and cellulose, are well suited to this role because of their biocompatibility, biodegradability, and intrinsic bioactivity. Extensive research has focused on developing polysaccharide-based wound dressings with enhanced functionality to…
Background: Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, with a poor prognosis in advanced stages. Although histological tumor grading is an established prognostic parameter, it often fails to capture the biological heterogeneity of RCC. Therefore, identifying novel biomarkers could enhance early diagnosis and improve predictive accuracy. Here, we aimed to test whether immunophenotypes of specific glutathione peroxidase (GPX) family members may have prognostic value in RCC. Methods: We…
Background: In head and neck squamous cell carcinoma (HNSCC), solute carrier family 16 member 1 (SLC16A1) is associated with tumor advancement and reduced sensitivity to ferroptosis, yet the molecular basis of these effects remains unclear. This study seeks to uncover how SLC16A1 contributes to HNSCC tumorigenesis. Methods: To elucidate how SLC16A1 drives HNSCC progression via ferroptosis resistance, we performed RNA sequencing on SLC16A1-knockdown HNSCC cells and controls, followed by functional validation. We next systematically assessed…
Background: Breast cancer is the leading cause of cancer-related deaths in women, primarily due to distant metastasis. Metabolic reprogramming plays a critical role in tumor growth and spread, but the metabolic mechanisms underlying metastasis in breast cancer remain unclear. The primary objective of this study is to identify molecular targets mediating breast cancer progression and to evaluate whether targeting the metabolic reprogramming represents a potential therapeutic strategy. Methods: To uncover key metabolic regulators involved in…
Melatonin, an endogenous indoleamine primarily synthesized in the pineal gland, has emerged as a promising adjunctive agent within integrative oncology due to its pleiotropic biological actions. Beyond its well-known chronobiological functions, melatonin exerts potent redox-regulatory, anti-inflammatory, oncostatic, and immune-modulating effects that are relevant across multiple stages of carcinogenesis and cancer therapy. Oxidative stress (OS), defined as an imbalance between reactive oxygen and nitrogen species (ROS/RNS) generation and antioxidant defenses, plays a central role in DNA…
Background: Bisphenol A (BPA) is a widely used industrial chemical and endocrine-disrupting compound, and accumulating evidence suggests that it may contribute to prostate cancer progression; however, the underlying molecular mechanisms remain incompletely elucidated. This study aimed to elucidate the molecular targets and signaling pathways underlying BPA-induced prostate cancer progression. Methods: In this study, an integrated strategy combining network toxicology, molecular docking, and molecular dynamics simulations was employed to identify potential BPA-related targets and signaling pathways…
In vivo Chimeric Antigen Receptor (CAR)-T cell therapy reprograms a patient’s own T cells directly inside the body, bypassing the complex and costly traditional manufacturing process. This is achieved by systemically delivering viral or non-viral vectors that genetically modify endogenous T lymphocytes to produce functional CAR-T cells de novo. By eliminating ex vivo cell processing, this strategy can simplify workflows, reduce costs, improve accessibility, and allow faster treatment. Key delivery platforms include engineered lentiviral and adeno-associated viral (AAV)…
Background: Cancer remains one of the leading global health challenges, with lung cancer (LC), breast cancer (BC), and colorectal cancer (CRC) among the most prevalent and deadly malignancies. The intratumoral microbiota (IM), a distinct microbial ecosystem within tumor tissues, has recently emerged as a potential modulator of carcinogenesis, immune responses, and metastatic progression. However, comparative cross-cancer analyses remain limited. Therefore, this study aimed to compare the IM across these cancer types, with particular emphasis on…
The advent of immune checkpoint inhibitors (ICIs) targeting PD-1, PD-L1, and CTLA-4 has transformed the therapeutic landscape of advanced non-small cell lung cancer (NSCLC), and recent clinical trials have extended their application to resectable disease. Multiple randomized phase III trials have demonstrated that neoadjuvant and adjuvant immunotherapy, particularly when combined with platinum-based chemotherapy, significantly improves pathological complete response (pCR), major pathological response (MPR), event-free survival (EFS), disease-free survival (DFS), and overall survival (OS) compared to
Guest Editors: Qi Chen; Yunhui Tang Deadline: 31 December 2026
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